Clinical trials: Near-Infrared Spectroscopy
Myofascial Pain Syndrome, Regional Tissue Oxygen Saturation
Near-Infrared Spectroscopy in Myofascial Pain Syndrome
Myofascial pain syndrome is a regional pain syndrome accompanied by sensorial, motor and autonomic symptoms . myofascial trigger points are most frequently detected in the upper trapezius, levator scapula, and axial postural…
- Trial name
- NCT05022888
- Testing
- regional tissue saturation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Stroke, Electroencephalogram (EEG)
Analysis of Electroencephalogram (EEG) Changes in Subacute Stroke Patients
This study aims to examine how electroencephalogram (EEG) measures change over time in patients with stroke and to compare EEG measures according to the location of brain injury.
- Trial name
- NCT07882082
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Bundang CHA Hospital
A Stabilized Definitive Prosthesis (Procedure 1), Definitive Prosthesis With a Contact Socket (Procedure 1)
Contribution of Near-InfraRed Spectroscopy (NIRS) to the Evaluation of Healing After Amputation of the Leg
50 patients will be included for each of the 2 procedures: For procedure 1: Patients will be selected during multidisciplinary consultations for amputees who are stabilized with their definitive prosthesis and have returned to…
- Conditions
- A Stabilized Definitive Prosthesis (Procedure 1), Definitive Prosthesis With a Contact Socket (Procedure 1), Patients in the Initial Phase (Temporary Prosthesis, Rehabilitation) Following Unilateral Post- Transtibial Amputation (Procedure 2)
- Trial name
- NIRS (NCT02551484)
- Testing
- Measurements using NIRS, TCPO2 measurements, 2-minute walk test
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Physiological Responses to High-Intensity Exercise
Effects of the Q-Collar During High-Intensity Cycling Exercise
This study examined the effects of wearing the Q-Collar during high-intensity cycling exercise. Eleven recreationally trained male participants completed two 5-kilometer cycling time trials: one while wearing the Q-Collar and one…
- Trial name
- NCT07808710
- Testing
- Q-Collar™
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Cardiac Arrest
Vienna Near-Infrared Spectroscopy in Cardiac Arrest Study (VINIRSCA)
Measurement of Near-Infrared Spectroscopy (NIRS) during and after out-of-hospital cardiac arrest (OHCA) in the city of Vienna and the tertiary university hospital of the Medical University of Vienna, Austria.
- Trial name
- VINIRSCA (NCT04778488)
- Testing
- Near-Infrared-Spectroscopy (NIRS)
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Medical University of Vienna
Healthy
Evaluation of the Impact of Laterality on Cerebral Activation During a Motor Task of the Upper Limb in Healthy Subjects
The aim of this study is to investigate the differences in brain activation in healthy subjects during motor tasks, depending on the laterality of the subject, the laterality of the task and the complexity of the task.
- Trial name
- Lateralinirs (NCT05428917)
- Testing
- Simple task, complex task
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
SCD
Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients With Sickle Cell Disease (SCD)
Sickle cell disease (SCD) is an inherited disorder of the blood. SCD can injure the smallest blood vessels, which can cause pain and damage organs all over the body.
- Trial name
- NCT05604547
- Testing
- Non-Invasive Infrared Spectroscopy
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Heart Disease, Neurodevelopmental Disorders
Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease
Infants with congenital heart disease (CHD) are at increased risk for delayed neurodevelopment. Multiple etiological explanations have been proposed, as there seems to be a multifactorial interplay of both prenatal and…
- Conditions
- Congenital Heart Disease, Neurodevelopmental Disorders, Electroencephalography, Near-Infrared Spectroscopy
- Trial name
- NICO (NCT06190210)
- Testing
- electroencephalography, Near-Infrared Spectroscopy, neuronal cell-free DNA
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Manic Episode
Effect of tDCS Combined With Pharmacological Treatments for Bipolar Mania
The goal of this clinical trial is to conduct a randomized double-blind controlled trial to explore the efficacy and safety of transcranial direct current stimulation (tDCS) in the treatment of manic episode (ME) and analyzes the…
- Trial name
- NCT05622552
- Testing
- active group of tDCS
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Dongbin Lyu
Acute Kidney Injury, Hepatectomy
Renal Oxygenation-Guided AKI Reduction Trial
Acute kidney injury (AKI) is a common complication after major liver surgery. This study will evaluate whether intraoperative management guided by renal regional oxygen saturation (RrSO₂), measured using near-infrared…
- Trial name
- ROGAR (NCT07816640)
- Testing
- INVOS 5100C regional oxygen saturation monitoring system, RrSO2-guided perioperative management, Usual perioperative management
- Where
- 20 sites in China
- Volunteers
- 1,200 people
- Sponsor
- Chinese PLA General Hospital
Reconstructive Surgery, Flap Monitoring
Flap Assessment With Regional Oximetry for Early Detection of Compromise in Free Flap Reconstructive Surgery - FLARE Study
After some operations in which tissue is removed, it is necessary to repair the defect with a piece of tissue from another location in the body.
- Trial name
- FLARE (NCT07887256)
- Testing
- Elective free flap surgery, INVOS monitoring
- Where
- 3 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Leiden University Medical Center
Stress
Subjective Feelings of Job Stress and Frontal Activity During Verbal Fluency Test: A Near-infrared Spectroscopy Study
Background and objectives: Recently the news of intern doctors' death due to overloaded work or committing suicide has made the authorities concerned put emphasis on the mental health care of medical staffs and related policies…
- Trial name
- NCT02286180
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Cardiopulmonary Bypass
Validation of Near Infrared Spectroscopy (NIRS) During Heart-Lung Bypass in Children
Non-invasive assessment of blood flow to organs has long challenged clinicians. Recently, near infrared spectroscopy (NIRS) has been recognized as a methodology that may achieve this goal.
- Trial name
- NIRS (NCT00745394)
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Critical Illness, Respiratory Failure
Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness-2
This study is designed to test the hypothesis that poor cerebral perfusion during critical illness is a risk factor for acute and long-term neurological dysfunction among survivors.
- Conditions
- Critical Illness, Respiratory Failure, Shock, Delirium
- Trial name
- CONFOCAL-2 (NCT03141619)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Dr. Gordon Boyd
Hemoglobin, Cerebral Oxygenation
Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics
This study will enroll children and young adults who are scheduled to undergo planned heart surgery or a heart catheterization procedure while under general anesthesia.
- Conditions
- Hemoglobin, Cerebral Oxygenation, Congenital Heart Disease
- Trial name
- NCT07706140
- Testing
- Noninvasive hemoglobin monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Stroke, Dysphagia
Effects of ITBS Combined with NMES on Dysphagia After Stroke
In recent years, research on intermittent Theta Burst Stimulation (iTBS), as a special high-frequency （repetitive transcranial magnetic stimulation，rTMS） stimulation paradigm, has focused on exploring the effects in healthy…
- Conditions
- Stroke, Dysphagia, Intermittent Theta Burst Stimulation, Neuromuscular Electrical Stimulation
- Trial name
- NCT06464835
- Testing
- Transcranial magnetic stimulation
- Where
- China
- Volunteers
- 45 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Coronary Artery Disease
Effect of Evolocumab on Coronary Plaque Characteristics
The aim of the study is to assess the effect of evolocumab on coronary plaque morphology using intravascular imaging and gene expression analysis of peripheral blood mononuclear cells (PBMC) in patients with stable CAD on…
- Trial name
- YELLOW III (NCT04710368)
- Testing
- Evolocumab Injections
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Annapoorna Kini
Prematurity
Effect of Monitoring Devices on Healthcare Provider Performance During Neonatal Resuscitation
Babies born very early (at less than 32 weeks) usually need help to breath right at birth, also called neonatal resuscitation. Healthcare providers (HCPs) are specially trained to provide this help.
- Trial name
- NCT04521725
- Testing
- Respiratory Function Monitor (RFM), Cerebral Near-Infrared Spectroscopy (NIRS)
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of Alberta
TBI (Traumatic Brain Injury)
A Multi-Center Study of Near-Infrared Spectroscopy (NIRS) for Hematoma Detection
The purposes of this study are: 1. To determine the sensitivity and specificity of the Near-Infrared Spectroscopy (NIRS) measurements for identifying intracranial hematomas due to trauma. 2.
- Trial name
- NCT00576147
- Testing
- Infrascanner
- Where
- 4 sites in United States
- Volunteers
- 431 people
- Sponsor
- InfraScan, Inc.
Critical Care
Near Infrared Spectroscopy for Blood Glucose Measurement in Critical Care Settings
Luminous Medical, the Sponsor is developing a glucose monitor for the critical care setting. The Sponsor's ultimate goal is to provide a near-continuous blood glucose monitor that automatically measures glucose.
- Trial name
- NCT01168089
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- InLight Solutions