Clinical trials: Near-Infrared Spectroscopy
COVID-19 Acute Respiratory Distress Syndrome, COVID-19 Pneumonia
Cerebral Autoregulation and COVID-19
This study aims to assess cerebral autoregulation by near-infrared spectroscopy (NIRS) in patients with severe coronavirus disease 19 (COVID-19).
- Trial name
- CA-COVID (NCT04930874)
- Testing
- NIRS (Near-Infrared Spectroscopy)
- Where
- Greece
- Volunteers
- 7 people
- Sponsor
- University of Athens
Cardiacsurgery
Monitoring of Cerebral Blood Flow Autoregulation Using Near Infrared Spectroscopy
Blood flow to the brain is normally regulated to ensure a constant supply of blood with oxygen and nutrients. During heart surgery using cardiopulmonary bypass, blood pressure is kept at a level that may or may not be below an…
- Trial name
- NCT00769691
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Johns Hopkins University
Traumatic Brain Injury
Near-infrared Spectroscopy (NIRS) for Intracranial Hematoma Detection
Traumatic brain injury is a common neurosurgical emergency managed in all tertiary and secondary hospitals. Detecting the underlying pathology is a major challenge especially for surgical cases.
- Trial name
- NCT05189561
- Testing
- near-infrared scanner
- Where
- India
- Volunteers
- 208 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Extremely Low Birth Weight Infants
Post-Extubation Assessment of Clinical Stability in ELBW Infants
This is an observational, proof-of-concept, feasibility study that aims to evaluate the feasibility of a monitoring system that integrates clinical data, high-resolution waveforms from the bedside monitor, regional oxygenation…
- Trial name
- PEACE (NCT06037083)
- Testing
- Oxygen saturation probe, Near infrared spectroscopy sensors, Electrical impedance tomography
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Attention Deficit/Hyperactivity Disorder
The Effects of Vyvanse(TM) on Brain Hemodynamics and Reading
This is a single-blind, Investigator Initiated study to evaluate the safety and efficacy of Vyvanse™ and provide pilot data in two areas: (1) on the use of Near-Infrared Spectroscopy to detect medication effects in children with…
- Trial name
- VBHR (NCT00733356)
- Testing
- Vyvanse
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Kimberley Lakes
Hemiparesis
Post-stroke Motor Rehabilitation Using Functional Near-infrared Spectroscopy-based Brain-computer-interface
Chronic stroke survivors suffering from weaknesses or movement difficulties in their hand/arm are provided a system to aid in at-home rehabilitation for 6 weeks.
- Trial name
- fNIRS-PROMOTE (NCT05258591)
- Testing
- Axem Home
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Axem Neurotechnology Inc.
Diagnostic and Monitoring Anesthesiology Devices Associated With Adverse Incidents
Evaluation the Perfusion of Uterus and Lower Extremities During Cesarean Section With NIRS and Color Doppler
Hypotension after spinal anesthesia for cesarean section is one of the most common perioperative issue, with an incidence up to 83%.Hypotension is mainly induced by the associated sympathetic blockade, with a drop of peripheral…
- Trial name
- NCT02178774
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Hamstring Muscles, Hamstring Shortness
The Sex-Specific Impact of a Single Foam Rolling Session on Peripheral Muscle Oxygenation
The hamstring muscle, as a biarticular muscle, plays a crucial role in both hip extension and knee flexion and is part of the Superficial Back Line, which supports upright posture and prevents excessive flexion.
- Conditions
- Hamstring Muscles, Hamstring Shortness, Hamstring Tightness
- Trial name
- NCT07078448
- Testing
- Foam Roller
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pelin Pişirici
Cerebral Injury
Functional Near Infrared Spectroscopy in Adult Surgery
Brain injury is a serious problem after cardiac surgery. Brain injury can become evident in the form of stroke and cognitive dysfunction after surgery.
- Trial name
- NCT04574440
- Testing
- multichannel fNIRS monitoring
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cognitive Dysfunction, Postoperative, Cognitive Dysfunction
Assessment of Brain Oxygen Drops During Surgery and Related Risk Factors for Cognitive Problems After Heart Surgery
This study examines whether decreases in brain oxygen levels during cardiac surgery are linked to postoperative cognitive dysfunction and identifies other factors that may increase the risk of cognitive impairment.
- Conditions
- Cognitive Dysfunction, Postoperative, Cognitive Dysfunction, Cardiac Surgery
- Trial name
- NCT07361068
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Vision; Disorder, Loss
The Influence of Prone Position for Spinal Surgery on Visual Acuity
This study investigated the effect of desflurane and propofol anesthesia on visual acuity in patients in prone position for spinal surgery.
- Trial name
- NCT03644641
- Testing
- Desflurane Group, Propofol Group
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Hradec Kralove
Coronary Artery Disease (CAD), Stable Angina Pectoris
Identification of Lesion Characteristics in Coronary Plaques Using Multimodality Intravascular Imaging and Novel Photon-counting CT in Stable Angina
Coronary artery disease, caused by the furring up of the heart arteries by atherosclerosis, is a major cause of death in the UK.
- Conditions
- Coronary Artery Disease (CAD), Stable Angina Pectoris, Ischaemic Heart Disease (IHD)
- Trial name
- ILUMINA (NCT07864025)
- Testing
- observational study
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Queen Mary University of London
Anaesthesia
Measuring the Effect of External Pressure on the Regional Cerebral Oxygen Saturation Monitored by Near-infrared Spectroscopy(NIRS) Technology
During general anaesthesia, to ensure sufficient oxygen supply to the brain, the NIRS technology can be used. It consist of two sensors placed on the forehead, and measures the oxygen saturation of the tissue underneath the…
- Trial name
- NCT01971996
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Hypercapnia
Assessment of Cerebral Vasoreactivity Using Near-infrared Spectroscopy (NIRS) in Infants (VARO)
The purpose of this study is to show that a permissive hypercapnia during mechanical ventilation in children under general anaesthesia will improve cerebral perfusion.
- Trial name
- VARO (NCT02429154)
- Testing
- Normocapnia, Mild Hypercapnia
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Walid HABRE
Neurosciences
The Brain Activation During Different Motor Patterns in Healthy Adults
This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF).
- Trial name
- NCT04868929
- Where
- Taiwan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
End Stage Liver Disease
Study of Peripheral Tissue Oxygenation in End-stage Liver Disease Patients During Liver Transplantation
End - stage liver disease can cause many problems to the patients including fatigue, weakness,jaundice, confusion, abdominal pain and distension. Another important problem is the cardiovascular system (heart and blood vessels).
- Trial name
- NCT01794637
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Spinal Cord Injury
Orthostatic Tolerance During FES (Functional Electrical Stimulation)-Walking in Paraplegia
Objective: The objective of this research is to undertake a safety and viability study of FES-evoked stepping in individuals with paraplegia.
- Trial name
- NCT00108043
- Testing
- FES-evoked functional upright gait
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- University of Sydney
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Acute Spinal Cord Injury, Spinal Cord Injuries
Optical Monitoring With Near-Infrared Spectroscopy for Spinal Cord Injury Trial
The study involves the 'first-in-human' evaluation of a novel optical sensor which uses near-infrared spectroscopy (NIRS) technology to assess oxygenation and hemodynamics of the injured spinal cord.
- Trial name
- NCT04811235
- Testing
- Near Infra-Red Spectroscopy (NIRS) Sensor
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of British Columbia
Lower Limb Ischemia
Lower Limb Tissue Oxygenation Using Near-infrared Spectroscopy During Hallux Valgus Operation
In acute lower limb ischemia the main goal of the treatment is to restore the blood before irreversible damage to the soft tissues of the limb.
- Trial name
- INVOHV (NCT04533035)
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Kuopio University Hospital