Clinical trials: Neck
Cervical Cancer, Vulvar Cancer
Immunogenicity and Tolerability of Broad Spectrum Human Papillomavirus (HPV) Vaccine in Adult and Young Adult Women (V503-004)
This study will assess the safety and immunogenicity of GARDASIL®9 (V503) in 16- to 45-year-old women. The primary hypothesis of the study states that anti-HPV 16, 18, 31, 33, 45, 52, and 58 geometric mean titers (GMTs) at 4…
- Conditions
- Cervical Cancer, Vulvar Cancer, Vaginal Cancer, Genital Warts
- Trial name
- NCT03158220
- Testing
- V503
- Where
- 24 sites in Austria, Belgium and 4 more
- Volunteers
- 1,212 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
The Aim of Our Study is to Prospectively Evaluate the Optic Neuropathy in Nasopharynx Cancer Patients
OPHTHALMOLOGIC EVALUATION OF RADIATION-RELATED OPTIC NEUROPATHY FOLLOWING IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY (IMRT) FOR NASOPHARYNGEAL CARCİNOMA
Primary treatment in nasopharynx cancers is radiotherapy (RT) or chemoradiotherapy (CRT) depending on the stage of the tumor. According to the guidelines, the dose of radiotherapy for primary tumors varies between 66-70 Gy.
- Trial name
- ORONIN (NCT04724590)
- Testing
- IMRT(IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY )
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Neck Pain
Muscle Energy Technique and Static Stretching on Pain Intensity and Functional Disability in Patients With Mechanical Neck Pain
Neck pain is becoming increasingly common throughout the world with a considerable impact on individuals, communities, health-care systems and businesses (Hoy et al, 2011).Neck pain is a common problem within our society…
- Trial name
- MET&SSinNckp (NCT04350918)
- Testing
- Muscle Enery Techniques, Static Stretching
- Where
- Nigeria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University
Head and Neck Cancer
Efficacy and Safety of Ultrasound Hyperthermia Combined With Chemotherapy on Oral and Maxillofacial-Head and Neck Cancer
The purpose of this study is to determine whether Ultrasound Hyperthermia is effective and safe in the treatment of Oral and Maxillofacial-Head and Neck Cancer.
- Trial name
- NCT02353260
- Testing
- Ultrasound Hyperthermia, Docetaxel,Cisplatin,Fluorouracil
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Wei Guo
Esophageal Cancer
Intrathoracic Esophagogastric Anastomosis After Robot Assisted Minimally Invasive Esophagectomy Using STRATAFIX
Determine the safety and efficacy of novel suture in esophageal anastomosis. Specific Aims: 1) Determine the safety of using STRATAFIX suture in esophagogastric anastomosis by measuring anastomotic leak rate; and 2) Determine…
- Trial name
- NCT02609425
- Testing
- Stratafix PGA Suture
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Head and Neck Cancers
SOMESThesia and ALIMentation
Cancer patients are at high risk for undernutrition. A study with head and neck cancer patients showed that 50% suffered from undernutrition (Prevost et al., 2014).
- Trial name
- SOMEST'ALIM (NCT05272917)
- Testing
- Sensorial tests, food preferences questionnaires
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cervical Disease
Initial Study With the CNDS Advanced Cervical Scan to Recalibrate Spectral Data for Use in Future Screening Studies
The purpose of this study is to evaluate whether fluorescence and reflectance spectroscopy can improve the ability to detect the presence of premalignant lesions on the cervix.
- Trial name
- Spectral (NCT02217215)
- Testing
- CNDS Advanced Cervical Scan
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Guided Therapeutics
Cervical Lesion
Bioactive Glass Air-abrasion and Non-carious Cervical Lesions
Evaluating the clinical behavior of composite restorations in NCCLs when the surface is pre-conditioned using bioactive glass air-abrasion has not been reported in the dental literature.
- Trial name
- NCT04578717
- Testing
- Air-abrasion, Adhesive application - Etch&rinse, Adhesive application - Self-etch
- Where
- Syria
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Damascus University
Syndrome Pain
A Trial of TD0019 in Treatment of Cervical Scapulohumeral Syndrome
Cervical scapulohumeral syndrome, which is also called scapulohumeral syndrome or cervical radiculopathy is a group of syndromes related to cervical spine disorders with disfunctional nerves and without inflamation.
- Trial name
- NCT03845959
- Testing
- TD0019 oral capsule
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sao Thai Duong Joint Stock Company
Esophageal Squamous Cell Carcinoma
NCI UNC Project ESCC
Background: Esophageal cancer is a common cause of cancer deaths. Most cases of this cancer are esophageal squamous cell carcinoma (ESCC). Many of these cases come from two parts of the world with high-risk.
- Trial name
- NCT03206125
- Where
- 2 sites in Malawi
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Anxiety, Cervical Cancer Screening
Cervical Cancer Awareness Education to Aid Confidence and Screening upTake (ACT): A Pilot Randomised Control Trial
Cervical cancer remains a major threat to women's health and wellbeing, with the burden disproportionately concentrated in low- and middle-income countries such as Nigeria, where inadequate awareness, limited access to screening…
- Conditions
- Anxiety, Cervical Cancer Screening, Health Education, Wellbeing
- Trial name
- ACT (NCT07863596)
- Testing
- cervical cancer Awareness education to aid Confidence and screening upTake (ACT), Control group
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Teesside University
Papillomavirus Infections
Diversity Analysis of Vaginal Microbiota on Women With High-risk Human Papillomavirus Infection
Since other genital infections enhance HIV susceptibility by inducing inflammation, the investigators study the relationship between the vaginal microbiota composition and the risk of HPV infection, cervical cytological…
- Trial name
- NCT03548740
- Testing
- Human Papillomavirus
- Where
- China
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Head and Neck Cancer
Evaluation of the Implementation of Personalised Follow-up in Head and Neck Cancer
The NHS Long Term Plan for Cancer has set out the strategy to deliver personalised care to every patient treated for cancer (1) to improve experience and quality of life for patients.
- Trial name
- EMPOWER (NCT06170203)
- Testing
- Personalised Follow-up Pathway
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Laryngeal Neoplasms
Irreversible Electroporation(IRE) For Unresectable Laryngeal Neoplasms
The purpose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for unresectable Laryngeal Neoplasms.
- Trial name
- IRE (NCT02430675)
- Testing
- Irreversible electroporation (IRE), NanoKnife
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Forward Head Posture
Effects of Cervical Spine Retraction Exercise With and Without Diaphragmatic Breathing in Forward Head Posture.
This study aims to determine the effect of combining diaphragmatic exercises with cervical retraction exercise on pain, disability, active range of motions of cervical spine and craniovertebral angle in individuals with forward…
- Trial name
- NCT06130969
- Testing
- Cervical Retraction Exercise, Diaphragmatic Breathing, Baseline Treatment
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pain
12 Versus 20 mL PCB for D&E Cervical Prep
More research is needed to investigate methods of pain control for cervical preparation for abortion procedures. Women report pain with paracervical block injection as well as with osmotic dilator placement.
- Trial name
- NCT03356145
- Testing
- 12 mL paracervical block, 20 mL paracervical block
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University
Infections, Papillomavirus
Evaluation of Immunogenicity and Safety of Two 2-dose Human Papillomavirus (HPV) Vaccine Schedules in 9-14 Year Old Girls
This study has been designed to evaluate the immunogenicity and safety of GSK Biologicals' HPV-16/18 vaccine when administered according to alternative 2-dose schedules (0,6 months and 0,12 months) in healthy 9-14 year old…
- Trial name
- NCT01381575
- Testing
- GSK Biologicals' HPV vaccine 580299
- Where
- 33 sites in Canada, Germany and 3 more
- Volunteers
- 1,447 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cervical Cancer, Human Papillomavirus
Accuracy of Portable Colposcopy and HPV Genotypes Among HIV+ Women
This study will evaluate the effectiveness of portable colposcopy when compared to conventional colposcopy (25x magnification of the cervix, the gold standard) and Visualization Inspection with Acetic acid (VIA, with 1x…
- Conditions
- Cervical Cancer, Human Papillomavirus, Human Immunodeficiency Virus
- Trial name
- NCT02338141
- Testing
- Portable colposcopy (Cerviscope), Conventional colposcopy (Wallach Zoomscope)
- Where
- Haiti
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy
Cervical Device Contraception-2 (Nanopaz)
Measure blood progesterone by using cervical device contraception.
- Trial name
- NANOPAZ (NCT00689494)
- Testing
- Nanopaz contraception device
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Lymphedema, Secondary
Skin Biophysical Measures for Assessing Head and Neck Cancer-Related External Lymphedema
Selected measurements in healthy persons of skin tissue dielectric constant as reference values for subsequent use to evaluate patients with head and neck lymphedema.
- Trial name
- NCT04457375
- Testing
- TDC
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
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