Clinical trials: Nearsightedness
Myopia, Myopic Astigmatism
Multicenter Clinical Trial of a Phakic Implantable Collamer® Lens (ICL)
This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian® Implantable Collamer® Lens (ICL) in study participants who have a diagnosis of myopia or myopia with…
- Trial name
- NCT04283149
- Testing
- EVO/EVO+ Visian ICL
- Where
- 14 sites in United States
- Volunteers
- 327 people
- Sponsor
- Staar Surgical Company
Presbyopia, Myopia
Comparison of Two Multifocal Contact Lenses Worn on a Daily Disposable Basis
The purpose of this trial is to evaluate and compare the clinical performance of two multifocal contact lenses.
- Trial name
- NCT01254760
- Testing
- Nelfilcon A multifocal contact lens, investigational, Nelfilcon A multifocal contact lens, commercial
- Volunteers
- 79 people
- Sponsor
- CIBA VISION
Refractive Errors, Myopia
Clinical Comparison of 2 Daily Disposable Contact Lenses - Pilot Study 2
The primary objective of this study is to evaluate the overall performance of PRECISION1 contact lenses when compared to Clariti 1-Day contact lenses.
- Trial name
- NCT04528017
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Alcon Research
Myopia
Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology Lens
The objective of this orthokeratology study is to evaluate the safety and effectiveness of the Arise Orthokeratology Lens with non-spherical posterior peripheral curves
- Trial name
- NCT05984290
- Testing
- orthokeratology lens
- Where
- 6 sites in United States
- Volunteers
- 90 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Ametropia
Clinical Comparison of Two Daily Disposable Contact Lenses - Pilot Study 3
The purpose of this study is to evaluate the overall performance of PRECISION1™ contact lenses when compared to INFUSE™ contact lenses.
- Trial name
- NCT04942925
- Testing
- Verofilcon A contact lenses, Kalifilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Alcon Research
Myopia
The Clinical Comparison of Senofilcon A and Stenfilcon A Contact Lenses
The objective of this study is to compare the clinical performance of senofilcon A lens with the stenfilcon A lens each for one week of daily disposable wear.
- Trial name
- NCT02643004
- Testing
- Senofilcon A, Stenfilcon A
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Evaluation of a Silicone Hydrogel Lens
The purpose of this study is to assess the performance of an investigational contact lens among contact lens wearers.
- Trial name
- NCT01016132
- Testing
- lotrafilcon A contact lens
- Volunteers
- 152 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses
Bilateral dispensing clinical trial of fanfilcon A toric lens verses enfilcon A toric lens over two weeks.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT02423109
- Testing
- fanfilcon A, enfilcon A
- Where
- 2 sites in United States, Canada
- Volunteers
- 44 people
- Sponsor
- CooperVision, Inc.
Myopia and Hyperopia and Presbyopia
Evaluation of Product Performance of a New Silicone Hydrogel Multifocal Contact Lens
The objective of this study is to evaluate the product performance of a new silicone hydrogel daily disposable multifocal contact lens, the Bausch + Lomb (kalifilcon A) Daily Disposable Multifocal Contact Lens, when worn by…
- Trial name
- NCT05660577
- Testing
- new silicone hydrogel daily disposable multifocal contact lens, the Bausch + Lomb (kalifilcon A) Daily Disposable Multifocal Contact Lens
- Where
- 20 sites in United States
- Volunteers
- 301 people
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye Syndrome, Myopia
Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers
The purpose of this study was to evaluate the reduction of contact lens-related dryness symptoms when symptomatic weekly/monthly contact lens wearers were switched to DAILIES® AquaComfort Plus® lenses for a two-week period using…
- Trial name
- NCT01614600
- Testing
- Nelfilcon A contact lenses
- Volunteers
- 88 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Comparison of Topography Guided LASIK With WaveLight® EX500 to SMILE With Zeiss VisuMax
The purpose of this study is to compare Topography Guided Laser In Situ Keratomileusis (LASIK) corneal surgery to Small Incision Lenticule Extraction (SMILE) corneal surgery for the treatment of myopia with astigmatism.
- Trial name
- NCT02987660
- Testing
- Topography Guided LASIK, Small Incision Lenticular Extraction, WaveLight EX500 Excimer Laser System
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Alcon, a Novartis Company
Presbyopia
A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia.
Study of safety and efficacy of UNR844 in subjects with presbyopia.
- Trial name
- READER (NCT04806503)
- Testing
- UNR844
- Where
- 20 sites in United States, Australia and 2 more
- Volunteers
- 234 people
- Sponsor
- Novartis Pharmaceuticals
Myopia
Two Week Cross-Over Study Comparing Two Daily Disposable Contact Lenses
This study seeks to evaluate and compare the clinical performance of two daily disposable soft contact lenses, Proclear 1 Day and 1-Day Acuvue Moist.
- Trial name
- NCT01155323
- Testing
- etafilcon A, omafilcon A
- Where
- Singapore
- Volunteers
- 118 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Pilot Evaluation of a New Galyfilcon A Lens Prototype and Enfilcon A Lens
The purpose of this study is to compare the visual acuity, limbal and bulbar redness of the new galyfilcon A prototype lenses against Avaira® lenses when worn as daily wear for seven (7) days.
- Trial name
- NCT01192542
- Testing
- galyfilcon A prototype lens, enfilcon A lens
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Comparison of New Contact Lens With Current Marketed Lens
The purpose of this study is to validate the clinical performance of a new contact lens design.
- Trial name
- NCT03360110
- Testing
- Phoebe test lens, stenfilcon A lens (control)
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- CooperVision, Inc.
Myopia
Comparative Clinical Evaluation of Daily Disposable Lenses in Symptomatic Daily Disposable Lens Wearers
The purpose of this study is to evaluate the extent to which symptoms improve in symptomatic contact lens wearers when fit with one of two different daily disposable contact lenses.
- Trial name
- NCT01035905
- Testing
- Nelfilcon A contact lens, Narafilcon A contact lens
- Volunteers
- 63 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
Performance Evaluation of Reusable Contact Lenses When Worn For One Month By Habitual Soft Contact Lens Wearers
The purpose of this study was to compare the clinical performance of two different reusable lenses in habitual spherical soft lens wearers.
- Trial name
- NCT06098339
- Testing
- Lens A (fanfilcon A), Lens B (lotrafilcon B)
- Where
- 3 sites in United States, Canada
- Volunteers
- 53 people
- Sponsor
- CooperVision, Inc.
Refractive Errors, Myopia
Performance Assessment of a Modified Daily Disposable Contact Lens
The purpose of this study is to compare visual acuity between two daily disposable contact lenses.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT03762668
- Testing
- Modified delefilcon A contact lenses, Delefilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Myopia
DW Evaluation of Lotrafilcon B Lenses in a Modified Design
The purpose of this study is to demonstrate that Lotrafilcon B AIR OPTIX® AQUA sphere modified design lenses are noninferior to Lotrafilcon B AIR OPTIX® AQUA in overall lens fit by comparing the percent of subjects satisfying the…
- Trial name
- NCT02157909
- Testing
- Lotrafilcon B sphere modified design contact lenses, Lotrafilcon B sphere contact lenses
- Volunteers
- 134 people
- Sponsor
- Alcon Research
Myopia
Dispensing Evaluation of a Galyfilcon A Prototype Lens and a Marketed Contact Lens
The purpose of this study is to compare visual acuity and redness of eyes between a prototype contact lens and an already marketed contact lens.
- Trial name
- NCT01180985
- Testing
- galyfilcon A prototype lens, comfilcon A
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.