Clinical trials: Nausea
Healthy Adult Participants
Exploring the Role of taVNS in Nausea Management
This single-center randomized controlled trial aims to investigate the efficacy of transcutaneous auricular vagus nerve stimulation in alleviating nausea in healthy adults.
- Trial name
- NCT07632456
- Testing
- Vagal Nerve Stimulation
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Daniel Keszthelyi
Post Operative Pain, Nausea and Vomiting, Postoperative
ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery
This is a single center, prospective, double-blinded randomized controlled trial comparing the efficacy of bilateral superficial cervical plexus blocks (BSCPB) with local wound infiltration vs placebo with local wound…
- Conditions
- Post Operative Pain, Nausea and Vomiting, Postoperative, Opioid Use
- Trial name
- NCT05805423
- Testing
- bilateral superficial cervical plexus blocks and local wound infiltration
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis
Biomagnetic Characterization of Gastric Dysrhythmias III
There is a tremendous clinical need for a noninvasive technique that can assess gastric electrical activity and would be repeatable without any exposure to radiation.
- Conditions
- Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial Gastrectomy
- Trial name
- NCT03176927
- Testing
- magnetogastrogram
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Nausea
Noninvasive Markers of Functional Nausea in Children
The researchers propose to study how functional nausea in adolescents may be characterized noninvasively by the use of multichannel electrogastrogram (EGG) and magnetogastrogram (MGG) recordings.
- Trial name
- NCT03593811
- Testing
- Questionnaires, 4 channel electrogastrogram (EGG), 36 channel high resolution electrogastrogram (HR-EGG)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Nausea and Vomiting in Pregnancy
Guided Imagery for Nausea and Well-Being in Pregnant Women
This study aims to evaluate the effect of a guided imagery-based psychoeducational intervention on nausea and vomiting severity and psychological well-being in pregnant women.
- Trial name
- GI-PREG (NCT07544095)
- Testing
- Guided Imagery-Based Psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Inonu University
Nausea and Vomiting, Obesity
A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use
The goal of this study is to measure the effects of using Tradipitant to treat nausea and vomiting induced by GLP-1R agonist use in adults with class I or class II obesity, or adults who are overweight with at least one…
- Trial name
- NCT07446439
- Testing
- Tradipitant
- Where
- 10 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Vanda Pharmaceuticals
Emergence Delirium in Pediatric Anesthesia, Pediatric Anesthesia
The Effect of Paedfusor TCI, Eleveld TCI, and Sevoflurane Anesthesia on Postoperative Awakening Agitation in Pediatric Patients
Emergence delirium is a common complication in pediatric patients undergoing general anesthesia. The aim of this study is to investigate the incidence of postoperative awakening delirium and agitation in pediatric patients aged…
- Conditions
- Emergence Delirium in Pediatric Anesthesia, Pediatric Anesthesia, Postoperative Agitations in Pediatric Patients, Postoperative Nausea and Vomiting (PONV)
- Trial name
- NCT07534956
- Testing
- propofol ( Paedfusor Model), propofol (Eleveld Model), Sevofluorane
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Same-day Discharge, Length of Stay
Preoperative Oral Hydration in the Ambulatory Arthroplasty Population
The purpose of this study is to investigate if the consumption of a complex carbohydrate drink preoperatively, decreases the length of stay and causes for failure to launch in patients undergoing ambulatory total joint…
- Trial name
- NCT05520593
- Testing
- Complex Carbohydrate Drink
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Morning Sickness
The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
The primary objective of this study is to compare the efficacy of Bonjesta for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo.
- Trial name
- NCT05289557
- Testing
- Bonjesta
- Where
- 10 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Duchesnay Inc.
Postoperative Nausea and Vomiting
Phase I PK and Safety Study of Ondansetron Inhalation Powder
The goal of this clinical trial is to learn if LPI-1503 (Ondansetron Inhalation Powder) can deliver ondansetron into blood through inhalation. It will also learn about the safety of LPI-1503.
- Trial name
- NCT07498751
- Testing
- LPI-1503, IV Ondansetron, Oral Ondansetron
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Luxena Pharmaceuticals, Inc.
Pediatric Anesthesia, Postoperative Nausea and Vomiting (PONV)
Early Oral Fluid Intake in Children After Day Surgery
This study investigates the safety and tolerability of early oral clear fluid intake in children aged 1-8 years undergoing elective outpatient non-gastrointestinal surgeries.
- Conditions
- Pediatric Anesthesia, Postoperative Nausea and Vomiting (PONV), Ambulatory Surgical Procedures
- Trial name
- NCT06937684
- Testing
- Early Oral Fluid Intake, Traditional Oral Fluid Intake
- Where
- Turkey (Türkiye)
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Nausea and Vomiting Chemotherapy-Induced, Meditation Training
Meditation for Chemotherapy-Induced Nausea and Vomiting in Women With Breast Cancer
This randomized clinical trial aimed to evaluate the effectiveness of Twin Hearts Meditation in reducing chemotherapy-induced nausea and vomiting among women with breast cancer undergoing chemotherapy.
- Trial name
- Breast Cancer (NCT07470619)
- Testing
- Twin Heart Meditation
- Where
- Cyprus
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Postoperative Pain, Nausea and Vomiting, Postoperative
Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks
The goal of this clinical study is to improve upon the standard practice of utilizing nerve blocks to enhance the satisfaction of patients undergoing shoulder, or foot and ankle surgery regarding their quality of pain control…
- Conditions
- Postoperative Pain, Nausea and Vomiting, Postoperative, Dizziness, Constipation
- Trial name
- Dex-Dex PNB (NCT07099222)
- Testing
- Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks, Ropivacaine with low, non weight based Dexamethasone additive
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Intrathecal Morphine, Caesarean Section
Intravenous Nalbuphine for Prevention of Intrathecal Morphine-induced Nausea and Vomiting in Patients Undergoing Cesarean Section: A Double-blind, Randomized Controlled Trial.
We study efficacy of iv nalbuphine in prevention of intrathecal morphine-induced nausea and vomiting in patients undergoing cesarean section.
- Conditions
- Intrathecal Morphine, Caesarean Section, Postoperative Nausea and Vomiting, Neuraxial Opioid
- Trial name
- NCT06837129
- Testing
- A single dose of 4 mg iv nalbuphine
- Where
- 2 sites in Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Postoperative Pain, Postoperative Nausea
Autonomic Neural Field Block for Visceral Pain in Minimally Invasive Left-Sided Colectomy
Effective postoperative pain control is a core component of enhanced recovery after surgery (ERAS) pathways in colorectal surgery; however, postoperative pain following minimally invasive left-sided colectomy remains a persistent…
- Conditions
- Postoperative Pain, Postoperative Nausea, Opioid Use
- Trial name
- ANfiELD (NCT07351994)
- Testing
- Autonomic Neural Field Block
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Antonio Caycedo, MD
Constipation - Functional, Abdominal Pain (AP)
Co-Development and Validation of Colonic Symptom Pictograms for Young People
Severe constipation affects 10% of children, often leading to significant physical and emotional distress. While constipation is commonly associated with impaired bowel movements, it is fundamentally linked to abnormalities in…
- Conditions
- Constipation - Functional, Abdominal Pain (AP), Nausea and Vomitting, Bloating
- Trial name
- NCT07337343
- Testing
- Pictogram comprehension and validation
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Pain, Postoperative, Nausea and Vomiting, Postoperative
Relieving Surgical Pain and Nausea With Light Therapy
The goal of this clinical trial is to investigate the effectiveness of colored (green and blue lens) glasses as a non-pharmacological method in relieving post-surgical pain and postoperative nausea in kidney donors.
- Trial name
- LITENS (NCT06772519)
- Testing
- green colored lens glasses, blue colored lens glasses, colorless (transparent) lens glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nuran Ayşen Pamir Aksoy
Anesthesia, Analgesia
Genetic Variants and Perioperative Morbidity and Mortality
Prospective association study to analyse perioperative patients' outcome. Outcome comprises intraoperative and postoperative complications e.g.
- Conditions
- Anesthesia, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT02124499
- Where
- Switzerland
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Edema, Bruising
Steroids for Rhinoplasty: Pain, Nausea, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of medrol dosepaks (oral corticosteroids) on postoperative outcomes among patients undergoing rhinoplasty by Facial Plastic Surgeons at Vanderbilt.
- Conditions
- Edema, Bruising, Nasal Obstruction, Postoperative Pain
- Trial name
- NCT06483204
- Testing
- Medrol 4 MG Oral Tablet Includes Medrol Dosepak
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Opioid Use, Pain, Postoperative
Outcome of Multimodal Anesthesia Bern
In the context of the ongoing opioid crisis in the USA and Europe, reducing perioperative opioid use is a growing priority. Multimodal anesthesia (MMA) offers a patient-centered alternative to opioid-free anesthesia, combining…
- Conditions
- Opioid Use, Pain, Postoperative, Postoperative Complications, Postoperative Nausea
- Trial name
- NCT06985069
- Testing
- General anesthesia applying multimodal anesthesia, General anesthesia using conventional opioid-based regimen
- Where
- Switzerland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern