Clinical trials: Natural Orifice Surgery
Cholelithiasis
Transvaginal NOTES Cholecystectomy: Phase I/II Mexico Clinical Trial
Cholecystectomy is one of the most common general surgery procedures performed in the US today and is among top 10 procedures performed in U.S. hospitals annually, and biliary tract disease has been estimated to cost U.S.
- Trial name
- NCT00710502
- Testing
- Transvaginal NOTES cholecystectomy, Laparoscopic cholecystectomy
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad Juarez del Estado de Durango
Colorectal Cancer
Natural Orifice Transluminal Endoscopic Surgery for Colorectal Cancer
The purpose of this study is to assess different hybrid natural orifice transluminal endoscopic surgery techniques in management of colorectal cancer as regard: feasibility of the technique, short term oncologic outcome and…
- Trial name
- NOTES (NCT02549456)
- Testing
- natural orifice specimen extraction, Laparoendoscopic resection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Colorectal Neoplasms, Neoplasms Malignant
Clinical Outcomes of NOSES Versus Traditional Robotic-assisted Surgery for Patients With Colorectal Cancer
In this study, the investigators will compare the clinical outcomes of the natural orifice specimen extraction surgery versus traditional robotic-assisted surgery in the treatment of colorectal cancer.
- Conditions
- Colorectal Neoplasms, Neoplasms Malignant, Complication of Surgical Procedure, Robotic Surgical Procedures
- Trial name
- NOTR (NCT04230772)
- Testing
- Natural Orifice Specimen Extraction Surgery, Traditional Robotic-assisted Surgery
- Where
- 7 sites in China
- Volunteers
- 550 people
- Sponsor
- Taiyuan Li
Prolapse Pelvic, Hysterectomy
Vaginal Natural Orifice Transluminal Endoscopic (vNOTE) Hysterectomy With Uterosacral Suspension
As the adoption of Vaginal natural orifice transluminal endoscopic surgery (vNOTES) expands, attention is shifting from feasibility studies to the refinement of surgical steps that optimize long-term pelvic health.
- Trial name
- VENUS (NCT07413861)
- Testing
- Uterosacral suspension, Hysterectomy by vNOTES approach
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Colorectal Cancer
Short-term and Long-term Outcomes of Colorectal Cancer Treated With Natural Orifice Specimen Extraction Surgery : a National Registry-based Study
Natural orifice specimen extraction surgery (NOSES) has gained widespread recognition among scholars and has gradually been promoted and popularized around the world.
- Trial name
- NCT06350370
- Testing
- Natural orifice specimen extraction
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Colonic Diseases, Rectal Diseases
Assessing Infectious Risk and Visceral Closure in Natural Orifice Translumenal Endoscopic Surgery (NOTES)
The purpose of this study is to determine: 1. What quantity of bacteria is spilled into the abdomen during a colon resection 2. If there is a correlation between the quantity and post-operative infection 3.
- Trial name
- NOTES (NCT01102725)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Colorectal Cancer
Natural Orifice Specimen Extraction Surgery for Colorectal Cancer
The goal of this type of study: a prospective, randomized controlled clinical trial is to assess the safety and feasibility of NOSE surgery to compare the NOSE and conventional laparoscopy groups in Colorectal cancer patients.
- Trial name
- NOSE (NCT05740267)
- Testing
- Natural Orifice Specimen Extraction
- Volunteers
- 318 people
- Sponsor
- Chang Gung Memorial Hospital
Cholelithiasis
Natural Orifice Translumenal Endoscopic Surgery: Laparoscopic-Assisted Transvaginal Cholecystectomy
To determine the feasibility, safety, and efficacy of a novel minimally invasive approach to cholecystectomy and to establish a description of this novel translumenal technique in humans at this institution.
- Trial name
- NCT00910325
- Testing
- Laparoscopic-assisted transvaginal cholecystectomy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Massachusetts General Hospital
Umbilical Hernia, Ventral Hernia
Natural Orifice Translumenal Endoscopic Surgery (NOTES): Laparoscopic Assisted Transvaginal Ventral Hernia Repair
This is a prospective chart review/data collection study of natural orifice translumenal endoscopic surgery (NOTES) for ventral hernia repair, that will include questionnaires administered throughout the study.
- Trial name
- NOTES (NCT01398215)
- Testing
- transvaginal NOTES ventral hernia repair
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Cholelithiasis, Biliary Dyskinesia
Natural Orifice Translumenal Endoscopic Surgery (NOTES) Transvaginal Cholecystectomy
Natural Orifice Translumenal Endoscopic Surgery (NOTES) describes a new field of investigational surgery which uses the endoscope as the primary operative tool.
- Trial name
- NCT00984100
- Testing
- NOTES Transvaginal Cholecystectomy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Colon Cancer
Laparoscopic Right Hemicolectomy With Transrectal Specimen Extraction for Colon Cancer
The purpose of this study is to investigate the preliminary surgical outcomes of laparoscopic right hemicolectomy with transrectal specimen extraction.
- Trial name
- NCT06362902
- Testing
- Laparoscopic right hemicolectomy with transrectal specimen extraction
- Where
- China
- Volunteers
- 37 people
- Sponsor
- National Cancer Center, China
Endometrial Adenocarcinoma, Endometrial Cancer
Comparison of Sentinel Lymph Node Applications in Endometrial Cancer Cases Performed With Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) and Conventional Laparoscopy
Endometrial cancer is a common cancer in women, and surgery is usually the first step in treatment. During surgery, doctors often check nearby lymph nodes to see if the cancer has spread.
- Trial name
- V-COSMOS (NCT07583329)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Cukurova University
Department of Anorectal Surgery, Changhai Hospital Affiliated to Naval Medical University
A Randomized, Controlled, Multicenter, Noninferiority Clinical Study of Perioperative and Oncological Safety in Patients With Rectal Cancer
Laparoscopic natural orifice specimen extraction surgery (NOSES) for low rectal cancer has a good minimally invasive effect. However, the NOSES prognosis studies are all small sample retrospective studies.
- Trial name
- NCT05503381
- Testing
- Laparoscopic radical resection of low rectal cancer with transanal specimens
- Volunteers
- 500 people
- Sponsor
- Changhai Hospital
Appendicitis
Transvaginal Appendectomy
The purpose of this study is to determine the feasibility and safety of transvaginal appendectomy and determine and compare the postoperative pain and quality of life after surgery to standard laparoscopic transabdominal…
- Trial name
- NCT00806429
- Testing
- transvaginal appendectomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Ectopic Pregnancy
Comparison of vNOTES and Laparoscopic Salpingectomy in the Surgical Treatment of Ectopic Pregnancy
This study compares vNOTES salpingectomy and laparoscopic salpingectomy in the treatment of ectopic pregnancy, focusing on outcomes such as operative time, postoperative pain, and recovery.
- Trial name
- vNOTES (NCT07057115)
- Testing
- vNOTES Salpingectomy Group., Laparoscopic Salpingectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Gallstones
Safety Study of Keyhole Gallbladder Surgery With Removal of Gallbladder Via the Stomach Rather Than Through the Skin
The benefits of laparoscopic ("minimally invasive" or "keyhole") surgery for gallbladder removal (cholecystectomy) over open surgical procedures in terms of significant reductions in pain, scarring and recovery time are well…
- Trial name
- NCT01010685
- Testing
- Recovery of gallbladder via gastrotomy instead of via the skin
- Where
- United Kingdom
- Sponsor
- Colchester Hospital University NHS Foundation Trust
Morbid Obesity
Comparison of Stapled and Hand-Sewn Sleeve Gastrectomy
Sleeve gastrectomy is a stapler dependent bariatric procedure. A hand-sewn sleeve gastrectomy can be necessary under certain circumstances.
- Trial name
- NCT03982823
- Testing
- Hand-Sewn Sleeve Gastrectomy, Stapled Sleeve Gastrectomy
- Volunteers
- 13 people
- Sponsor
- Inonu University
Natural Orifice Endoscopic Surgery, Disease, Adnexal
Notes Adnexectomy for Benign Pathology Compared to Laparoscopic Excision
Objective: To compare vNOTES (vaginal Natural Orifice Transluminal Endoscopic Surgery) and established laparoscopic removal of benign adnexal masses Study design: Randomized controlled/single…
- Conditions
- Natural Orifice Endoscopic Surgery, Disease, Adnexal, Laparoscopic Surgery
- Trial name
- NOTABLE (NCT02630329)
- Testing
- vNOTES adnexectomy, Laparoscopic adnexectomy
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Imelda Hospital, Bonheiden
Endometrial Cancer, Extreme Obesity
Transvaginal Natural Orifice Endoscopic Surgery for Extremely Obese Patients With Early-stage Endometrial Cancer
The aim of this study is to investigate the feasibility and efficacy of the v-NOTES approach for extremely obese patients with early-stage type 1 endometrial cancer.
- Trial name
- NCT04240730
- Testing
- Transvaginal natural orifice endoscopic surgery for endometrial cancer staging
- Where
- Turkey (Türkiye)
- Volunteers
- 6 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Antro-pyloric and/or Duodenal Benign or Malignant Obstructions
Endoscopic Gastroenteric Anastomosis With New Tissue Apposing Stent in the Management of Antro-pyloroduodenal Obstruction : Evaluation of Feasibility, Efficacy and Tolerance.
Achieving gastro-jejunal or duodenal anastomosis (GJA ) by exclusive endoscopically is a real goal for many years in the development and research of the transluminal endoscopic surgery (N.O.T.E.S).
- Trial name
- NCT02562157
- Testing
- HYALURONIQUE ACIDE
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique Hopitaux De Marseille