Clinical trials: Navigation, Spatial
Mild Cognitive Impairment, Spatial Navigation
Active Navigation Training
Pilot testing and development of an immersive virtual reality system for spatial navigation training in mild cognitive impairment syndrome.
- Trial name
- ANTaging (NCT05768620)
- Testing
- CAVE, TAU
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Istituto Auxologico Italiano
Isolation, Social, Virtual Reality
Brain Changes in Response to Long-Duration Isolation and Confinement
This study investigates the time course and magnitude of eight months of isolation and confinement in a spaceflight analog facility on brain changes and cognitive performance.
- Conditions
- Isolation, Social, Virtual Reality, Spatial Navigation
- Trial name
- BRAIVE (NCT04532866)
- Testing
- Isolation and Confinement
- Where
- Russia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Spatial Navigation
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is…
- Trial name
- NCT05801861
- Testing
- Active 10-Hz TMS to the parietal cortex, Active single pulse TMS to the parietal cortex
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Ability, Spatial
Evaluation and Optimization of Hearing Devices in 3-D Complex Audio Environments
A methodical evaluation of novel sound changing principles in CE-labelled Sonova brand hearing instruments (e.g. Phonak hearing instruments) is intended to be conducted on hearing impaired participants.
- Trial name
- NCT03514758
- Testing
- several virtual 3-D complex audio environments
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Blindness, Visual Impairment
The Impact of the Years of Blindness on Sleep and Dreaming Processes and the Relationships With Spatial Abilities
This study aims to assess the impact of blindness on sleep and dreaming processes and the relationship with spatial perceptual performance, examining the link with clinical and psychological indices, neurobiological features, and…
- Trial name
- NCT06631807
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istituto Italiano di Tecnologia
Lung Nodules, Biopsy
Efficacy and Safety of Robotic-assisted Bronchoscopy Combined With the ICNVA Strategy in Biopsy of Peripheral Pulmonary Nodules
To assess the efficacy and safety of robotic-assisted bronchoscopy system (bronchial navigation and positioning device) combined with ICNVA strategy for peripheral pulmonary nodule biopsy through a prospective, single-center…
- Conditions
- Lung Nodules, Biopsy, Navigation, Spatial
- Trial name
- NCT07136961
- Testing
- Robot-Assisted Bronchoscopy (RAB)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Cerebral Palsy (CP)
Cortical Correlates of Spatial Navigation Skills in an Immersive Virtual Reality Environment
The goal of this study is to investigate the neural mechanisms that undergoes spatial navigation skills in children/adolescents aged between 8 and 17 years.
- Trial name
- NCT06710301
- Testing
- Preliminary assessment, Navigation task with EEG recording
- Where
- 2 sites in Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Alzheimer Disease, Aging
Spatial and Ocular Trajectories for the Early Diagnosis of Alzheimer's Disease.
Spatial navigation is a high-level cognitive function that enables humans to orientate themselves and move around in space by constructing a mental representation of the environment.
- Trial name
- ACTSOMA (NCT06213766)
- Testing
- Cognitive assessment, Questionnaires, Spatial navigation task with eye-tracking.
- Where
- 3 sites in France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Covid19, Spatial Visualization
Mapping COVID-19 Spread in a Tertiary Hospital
One of the major problems in suppressing the spreading of an epidemic resides in understanding and monitoring its propagation patterns, and in evaluating how these are modified by enforced policies.
- Conditions
- Covid19, Spatial Visualization, Neural Network, Respiratory Disease
- Trial name
- MEDyMAP (NCT04581096)
- Testing
- no intervention
- Where
- 2 sites in Spain
- Volunteers
- 2,646 people
- Sponsor
- Hospital General Universitario de Valencia
Epilepsy Lobe Temporal, Healthy
Spatial Memory and Temporal Lobe Epilepsy
Temporal lobe epilepsy (TLE) can cause memory disorders, including long-term forgetfulness due to a failure to consolidate verbal but also spatial information.
- Conditions
- Epilepsy Lobe Temporal, Healthy, Epilepsy
- Trial name
- EPINAVIG (NCT06847152)
- Testing
- spatial memory test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Visual Impairment
Digital Twin Smart Educational Platform for Visually Impaired Navigation Training
This study evaluates a novel digital twin smart educational platform designed to train visually impaired individuals on safe navigation in Saudi urban environments.
- Trial name
- NCT07641127
- Testing
- Adaptive Multi-modal Digital Twin Navigation Training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- King Salman Center for Disability Research
Inner Ear Disease, Equilibrium; Disorder, Labyrinth
Unilateral Peripheral Vestibular Dysfunction: Reeducation and Spatial Orientation.
Motor control includes postural control and voluntary movement. For an optimal motor control it is necessary that brain integrates vestibular, visual and somatosensorial inputs properly, in a nonlinear way.
- Conditions
- Inner Ear Disease, Equilibrium; Disorder, Labyrinth, Spatial Navigation
- Trial name
- NCT03171181
- Testing
- Vestibular reeducation
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Traumatic Brain Injury
Combinated Cues and Virtual Spatial Navigation
Many patients suffer from a topographical disorientation after a traumatic brain injury. Virtual Reality settings allow us to develop navigational cues, in order to rehabilitate patients or to help them in daily life.
- Trial name
- CombiVirtual (NCT03534128)
- Testing
- Evaluation of the effect of cues on virtual spatial navigation using a virtual district
- Where
- 4 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Ressources Francilien du Traumatisme Crânien
Epilepsy, Autobiographical Memory
Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings
The goal of this observational study is to develop novel methods for integrating multimodal data streams with invasive neural recordings to study autobiographical memory (AM) formation in individuals with implanted…
- Trial name
- CAPTURE (NCT06883981)
- Testing
- Free and Cued Recall Memory. Temporal Sequence and Spatial Memory
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Utah
Ability, Spatial
Evaluation and Optimization of Hearing Devices in 3-D Complex Audio Environments Study 3 (HEAR3D_CE3)
A methodical evaluation of novel sound changing principles in CE-labelled Sonova brand hearing instruments (e.g. Phonak hearing instruments) is intended to be conducted on hearing impaired participants.
- Trial name
- NCT04180254
- Testing
- Effect of several processing on the auditory distance perception
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sonova AG
Spine Fusion, Spine Injury
Spine Surgery Video Observation Study. The Creation of a Benchmark Video (RGB-Depth) Dataset to Investigate the Feasibility of Developing a Markerless Tracking System for Spine Surgery.
The primary study objective is to build a video dataset, consisting of both colour and depth information, of spine surgery that includes both 'open' and 'minimally invasive' (MIS) surgeries.
- Conditions
- Spine Fusion, Spine Injury, Spine Degeneration, Navigation, Spatial
- Trial name
- SPIVOS (NCT06580379)
- Testing
- Spine surgery
- Volunteers
- 25 people
- Sponsor
- Imperial College London
Mild Cognitive Impairment, Alzheimer's Disease
Enhancing Spatial Navigation Using Non-Invasive Brain Stimulation
Remembering how to travel from one location to another is critical in everyday life, yet this vital ability declines with normal aging and can be further affected by conditions that disproportionately affect the elderly, such as…
- Trial name
- NCT01958437
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Ability, Spatial
Evaluation and Optimization of Hearing Devices in 3-D Complex Audio Environments Study 2
A methodical evaluation of novel sound changing principles in CE-labelled Sonova brand hearing instruments (e.g. Phonak hearing instruments) is intended to be conducted on hearing impaired participants.
- Trial name
- HEAR3D_CE2 (NCT03774030)
- Testing
- several virtual 3-D complex audio environments
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Sonova AG
Scoliosis Idiopathic, Navigation, Spatial
Preoperative and Peroperative Comparison Between 3D Spine Reconstructions
The objective is to collect data from a per-operative navigation system called SURGIVISIO during scoliosis surgeries. A research program is in progress in order super-impose pre-operative 3D reconstructions of the spine performed…
- Conditions
- Scoliosis Idiopathic, Navigation, Spatial, Fusion of Spine, Safety Issues
- Trial name
- Spine-PDCA-OR (NCT04611490)
- Testing
- Spine Fusion
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Aging, Anxiety
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
Two hallmarks of both healthy aging and age-related disease are 1) memory and navigational deficits, particularly in orienting towards goal locations and planning how to navigate to them, and 2) increased susceptibility to stress…
- Conditions
- Aging, Anxiety, Memory Impairment
- Trial name
- NCT03896529
- Testing
- Anticipatory psychological stress
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology