Clinical trials: Natural Pregnancy
Sterility, Female
Patient-centered Outcomes After Permanent Female Sterilization Procedure(POPS Trial)
The purpose of this study is to compare and capture key elements of the patient experience, quality of recovery, preferences and satisfaction after laparoscopic salpingectomy done via 3 different routes.
- Trial name
- POPS (NCT05518175)
- Testing
- Traditional laparoscopy, Single site laparoscopy, V-Notes surgery
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- The University of Texas Health Science Center, Houston
Klinefelter Syndrome, Trisomy X
The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy
This study is designed to research the natural history of neurodevelopment, health and early hormonal function in infants with XXY/Klinefelter syndrome, XYY, XXX and other sex chromosome variations in an effort to identify early…
- Conditions
- Klinefelter Syndrome, Trisomy X, XYY Syndrome, XXXY and XXXXY Syndrome
- Trial name
- NCT03396562
- Testing
- Assessments of Development and Growth
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Natural Pregnancy, Pregnancy, Ovarian
Genomic Imprinting and Assisted Reproductive Technologies
Genomic imprinting, referring to an epigenetic marking resulting in monoallelic gene expression, plays a critical role in development.
- Trial name
- EPIGEN (NCT00773825)
- Where
- France
- Volunteers
- 542 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gynecologic Disease, Inflammation
Inflammatory Markers in Natural Orifice Hysterectomies
The authors aimed to detect inflammatory marker changes in two natural orifice hysterectomies: single-port laparoscopic hysterectomy (SLH) and vaginal hysterectomy (VH).
- Trial name
- NCT04221308
- Testing
- Single port laparoscopic systems
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Derince Training and Research Hospital
Type II Diabetes Mellitus
Evaluation of Innovated Screening Tools for Type 2 Diabetes Among Chinese Population(SENSIBLE STUDY I)
Evaluation of using 2h-UG combined with FPG, AGEsP alone or in combination with FPG in diabetes screening in Chinese natural population
- Trial name
- NCT03025919
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Zhongda Hospital
Pregnancy
Comparison of Two Internet Supported Natural Family Planning Methods
The purpose of this research study is to compare the effectiveness of two natural family planning (NFP) methods that are provided over the internet by the Marquette University Institute for Natural Family Planning.
- Trial name
- NCT00843336
- Testing
- Electronic hormonal fertility monitoring, Self-monitoring
- Where
- 2 sites in United States
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Marquette University
Pregnancy, Autoimmune Thyroid Disease
Changes in Natural Immunity in Pregnant Women With Autoimmune Thyroid Disease
Autoimmune thyroid disease (AITD) is the most common endocrine disorder in women of reproductive age, including during pregnancy. It encompasses two clinical conditions: autoimmune hyperthyroidism and hypothyroidism.
- Trial name
- CIPAT (NCT06925399)
- Where
- Croatia
- Volunteers
- 80 people
- Sponsor
- University of Rijeka
Recurrent Cutaneous Melanoma, Recurrent Lip and Oral Cavity Carcinoma
Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors
This phase I trial studies the side effects and best dose of cord blood-derived expanded allogeneic natural killer cells (donor natural killer [NK] cells) and how well they work when given together with cyclophosphamide and…
- Conditions
- Recurrent Cutaneous Melanoma, Recurrent Lip and Oral Cavity Carcinoma, Recurrent Malignant Endocrine Neoplasm, Recurrent Malignant Female Reproductive System Neoplasm
- Trial name
- NCT03420963
- Testing
- Cord Blood-derived Expanded Allogeneic Natural Killer Cells, Cyclophosphamide, Etoposide
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- M.D. Anderson Cancer Center
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Systemic Lupus Erythematosus
Study of Systemic Lupus Erythematosus
This protocol will evaluate patients with systemic lupus erythematosus (SLE) and their relatives to learn more about how the disease develops and changes over time.
- Trial name
- NCT00001372
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Pregnancy, Fertility
Creighton Model Effectiveness, Intentions and Behaviors Assessment (CEIBA)
The Creighton Model (CrM) FertilityCare System is a natural family planning method that teaches couples to recognize and chart the signs of fertility and infertility in the woman's cycle and to use that knowledge to either…
- Trial name
- CEIBA (NCT01012596)
- Testing
- Creighton Model System of Natural Family Planning
- Where
- 18 sites in United States, Canada
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- University of Utah
Infertility, Female
Use of a Home-based PDG Urine Test to Confirm Ovulation
Infertility affects many people in Ontario and carries a significant amount of emotional, physical and financial burden to those who experience it.
- Trial name
- NCT03230084
- Testing
- Urine PDG test
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bruyère Health Research Institute.
Preterm Birth, Pregnancy
Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes
A major goal of modern perinatal and neonatal medicine is to reduce the rate of developmental disabilities, especially mental retardation.
- Trial name
- NCT00342667
- Where
- 5 sites in United States, Chile and 2 more
- Volunteers
- 4,673 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Malaria
Malaria Prevalence Around Maferinyah, Guinea
Background: Many women in Sub-Saharan Africa get malaria while they are pregnant. Plasmodium falciparum is a parasite that can cause malaria. Placental malaria (PM) caused by P.
- Trial name
- NCT04105855
- Where
- Guinea
- Volunteers
- 3,392 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Carcinoma, Neoplasia; Intraepithelial, Cervix
Evaluation Glizigen® and Ocoxin®-Viusid® in High-grade Cervical Intraepithelial Lesions
Phase II clinical trial, monocentric, not controlled, in patients with high grade cervical intraepithelial lesions. A total of 62 patients with a diagnosis of CIN II, III or carcinoma in situ will be included.
- Conditions
- Carcinoma, Neoplasia; Intraepithelial, Cervix, Glandular Neoplasms, Epithelial Neoplasm
- Trial name
- NCT03549273
- Testing
- Glizigen® + Ocoxin-Viusid®
- Where
- Cuba
- Volunteers
- 62 people
- Sponsor
- Catalysis SL
Pregnancy Rate
Didroxyprogesterone Promotes Natural Pregnancy in Infertile Patients With Endometriosis
Endometriosis (EM) is an important cause of infertility in women of childbearing age. Laparoscopic surgery is the treatment of EM Related infertility is an important method.
- Trial name
- NCT05467852
- Testing
- didroxyprogesterone
- Volunteers
- 300 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Malaria
Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
Malaria caused by Plasmodium falciparum continues to be a global problem with devastating consequences. A greater understanding of the immunologic and parasitologic factors associated with infection and disease is badly needed…
- Trial name
- NCT01168271
- Where
- 2 sites in Mali
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Maternal Neoplasia
IDENTIFY Study: Natural History of Maternal Neoplasia
Background: Pregnant women can get a DNA analysis of their blood. The test tells a woman and her doctor about the DNA of her unborn baby. But some women get test results that are abnormal or not reportable.
- Trial name
- NCT04049604
- Testing
- NIPT
- Where
- United States
- Volunteers
- 365 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Endocrine Disease, Infertility
Evaluation of Women With Endocrine and Reproductive-Related Conditions
This study was designed to allow inpatient and outpatient evaluation of women with a variety of reproductive and endocrine-related disorders for purposes of research and physician education.
- Conditions
- Endocrine Disease, Infertility, Leiomyoma, Endometriosis
- Trial name
- NCT00001850
- Where
- United States
- Volunteers
- 833 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cervical Cancer
p16 and Ki-67 Stainings and Natural Killer (NK) Cells in CIN-II Management
The objective of this study is to evaluate the outcome of cervical intraepithelial neoplasia grade 2 (CIN-II) patients followed up without treatment for 24 months according to p16 and ki-67 immunohistochemical staining and to the…
- Trial name
- NCT02522585
- Testing
- Conservative management
- Volunteers
- 100 people
- Sponsor
- Parc de Salut Mar