Clinical trials: Nausea, Postoperative
Postoperative Nausea and Vomiting
Drug and Dose Adjustment in Preventing Postoperative Nausea and Vomiting
The aim is to evaluate the effectiveness of different regimens of prophylactic Ondansetron, Dexamethasone, or both, on the incidence and severity of post-operative nausea and vomiting.
- Trial name
- NCT04719741
- Testing
- Parallel Assignment
- Where
- Jordan
- Volunteers
- 1,000 people
- Sponsor
- Jordan Hospital
Laparoscopic Cholecystectomy, Pain
ICOUGH Bundle and Postoperative Pain and Nausea After Laparoscopic Cholecystectomy
This study will use a randomized controlled experimental research design. The population of the study will consist of all adult patients who undergo laparoscopic cholecystectomy at the General Surgery Clinic of Atatürk University…
- Conditions
- Laparoscopic Cholecystectomy, Pain, ICOUGH, NAUSEA
- Trial name
- ICOUGHBundle (NCT06755970)
- Testing
- ICOUGH
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ataturk University
PONV
Phase IIIb Study of APD421 in Combination as PONV Prophylaxis
A comparison of the efficacy of APD421 and placebo when combined with a standard anti-emetic in the prevention of PONV in patients at high risk of Post-operative Nausea and Vomiting (PONV).
- Trial name
- NCT02337062
- Testing
- APD421
- Where
- 25 sites in United States, France and 1 more
- Volunteers
- 1,147 people
- Sponsor
- Acacia Pharma Ltd
PONV
Electroacupuncture Plus 5-HT3 Receptor Inhibitor for PONV Prevention in High-Risk Patients Undergoing Thoracoscopic Lung Cancer Surgery
This prospective, randomized controlled study aims to evaluate the efficacy and safety of electroacupuncture combined with 5-HT3 receptor inhibitor for preventing postoperative nausea and vomiting (PONV) in high-risk patients…
- Trial name
- NCT07515027
- Testing
- Prophylactic administration of dolasetron, Electroacupuncture
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Shanghai Chest Hospital
Postoperative Pain, Chronic Pain Post-Proceduraal
QLB and Radical Cystectomy, Postoperative Pain
There are ca 1000 new cases of bladder cancer in Finland/year. The curative therapy for high risk bladder cancer is radical cystectomy. The golden standard is still an open surgery despite development of laparoscopic techniques.
- Conditions
- Postoperative Pain, Chronic Pain Post-Proceduraal, Nausea and Vomiting, Postoperative
- Trial name
- BladderQLB (NCT03328988)
- Testing
- QLB
- Where
- Finland
- Volunteers
- 41 people
- Sponsor
- Tampere University Hospital
Post-operative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy
Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy
Bariatric surgery remains the most effective therapy for obesity. Postoperative nausea and vomiting (PONV) are commonly reported following bariatric surgery.
- Trial name
- NCT03435003
- Testing
- Aprepitant 80 mg Oral Capsule, scopolamine transdermal, Total intravenous anesthesia
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Postoperative Nausea and Vomiting, Hysterectomy
Effect of SmtO2 Guided Care on PONV (iMODIPONV)
This randomized controlled trial is to investigate if SmtO2-guided management on top of the usual care, compared with the usual care only, during laparoscopic hysterectomy significantly reduces the incidence of PONV.
- Conditions
- Postoperative Nausea and Vomiting, Hysterectomy, Tissue Oxygenation, Cardiac Output Management
- Trial name
- iMODIPONV (NCT03641625)
- Testing
- Muscular tissue oxygen saturation guided care
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Yale University
PONV
Sugammadex Reduces Antiemetic Effect of Dexamethasone
Sugammadex is a medication used for reversal of muscle relaxation during procedures under general anesthesia. It works by encapsulating muscle relaxant molecules with a steroid ring in its structure.
- Trial name
- NCT06901596
- Volunteers
- 100 people
- Sponsor
- Augusta University