Clinical trials: Natural Languages Processing
Thyroid Cancer, Large Language Models
Evaluation of an Artificial Intelligence-enabled Clinical Assistant to Support Thyroid Cancer Management
This study aims to evaluate the clinical feasibility of adopting artificial intelligence (AI)-based models to improve clinical management of thyroid cancer.
- Trial name
- NCT07234539
- Testing
- AI-enabled clinical assistant
- Where
- 2 sites in Hong Kong
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Neonatal Death, Perinatal Death
Leveraging Interactive Text Messaging to Monitor and Support Maternal Health in Kenya
Mobile health (mHealth) interventions such as interactive short message service (SMS) text messaging with healthcare workers (HCWs) have been proposed as efficient, accessible additions to traditional health care in…
- Conditions
- Neonatal Death, Perinatal Death, Depression
- Trial name
- AI-NEO (NCT05369806)
- Testing
- Interactive two-way SMS dialogue
- Where
- 2 sites in Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Allergic Reaction
Analysis of Adverse Events in Anesthesia Using Artificial Intelligence
The interest of health databases in anesthesia is no longer to be demonstrated. The aim of this research was to develop a natural language processing approach to establish a classification of adverse events observed during the…
- Trial name
- ADVENTURE (NCT05185479)
- Where
- France
- Volunteers
- 9,559 people
- Sponsor
- University Hospital, Strasbourg, France
Diabetes
Natural Language Processing and Quality Assessment in Primary Care
The investigators propose to use a Natural Language Processing System (NLP) to provide an initial baseline report for primary care patients at risk for diabetes and cardiovascular complications that will include: a) evidence of…
- Trial name
- NCT01023243
- Testing
- Brochure: Care of the Feet for Those at Risk, Quality Survey: foot exam, tobacco and aspirin use
- Where
- United States
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Crohn's Disease (CD)
Research on the Whole Process of AI Intelligent Management System for the Diagnosis and Treatment of Inflammatory Bowel Diseases
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a chronic immune-mediated disorder requiring long-term management.
- Conditions
- Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Crohn's Disease (CD), Ulcerative Colitis (UC), Artificial Intelligence (AI)
- Trial name
- NCT07590271
- Where
- Taiwan
- Volunteers
- 4,500 people
- Sponsor
- Taichung Veterans General Hospital
Psychosis, Schizophrenia Disorders
HYEEG Discourse in Psychosis: A Neurobehavioural Study
This multimodal study explores the mechanisms underlying social dysfunction in individuals with schizophrenia. It focuses on the relationship between disorganized communication and social interaction, aiming to identify…
- Trial name
- DISCOURSE-NB (NCT06978803)
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Advanced Care Planning, Shared Decision Making
Advance Care Planning: Communicating With Outpatients for Vital Informed Decision
This Pre-Post, open-cohort design, pragmatic trial with 150 clinicians and will evaluate the effectiveness of the use of telehealth Advanced Care Planning (ACP) Program by comparing ACP documentation among 13,000 patients over 65
- Conditions
- Advanced Care Planning, Shared Decision Making, Video Decision Aids, Communication Skills
- Trial name
- ACP-COVID (NCT04660422)
- Testing
- VitalTalk communication skills training, ACP Decisions Video Program, Intervention training:
- Where
- United States
- Volunteers
- 42,019 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Eye Diseases
Multimodal Machine Learning for Auxiliary Diagnosis of Eye Diseases
With rapid advancements in natural language processing and image processing, there is a growing potential for intelligent diagnosis utilizing chatGPT trained through high-quality ophthalmic consultation.
- Trial name
- NCT05930444
- Testing
- Multimodal Machine Learning Program for Auxiliary Diagnosis of Eye Diseases
- Where
- 3 sites in China
- Volunteers
- 9,825 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Psychosis, Schizophrenia
CBTpro: Scaling up CBT for Psychosis Using Simulated Patients and Spoken Language Technologies
The primary objective of this grant is to develop and evaluate an Artificial Intelligence-based clinical training tool--CBTpro--to support high-quality skills training in CBT for psychosis (CBTp).
- Conditions
- Psychosis, Schizophrenia, Schizo Affective Disorder, Bipolar Disorder
- Trial name
- CBTpro (NCT05127837)
- Testing
- CBTpro
- Where
- 13 sites in United States
- Volunteers
- 601 people
- Sponsor
- University of Washington
Palliative Care, Generative Artificial Intelligence
Patient Aid for Theory-Driven Health Communication (PATH): Translating Goal-Power Theory Into an Instrument and Generative AI Support for Palliative Care Communication
The goal of this clinical trial is to learn whether an artificial intelligence (AI)-supported communication tool can help improve communication between people receiving palliative care and their healthcare providers.
- Conditions
- Palliative Care, Generative Artificial Intelligence, Natural Language Processing (NLP)
- Trial name
- NCT07692711
- Testing
- NurseChat+
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Copd Exacerbation Acute, Readmission
Identification of Patients Admitted With COPD Exacerbations and Predicting Readmission Risk Using Machine Learning
Patients with Chronic Obstructive Pulmonary Disease (COPD) who are admitted to hospital are at high risk of readmission. While therapies have improved and there are evidence-based guidelines to reduce readmissions, there are…
- Conditions
- Copd Exacerbation Acute, Readmission, Machine Learning, Natural Language Processing
- Trial name
- NCT04192175
- Where
- Canada
- Volunteers
- 65,000 people
- Sponsor
- University Health Network, Toronto
Head and Neck Cancer
Towards A Better Paradigm for Head and Neck Cancer Treatment Applying Artificial Intelligence. HNC-TACTIC.
This will be an international, multicenter, retrospective, observational, and data-driven study using secondary data captured in EHRs.
- Trial name
- HNC-TACTIC (NCT05117775)
- Testing
- No intervention - Just description and predictive models
- Where
- Spain
- Volunteers
- 10,000 people
- Sponsor
- Savana Research
Chronic Pain, Cancer Pain
Refining mUltiple Artificial intelliGence strateGies for Automatic Pain Assessment Investigations: RUGGI Study
This single-center, non-profit, observational-interventional study aims to develop artificial intelligence (AI) models for the automatic assessment of chronic pain (APA - Automatic Pain Assessment).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Pain Assessment
- Trial name
- RUGGI (NCT07038434)
- Testing
- Multimodal AI-Based Pain Assessment
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Valentina Cerrone
Headache Disorders
NLP Headache Speech (NLPH-SPEECH): a Cross-sectional Study on Natural Language Processing Analysing Spoken Monologues by Headache Patients
The research collects spoken descriptions of headache disorders by participants with headache disorders. The speech recordings are analyzed by natural language processing (NLP) tools to analyse linguistic properties of the texts…
- Trial name
- NLPH SPEECH (NCT05204316)
- Testing
- Digital Analysis of Speech
- Where
- Belgium
- Volunteers
- 2 people
- Sponsor
- University Hospital, Ghent
Bibliotherapy
Guided Self-help for Common Mental Disorders
Common mental disorders (CMDs) like depression and anxiety account for a large proportion of disability worldwide. Access to effective treatments like cognitive-behavioral therapy (CBT) is limited and has not reduced the public…
- Trial name
- DWM (NCT04870099)
- Testing
- Doing What Matters in Times of Stress: An Illustrated Guide
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Indiana University
Depression, Anxiety
Potency and Precision Investigation
The overarching goal of this study is to establish initial proof of mechanism for precision interventions in an adult population.
- Trial name
- PAPI (NCT06240091)
- Testing
- DISC-MA
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Woebot Health
Dental Anxiety in Children
AI-Assisted Evaluation of Dental Anxiety in Children: A Machine Learning Approach
This observational study evaluated whether children's dental anxiety could be identified from their speech using artificial intelligence and machine learning methods.
- Trial name
- NCT07797777
- Testing
- Multimodal Speech-Based Dental Anxiety Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Marmara University
Psychosis, Schizophrenia Disorders
DIALOG: Understanding Disorganisation: A Language-focused Global Initiative in Psychosis
Disorganized speech, language and communication, also called 'formal thought disorder,' is a key part of severe mental illnesses like psychosis and mood disorders.
- Conditions
- Psychosis, Schizophrenia Disorders, Bipolar Affective Disorder, Depressive Disorder
- Trial name
- DIALOG (NCT06978465)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Prostate Cancer
NLP-Based Feedback to Improve Risk Comms and Informed Shared Decision Making
In this pilot study, the investigators will show feasibility of the NLP-based feedback system in 20 consultations of men with newly diagnosed prostate cancer.
- Trial name
- NCT05923684
- Testing
- NLP-based Feedback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Neoplasms, Clinical Documentation
Ambient AI Documentation in Oncology Consultations
This study tests whether an artificial intelligence (AI) system can help doctors write medical notes during cancer consultations.
- Conditions
- Neoplasms, Clinical Documentation, Artificial Intelligence in Medicine
- Trial name
- NVC-AI-DOC (NCT07850700)
- Testing
- Ambient AI documentation system
- Where
- Lithuania
- Volunteers
- 250 people
- Sponsor
- National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos