Clinical trials: Neck
Cancer Cervix
Carrying Out of Focus Group to Improve Cervical Screening Proposal by Vaginal Self-sampling (APACHE-4/FG).
Despite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths.
- Trial name
- APACHE-4/FG (NCT03420157)
- Testing
- Focus Group
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Cervical Neoplasia
Thermal Imaging for Evaluation of the Cervix
When screening results for cervical premalignant lesions are positive, colposcopy is recommended. This is highly sensitive screening method. However, specificity of the test is of low.
- Trial name
- NCT02908607
- Testing
- Thermal imaging
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Mental Fatigue, Socail Media Usage
Does Mental Fatigue Caused by Social Media Use Affect Biomechanical Properties of Muscles in Young Male Athletes?
The aim of this study is to examine the effect of mental fatigue (MF) induced by 30 minutes of social media use on neck kinematics and neck muscle biomechanical properties in young male athletes.
- Conditions
- Mental Fatigue, Socail Media Usage, Cervical Range of Motion
- Trial name
- NCT07263334
- Testing
- Metal Fatigue Protocols
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Infections, Papillomavirus
Safety and Immunogenicity of GlaxoSmithKline Biologicals' HPV Vaccine 580299 (Cervarix) in HIV Infected Females
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. The current study is designed to evaluate the safety and immunogenicity of GlaxoSmithKline Biologicals' HPV vaccine…
- Trial name
- NCT00586339
- Testing
- Cervarix
- Where
- South Africa
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Oral Squamous Cell Carcinoma
A Prospective, Single-arm Phase II Clinical Trial of Tislelizumab Combined With Platinum Doublet Neoadjuvant Therapy to Improve Mandibular Preservation in Resectable Locally Advanced Oral Squamous Cell Carcinoma.
Given the feasibility of induction chemotherapy in oral cancer and the encouraging remission rates achieved, we explore the clinical application prospects of using tislelizumab in combination with traditional standard…
- Trial name
- B2023-153 (NCT06130007)
- Testing
- Three-Week Treatment Regimen with Trastuzumab in Combination with Docetaxel and Platinum Triple Therapy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Xuekui Liu
Educational Problems, Cervix, Dysplasia
Colposcopy Education Using Operant Learning
Images will be collected during routine colposcopy and paired with their pathology results to be used for resident education
- Trial name
- Colpo (NCT04340011)
- Testing
- Colposcopy
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Xerostomia Due to Radiotherapy (Disorder)
Screening of Biomarkers and Related Mechanisms for RIX
A large number of patients undergoing radiotherapy and chemotherapy are suffering from dry mouth. Due to reduced saliva secretion, patients may experience symptoms such as difficulty chewing and swallowing.
- Trial name
- RIX (NCT06700863)
- Testing
- Radiation Therapy
- Where
- 4 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Infections, Papillomavirus
Immunogenicity and Safety of GSK Biologicals' HPV Vaccine 580299 in Healthy Japanese Females 10-15 Years of Age
Human papillomavirus (HPV) infection has been established as a necessary cause of cervical cancer. GSK Biologicals has developed an HPV vaccine (580299) which targets the 2 most common oncogenic HPV types (HPV-16 and HPV-18)…
- Trial name
- NCT00492544
- Testing
- Cervarix™ (HPV-16/18 L1 VLP AS04)
- Where
- 5 sites in Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries
Evaluation of a New Bioactive Material Versus a Fluoride-Releasing Hybrid Restorative Material in Cervical Lesions
This study will be conducted to evaluate and compare the clinical performance of fluoride, calcium, and phosphate-releasing new bioactive material versus a fluoride-releasing hybrid restorative material in cervical lesions for…
- Trial name
- NCT05149209
- Testing
- cervical restoration
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diagnostic Imaging
PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Safety and Tolerability in Healthy Volunteers and Safety, Tolerability and Diagnostic Performance of BAY86-9596 in Patients With Non-small Cell Lung Cancer, Breast Cancer, Head and Neck Cancer and Patients With Inflammations
Visual assessment of diagnostic PET/CT (positron emission tomography/computed tomography) images obtained after a single intravenous injection of BAY86-9596 in patients with cancer and inflammation
- Trial name
- NCT01089998
- Testing
- BAY86-9596, Fludeoxyglucose (18F)-IBA
- Where
- 2 sites in Netherlands, Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lantheus Biosciences Ltd.
Breast Cancer Screening, Cervical Cancer Screening
Community Gateway to Health Study
The goal of this study is to evaluate the impact of a multi-level intervention on cancer prevention and social determinants of health outcomes.
- Conditions
- Breast Cancer Screening, Cervical Cancer Screening, Colon Cancer Screening, Tobacco Cessation
- Trial name
- NCT07592793
- Testing
- Tools and Training for Cancer Control, Enhancing Social Capital and Civic Engagement
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Uterine Cervical Neoplasms
Conducting Outreach to Improve Cervical Cancer Screening Rates Among Underscreened Patients
The purpose of this project is to determine whether outreach to HIV-negative patients who are overdue for a Pap smear at a New England urban community health center can increase cervical cancer screening rates.
- Trial name
- NCT02427399
- Testing
- Letter and informational sheet, Email, Phone
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Clinical Trial
BONDING TO ENAMEL USING A UNIVERSAL ADHESIVE
Objective: This double-blind randomized clinical trial evaluates strategies for improving the bonding of universal adhesive to enamel in non-carious cervical lesions (NCCL) of a new universal multi-mode adhesive (Ambar Universal…
- Trial name
- RCT (NCT03254693)
- Testing
- 1-step self-etch approach (SE), selective enamel etching (SEE), 1-step self-etch for double time (SE2X)
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Ponta Grossa
Head and Neck Cancer, Oropharyngeal Cancer
Role of Immune Activation in Response of Head and Neck Squamous Cell Carcinoma to Therapy
The purpose of this study is to investigate the role of the immune system in the response of squamous cell cancers of the head and neck to treatment that includes radiation therapy.
- Conditions
- Head and Neck Cancer, Oropharyngeal Cancer, Human Papillomavirus, Squamous Cell Cancer
- Trial name
- NCT01358097
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Noncarious Cervical Lesions
Preheated Composites Vs. Conventional Composites in Noncarious Cervical Lesions
Preheating resin composites is the warming of resin composites by using a heating device (composite warmer) before its placement. Preheating increases the flow properties and allows better adaptation to cavity preparation.
- Trial name
- NCT05533255
- Testing
- Conventional composite resin (3M™ Filtek™ Z350 XT Universal Restorative), Preheated composite resin (3M™ Filtek™ Z350 XT Universal Restorative)
- Where
- Malaysia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Manipal University College Malaysia
Cervical Cancer
Acceptability of Human Papillomavirus (HPV) Self-sampling Tools for Cervical Cancer Prevention
The proposed study aims to increase HPV screening behaviors in Jamaican women by examining the acceptability of HPV Deoxyribonucleic Acid (DNA) self-sampling tools, and to determine the most culturally appropriate and effective…
- Trial name
- NCT03613493
- Testing
- HPV self-sampling kit, Culturally-targeted Fear Appeal Message, Fear Appeal Message
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Miami
Failed Induction, Cervical Dystocia
Transvaginal Sonographic Measurement of Cervical Length Versus Bishop Score in Induction of Labour for Prediction of Caesarean Delivery.
Transvaginal sonographic measurement of cervical length versus Bishop score in labour induction at term for prediction of Caesarean delivery. This study is prospective study.
- Trial name
- NCT03430804
- Testing
- Bishop score calculation of modified Bishop score in numbers by digital vaginal examination
- Where
- Egypt
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nasopharyngeal Carcinoma
KSD-101 Therapy for Standard Treatment Failed EBV-associated NPC: an Exploratory Clinical Trial
The main purpse of this study is to evaluate the safety of KSD-101 in patients with EBV-associated Nasopharyngeal Carcinoma,to evaluate the initial clinical outcomes and evaluate the immune response to KSD-101 for the treatment…
- Trial name
- NCT06370026
- Testing
- KSD-101
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cancer, Cancer Metastatic
The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors
The purpose of this prospective, interventional, single-arm pilot study is to evaluate whether virtually delivered group-based physical activity is feasible for adolescent and young adult (AYA) cancer survivors.
- Conditions
- Cancer, Cancer Metastatic, Neoplasms, Breast Cancer
- Trial name
- NCT05131815
- Testing
- Virtual group based physical activity (BurnAlong) and Social Media Discussion Board
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Cancer of Head and Neck, Smoking
Assessment of Early Genetic Changes in Smokers
This study will look at the genetic profile of cells taken from the oral cavity of healthy college students who smoke and who do not smoke cigarettes.
- Trial name
- NCT00200408
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
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