Clinical trials: Nausea
Morning Sickness
The Efficacy and Safety of Bonjesta® for Nausea and Vomiting of Pregnancy in Pregnant Adolescents
The primary objective of this study is to compare the efficacy of Bonjesta for the treatment of nausea and vomiting of pregnancy (NVP) in pregnant adolescents aged 12 to 17 years with placebo.
- Trial name
- NCT05289557
- Testing
- Bonjesta
- Where
- 10 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Duchesnay Inc.
Tonsillectomy
Honey Used as Adjunct Therapy to Tylenol for Post-Op Tonsillectomy Patients
Tonsillectomies are the second most common surgery with over half a million procedures in the United States for 2006. Tonsillectomies are considered a painful surgical procedure performed on children resulting in pain and…
- Trial name
- NCT03931395
- Testing
- Honey, Standard of Care
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Postoperative Pain, Postoperative Nausea and Vomiting
Effectiveness of Low-Dose Ketamine and Intravenous Lidocaine Versus Fentanyl for Postoperative Pain
Background: Rational approaches to perioperative patient management have been used to meet intraoperative analgesic needs and avoid opioid-related adverse effects.
- Trial name
- Vs(versus) (NCT07213687)
- Testing
- Low dose intravenous ketamine
- Where
- Ethiopia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dilla University
Hypotension
Up-Down Determination of the ED90 of Metaraminol to Treat Hypotension During Cesarean Section
The purpose of this study is to find the best dose of metaraminol to be used in patients during elective cesarean sections.
- Trial name
- NCT01108874
- Testing
- Metaraminol
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Postoperative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy
Baclofen in Preventing Postoperative Nausea and Vomiting After Bariatric Surgery
This study aims to evaluate the possible efficacy of baclofen on postoperative nausea and vomiting in patient with morbid obesity who will undergo laparoscopic sleeve gastrectomy.
- Conditions
- Postoperative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy, Morbid Obesity
- Trial name
- NCT05516953
- Testing
- Baclofen Tablets
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanta University
Shoulder Injuries, Anesthesia
The Effects of Preloading Before Beach Chair Position
The main objective of this study is whether preloading before positioning would be effective for less hemodynamic instability. The study also analyzes that patients with preloading will decrease postoperative nausea and vomiting…
- Conditions
- Shoulder Injuries, Anesthesia, Hemodynamic Instability
- Trial name
- NCT04671537
- Testing
- Preloading with crystalloid fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Intrathecal Morphine, Caesarean Section
Intravenous Nalbuphine for Prevention of Intrathecal Morphine-induced Nausea and Vomiting in Patients Undergoing Cesarean Section: A Double-blind, Randomized Controlled Trial.
We study efficacy of iv nalbuphine in prevention of intrathecal morphine-induced nausea and vomiting in patients undergoing cesarean section.
- Conditions
- Intrathecal Morphine, Caesarean Section, Postoperative Nausea and Vomiting, Neuraxial Opioid
- Trial name
- NCT06837129
- Testing
- A single dose of 4 mg iv nalbuphine
- Where
- 2 sites in Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Gynecological Disease
Optimal Haloperidol Dose for Postoperative Nausea and Vomiting Prevention in High-risk Patients
Low-dose haloperidol is known to be effective for the treatment of postoperative nausea and vomiting (PONV). However, precise dose-response studies have not been completed, especially in patients at high risk for PONV who require…
- Trial name
- NCT01639599
- Testing
- Dexamethasone iv injection, Dexamethasone, haloperidol
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Postoperative Pain, Postoperative Vomiting and Nausea
Efficacy Side-effect Score (ESS): Development and Evaluation of a New Tool for Patients After Surgery
We hypothesized that better control of postoperative pain treatment and its side effects by monitoring ESS might influence the degree of mobility and morbidity in surgical patients and consequently reduce LOS.
- Conditions
- Postoperative Pain, Postoperative Vomiting and Nausea, Postoperative Complications, Mental Status Changes Postoperative
- Trial name
- ESScore (NCT02143128)
- Testing
- Efficacy Safety Score, Verbal Numeric Rating Scale
- Where
- 2 sites in Kazakhstan, Russia
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- Vestre VikenHF Kongsberg Sykehus
Postoperative Nausea and Vomiting, Respiratory Conditions Due to Other External Agents
A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery
The investigators will track bariatric patients who received sugammadex versus neostigmine in the post anesthesia care unit until discharge and assess their length of stay and possible nausea / vomiting / hypoxia episodes.
- Trial name
- NCT03276026
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Heated Humidified Carbon Dioxide in Gynaecological Laparoscopic Surgery
Standard Carbon Dioxide Gas Versus Heated Humidified Gas in Gynaecological Laparoscopy
To establish if heated humidified carbon dioxide gas improves pain scores as well as nausea and analgesic requirements in post operative patients compared to standard cold carbon dioxide.
- Trial name
- NCT02319902
- Testing
- Standard cold carbon dioxide gas, Heated humidified carbon dioxide gas
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Fevzi Shakir
Nausea and Vomiting, Chemotherapy-Induced
To Investigate the Effect of Intravenous Ondansetron on Cardiac Conduction as Compared to Placebo and Moxifloxacin in Healthy Adult Subjects
Ondansetron, also known as Zofran, is a marketed compound used for the prevention of nausea and vomiting. This study, called a thorough QT study, will characterize the effects of a single intravenous (IV) dose of ondansetron on…
- Trial name
- NCT01449188
- Testing
- ondansetron, moxifloxacin, saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Reflux Disease, Gastro-Esophageal, Vomiting, Postoperative
Antireflux Suture In One Anastomsis Gastric Bypass
To prevent refulx symptoms in a type of bariatric surgery, a suture is taken.there is no enough evidence in support of or against the suture.
- Trial name
- NCT07148492
- Testing
- Antireflux suture, No Antireflux suture
- Where
- Pakistan
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Khyber Teaching Hospital
Compassion, Bleeding
Comparison of Omentopexy and Clips on the Staple Line During Laparoscopic Sleeve Gastrectomy
Background: Bleeding through the staple line has been reported as one of the most common staple-related complications in laparoscopic sleeve gastrectomy (LSG).
- Conditions
- Compassion, Bleeding, Nausea, Postoperative, Readmission
- Trial name
- NCT06219668
- Testing
- Omentopexy group
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Abortion
Side Effects and Adherence Associated With Doxycycline Use Following Medical Abortion
The effectiveness of antibiotic treatment at reducing post-abortion infection is unclear. The experiences of women prescribed routine antibiotics after medical abortion is missing from the existing evidence.
- Trial name
- NCT01799252
- Where
- 7 sites in United States
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
1mg Vs 3 mg of Granisetron
A COMPARATIVE STUDY BETWEEN 1MG AND 3 MG OF GRANISETRON IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN STRABISMUS OPHTHALMIC SURGERIES DURING GENERAL ANESTHESIA
Investigators aim to determine the optimal dose of granisetron in strabismus ophthalmic surgeries under general anesthesia to prevent postoperative nausea and vomiting
- Trial name
- NCT04918862
- Testing
- Granisetron
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oxygen, Postoperative Nausea and Vomiting
The Effect of Oxygen Given to Patients in the Postoperative Period on Nausea and Vomiting
Carbon dioxide which is insufflated to inflate the abdominal area is absorbed from the peritoneal area and it increases endogenous catecholamines, which may consequently increase nausea and vomiting.
- Trial name
- NCT04597723
- Testing
- oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Palonosetron
Comparison of the Efficacy of Acupressure P6 Point, Dexamethasone and Ondansetron Versus Palonosetron Monotherapy for Preventing Postoperative Nausea and Vomiting in Laparoscopic Surgery
Postoperative nausea and vomiting (PONV) is defined as nausea and/or vomiting occurring within 24 hours after surgery, it commonly affects 20-30% patients but as high as 70-80% patients who are deemed high risk for PONV may be…
- Trial name
- NCT04461093
- Testing
- Acupressure wristband and Palanosetron
- Where
- 2 sites in Malaysia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mohd Zulfakar Mazlan, MBBS
Nausea and Vomiting, Chemotherapy-Induced
A Study to Assess the Safety & Interaction Between GW679769, Dexamethasone, & Ondansetron When Taken by Healthy Adults
GW679769 may affect liver enzymes that metabolize dexamethasone and ondansetron. This study is designed to test the safety and the extent of the GW679769 affect on dexamethasone and ondansetron levels in humans.
- Trial name
- NCT00437229
- Testing
- Casopitant (GW679769) Oral Tablets, dexamethasone, ondansetron
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Nausea, Vomiting
The Effect on Thirst, Nausea-Vomiting and Comfort Levels of Menthol Lozenge Applied After Extubation
It is reported that approximately 17.5 million people die worldwide each year due to cardiovascular diseases, including ischemic heart disease, cerebrovascular disease and rheumatic heart disease.
- Conditions
- Nausea, Vomiting, Thirst
- Trial name
- NCT04994262
- Testing
- Menthol Lozenge
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi