Clinical trials: Near-Infrared Spectroscopy
Parkinson Disease
Brain Activity During Gait in Parkinson's
Lay Summary: Walking problems, such as slow and short steps, are very common in Parkinson's disease and lead to increased falls risk, as well as reduced mobility and quality of life.
- Trial name
- BARC-PD (NCT04863560)
- Testing
- Auditory Cueing, Visual Cueing, tactile Cueing
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 80 people
- Sponsor
- Northumbria University
Fibromyalgia, Chronic Pain
Functional Neuroimaging in Fibromyalgia Patients Receiving tDCS
The purpose of this study is to evaluate effectiveness and cerebral neuronal ability to adaptation in patients with fibromyalgia who receive pregabalin and transcranial direct current stimulation.
- Trial name
- NCT01904097
- Testing
- Pregabalin, Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Acute Kidney Injury, Hepatectomy
Renal Oxygenation-Guided AKI Reduction Trial
Acute kidney injury (AKI) is a common complication after major liver surgery. This study will evaluate whether intraoperative management guided by renal regional oxygen saturation (RrSO₂), measured using near-infrared…
- Trial name
- ROGAR (NCT07816640)
- Testing
- INVOS 5100C regional oxygen saturation monitoring system, RrSO2-guided perioperative management, Usual perioperative management
- Where
- 20 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Chinese PLA General Hospital
Cerebral Aneurysm
NIRS and BIS Monitoring During Cerebral Aneurysm Coiling
This prospective observational study aims to evaluate the effectiveness of Near-Infrared Spectroscopy (NIRS) and Bispectral Index (BIS) monitoring during endovascular coil embolization of cerebral aneurysms under general…
- Trial name
- NIRSBIS-ANEUR (NCT07438275)
- Testing
- Near-Infrared Spectroscopy (NIRS) and Bispectral Index (BIS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dokuz Eylul University
Neurofeedback, Emotion Regulation
Enhancing Emotion Regulation Through Functional Near-infrared Spectroscopy (fNIRS)-Informed Real-time Neurofeedback
The present study aims to employ real-time functional near-infrared spectroscopy (fNIRS) neurofeedback training in combination with cognitive reappraisal strategies for regulating negative emotions in healthy individuals.
- Conditions
- Neurofeedback, Emotion Regulation, Stress
- Trial name
- NCT06866028
- Testing
- Real-time fNIRS neurofeedback from Turbo-Satori
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Pulmonary Hypertension
Acute Exposure of Simulated Hypoxia on Blood and Tissue Oxygenation (aBGA, NIRS)
Randomized crossover trial in patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary Hypertension (CTEPH) to assess the acute response to simulated altitude (FiO2:15.1, equivalent to 2500m above…
- Trial name
- NCT03637114
- Testing
- Simulated Altitude (FiO2: 15.1%)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Arterial Hypotension, Shock
Cerebral Circulation in Critically Ill Children
The principal purpose of this study is to describe the changes in cerebral circulation (assessed by transcranial ultrasound) and oxygenation (assessed by Near InfraRed spectroscopy, NIRS) during resuscitation for hemodynamic…
- Conditions
- Arterial Hypotension, Shock, Cerebral Lesion
- Trial name
- CIRCU-REAPED (NCT03731104)
- Testing
- Near InfraRed Spectroscopy assessment, Transcranial Doppler Ultrasound assessment, Cardiac output assessment
- Where
- 3 sites in France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Transcranial Photobiomodulation, Intervention
Transcranial Photobiomodulation Intervention for Healthy Older Adults
Transcranial photobiomodulation (tPBM) is a novel, non-invasive neurostimulation technique, which has shown compelling potential for cognitive improvement.
- Conditions
- Transcranial Photobiomodulation, Intervention, Functional Near-infrared Spectroscopy, Working Memory
- Trial name
- NCT04608370
- Testing
- Active tPBM session
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- XuanwuH 2
Acute Compartment Syndrome
The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome
This is a prospective observational study to determine the reliability and accuracy of Near Infrared Spectroscopy (NIRS) to detect oxygen flow in the extremities of injured and non-injured soldiers over time.
- Trial name
- NCT01171638
- Testing
- Near infrared spectroscopy (NIRS)
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- J&M Shuler
General Anesthesia, Elective Laparoscopic Cholecystectomy
The Effect of Positive End-Expiratory Pressure Levels on Perfusion Index and Neurocognitive Functions in Geriatric Patients
With the increasing geriatric population, age-related physiological changes and common comorbidities increase the risk of surgical and anesthesia-related complications in this patient group.
- Trial name
- NCT07505550
- Testing
- PEEP levels
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Ankara City Hospital Bilkent
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 1 of 7)
NOTE: This is the first of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882516
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
Epilepsy
Electro- Hemodynamic Activity in Children: Combined Analysis by Video -EEG Spectroscopy and Near-infrared (NIRS )
Epilepsy in children is a major public health issue. It is the first neurological disease of the child.
- Trial name
- AEHCEE (NCT02826915)
- Testing
- Near Infra Red Spectroscopy (NIRS), Electroencephalogram (EEG)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Kolon Kanseri
Erector Spinae Plane Block in Laparoscopic Colorectal Cancer Surgery
Our study will compare patients who underwent laparoscopic surgery for colorectal cancer with and without Erector Spinae Plane Block in terms of renal blood flow and renal function tests.
- Trial name
- NCT07297433
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kayseri City Hospital
Acute Kidney Injury
Renal Oximetry-Guided Anesthesia With Near-Infrared Spectroscopy for Improved Postoperative Outcomes
The trial is a prospective, randomized, single-blind, pilot study investigating whether near-infrared spectroscopy (NIRS)-guided optimization of intraoperative renal oxygen saturation reduces postoperative acute kidney injury…
- Trial name
- ROGAR (NCT07141693)
- Testing
- NIRS-guided management, Standard anesthesia management
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Peripheral Arterial Disease, Cardiovascular Diseases
Mitochondrial Function in Peripheral Arterial Disease
The aim of this study is to investigate the effect of different treatment strategies on mitochondrial function and to correlate in-vitro results to findings from in-vivo measurements of mitochondrial function.
- Trial name
- MIVA (NCT05644158)
- Testing
- Revascularization, Exercise therapy
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Patellofemoral Pain, PFP
Muscle Oxygenation in Patellofemoral Pain
Patellofemoral joint problems account for a significant portion of knee pain and disability. Among these problems, patellofemoral pain is not directly related to any obvious structural abnormality and is characterized by pain in…
- Trial name
- NCT07139158
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Necrotizing Enterocolitis, Very Low Birth Weight Infants
Splanchnic Oxygenation After the First Enteral Feed in Preterm Infants: Prediction of Feeding Tolerance.
Enteral nutrition of preterm and intrauterine growth-restricted (IUGR) infants is still a challenge for neonatologists. Due to the immaturity of the gastrointestinal tract, preterm infants are at high risk of developing feeding…
- Trial name
- NIRS-SO (NCT02383264)
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Acute Ischemic Stroke Patients
Evaluation of rSO2 Between Frontal Lesion Area and Normal Area of Brain by NIRSITX Using NIRS in Acute Ischemic Stroke Patients.
The clinical trial is for acute ischemic stroke patients measuring cerebral oxygen saturation (rSO2) values using pulse oximeter of near-infrared spectroscopy in the frontal lesion area and normal area of brain.
- Trial name
- fNIRS (NCT06250608)
- Testing
- Pulse oximeter, NIRSITX
- Where
- 2 sites in South Korea
- Volunteers
- 35 people
- Sponsor
- OBELAB, Inc.
Fracture of Hip
Hemodynamic Monitoring and Resuscitation in Hip Fractures
Background: Fracture of the hip is a potentially fatal event in an elderly, frail, highly comorbid patient group suffering from dehydration and hypovolemia, and it carries a risk that equals major trauma in young patients in…
- Trial name
- NCT03401138
- Testing
- Preoperative Stroke Volume(SV)-guided fluid optimization
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Anemia
Prevention of Transfusion Related Acute Gut Injury (TRAGI) in Extremely Low Gestational Age Neonates (ELGANs) Using iNO
The investigators seek to determine whether providing inhaled nitric oxide (iNO; a vasodilator) will improve the delivery of oxygen to the brain, kidney and intestines of preterm neonates during and after the subject receives a…
- Trial name
- iNO-TRAGI (NCT02851472)
- Testing
- Inhaled Nitric Oxide
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- New York Medical College