Clinical trials: Near-Infrared Spectroscopy
Breast Cancer
Adjunctive Efficacy Study Of The SoftScan® Optical Breast Imaging System
The primary study endpoint -SoftScan adjunctive accuracy- will be used to test the hypothesis that the adjunctive combination of the SoftScan with x-ray mammography provides diagnostic accuracy that is significantly better than…
- Trial name
- NCT00267449
- Testing
- SoftScan Optical Breast Imaging System
- Where
- 6 sites in United States, Canada
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- ART Advanced Research Technologies Inc.
TBI (Traumatic Brain Injury)
A Multi-Center Study of Near-Infrared Spectroscopy (NIRS) for Hematoma Detection
The purposes of this study are: 1. To determine the sensitivity and specificity of the Near-Infrared Spectroscopy (NIRS) measurements for identifying intracranial hematomas due to trauma. 2.
- Trial name
- NCT00576147
- Testing
- Infrascanner
- Where
- 4 sites in United States
- Volunteers
- 431 people
- Sponsor
- InfraScan, Inc.
Clinical Suitability of Artificial Intelligence Programs, Near Infrared Spectroscopy
Cerebral Near-infrared Spectroscopy in Patients Undergoing Open Cardiovascular Surgery Using Artificial Intelligence Programs: A Methodological Study
The aim of the present study is to test the accuracy and reliability of AI tools in this regard by interpreting NIRS, which we routinely use for monitoring cerebral perfusion in cardiovascular surgery, with AI tools and comparing…
- Conditions
- Clinical Suitability of Artificial Intelligence Programs, Near Infrared Spectroscopy, Cardiac Surgery
- Trial name
- NIRS for AI (NCT07654244)
- Testing
- CHATGPT GROUP, GEMINI GROUP, COPILOT GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Antalya Health Sciences University
Coronary Atherosclerosis, Endothelial Dysfunction
Assessment of Coronary Plaque Composition
The investigators' hypothesis is that local activation of the endogenous Lipoprotein-associated phospholipase A2 (Lp-PLA2) plays an integral role in early atherosclerosis, and contributes to the mechanism of coronary endothelial…
- Conditions
- Coronary Atherosclerosis, Endothelial Dysfunction, Coronary Small Vessel Disease
- Trial name
- NCT01581632
- Testing
- LipiScan/LipiScan IVUS
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Mayo Clinic
Autism Spectrum Disorder (ASD)
Brain Stimulation and Sensory Integration in Children With ASD
The goal of this clinical trial is to find out if brain stimulation can help improve sensory integration in children ages 6 to 12 with autism spectrum disorder (ASD).
- Trial name
- NCT07182331
- Testing
- Continuous Theta Burst Stimulation to Bilateral DLPFC
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Neurolab Plus
Athletic Performance, Muscle Oxygenation
Effects of Core and Inspiratory Muscle Training on Muscle Oxygenation and Athletic Performance İn Young Soccer Players
The purpose of this randomized controlled trial is to investigate the effects of core training and inspiratory muscle training (IMT) on muscle oxygenation and athletic performance in youth male soccer players aged 15-18.
- Conditions
- Athletic Performance, Muscle Oxygenation, Respiratory Function
- Trial name
- NCT07657065
- Testing
- Core Training Program, Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istinye University
Neonatal Cerebral Oxygenation, Cesarean Section
Effects of Spinal Versus General Anesthesia on Neonatal Cerebral Oxygenation During Cesarean Section
This prospective observational study evaluates and compares the effects of spinal and general anesthesia techniques used during elective cesarean section on neonatal cerebral regional oxygen saturation (crSO₂) during the early…
- Trial name
- NEO-OXY-CS (NCT07477093)
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Akdeniz University Hospital
Fibromyalgia
Brain Response to Single Dose of Pregabalin in Fibromyalgia
Fibromyalgia syndrome represents a "spectrum disorder" characterized by widespread chronic pain, fatigue, sleep disturbances, mood and cognitive alterations.
- Trial name
- NCT02639533
- Testing
- Pregabalin
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Tissue Oxygenation
Postspinal Headache and Near Infrared Spectroscopy (NIRS)
Evaluation of the relationship between postspinal headache and near infrared spectroscopy in cesarean section patients
- Trial name
- NCT04187846
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Hakan Tapar
Spinal Anesthesia
Changes in the Microvascular Reactivity on Leg During Spinal Anesthesia
Anesthesia alters microcirculation and tissue oxygen saturation (StO2). We sought to examine changes in StO2 using near-infrared spectroscopy and a vascular occlusion test (VOT) during spinal anesthesia.
- Trial name
- NCT04806997
- Testing
- Vascular occlusion test
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Pusan National University Hospital
Infertility
Identification of Viable Human Embryos Using Three Different Methods
Infertility affects an increasing number of couples. For many, the choice of treatment is in vitro fertilization (IVF) . Currently, there are no markers fully predictive of developmental competence of IVF embryos.
- Trial name
- NCT01139268
- Where
- 2 sites in Denmark
- Volunteers
- 161 people
- Sponsor
- University of Aarhus
Feeding Intolerance, Necrotizing Enterocolitis
Evaluation of Feeding Intolerance in Premature Infants Using Near Infrared Spectroscopy
Nowadays feeding intolerance (FI) is a common condition among preterm infants. It has been estimated that 16%-29% of premature infants admitted to neonatal intensive care units (NICUs) develop feeding intolerance at some point…
- Conditions
- Feeding Intolerance, Necrotizing Enterocolitis, Premature Infant
- Trial name
- NIRS/NICU2 (NCT02534090)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Prematurity; Extreme
Use of NIRS in Preterm Population Born at Altitude
Near-infrared spectroscopy (NIRS), is a technology that can provide continuous, non-invasive monitoring of oxygenation in tissue.
- Trial name
- NCT04639583
- Testing
- Near-infrared spectroscopy (NIRS) utilization
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of New Mexico
IBD, Maladaptive Behavior Associated With Physical Illness
Brain Activity and Oxygenation Inflammatory Bowel Disease (IBD) Patients
Symptoms such as fatigue, sleep disturbances, anxiety and depression are common in patients with IBD, but the cause is unknown. Understanding how these behaviors occur in IBD and their role in symptoms may help improve management…
- Trial name
- NCT04733456
- Testing
- Quality of life questionnaires, NIRS, Stool Collection
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Postoperative Acute Kidney Injury
Intraoperative Renal Desaturation and Postoperative Acute Kidney Injury
The aim of this study is to investigate the changes in renal regional oxygen saturation (rSO2) monitored by near-infrared spectroscopy (NIRS) and its relationship with the occurrence of postoperative AKI.
- Trial name
- NCT04967105
- Testing
- Near-infrared spectroscopy
- Where
- China
- Volunteers
- 157 people
- Sponsor
- Chinese PLA General Hospital
Recurrent Pregnancy Loss, Anxiety
Cardiac Autonomic and Anxiety Regulation Via Closed-loop nEurofeedback in Recurrent Pregnancy Loss
The goal of this clinical trial is to learn whether right dorsolateral prefrontal cortex (right DLPFC)-targeted fNIRS-BCI online closed-loop neurofeedback, delivered with slow-wave acoustic cueing, can reduce anxiety symptoms and…
- Trial name
- CARE-RPL (NCT07325370)
- Testing
- Right DLPFC fNIRS-BCI closed-loop neurofeedback (real feedback)
- Where
- 2 sites in China
- Volunteers
- 62 people
- Sponsor
- Shenyang Medical College
Heart; Dysfunction Postoperative, Cardiac Surgery
Clinical Assessment of Nonin 7600 Near Infrared Spectroscopy (NIRS) Tissue Oximetry During Cardiovascular Surgery
An observational study designed to evaluate the performance of a new Near Infrared Spectroscopy (NIRS) tissue oximeter device in the clinical setting, including a cerebral sensor and peripheral sensor.
- Trial name
- NCT01289470
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nonin Medical, Inc
Cognitive Function Assessment, Mental Fatigue
Effects of Short-Term Creatine Supplementation on Cognitive Function in Healthy Young Adults
This study examined whether short-term creatine supplementation affects cognitive function in healthy young adults. Participants were randomly assigned to take either creatine monohydrate or a placebo for 10 days.
- Trial name
- NCT07867041
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease
Evaluating a Wireless NIRS Device in the Neonatal Intensive Care Unit
The wireless NIRS sensor will be placed on the participant's forehead, directly underneath the INVOS wired sensor. The wireless NIRS sensor will remain in place for 4 consecutive hours, over 2 consecutive days.
- Conditions
- Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease, Stroke Hemorrhagic, Aneurysm Cerebral
- Trial name
- NCT07732244
- Testing
- Wireless NIRS
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Carotid Artery Stenosis
Effect of Carotid Artery Stent on Evoked Cerebral Blood Oxygenation and Neurocognitive Functioning
Cerebral hemodynamic compromise from internal carotid artery stenosis may be a cause of vascular cognitive impairment that is amenable to treatment by revascularization.
- Trial name
- NCT04651998
- Testing
- MMSE, MoCA, functional near-infrared spectroscopy
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital