Clinical trials: Neck Cancer
Esophagus Cancer
Neoadjuvant Chemoradiotherapy Combined With PD-1 Antibody in Locally Advanced Esophageal Cancer
This study will evaluate the safety and feasibility of preoperative immune checkpoint therapy with concurrent Chemoradiotherapy in patients with locally advanced esophageal squamous cell carcinoma.
- Trial name
- T+TP (NCT04177875)
- Testing
- Teripalimab
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Squamous Cell Carcinoma of the Head and Neck
Definitive Concurrent Hypofractionated Rth With Weekly Cisplatin in Locally Advanced SCCHN
The primary endpoint will be acute toxicity. Secondary endpoints included: late toxicity and quality of life; loco-regional control, disease free survival and overall survival.
- Trial name
- NCT03880396
- Testing
- hypofractionated Rth with platinol
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cervical Cancer
Decreasing Over Screening and Treatment of Cervical Precancers in Young Women
The goal of this study is to prevent over screening and over treatment of young women for cervical precancers, which can result in psychological distress and has been associated with future risk of premature deliveries.
- Trial name
- NCT02270021
- Testing
- Provider Mobile Application (ProvAPP), ProvAPP + Patient Educational Tool (Tab)
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cervical Dysplasia
A Pilot Study to Evaluate Ultrasonic Surgical Aspiration as a Treatment Modality for Cervical Dysplasia
Ultrasonic surgical aspiration of the cervix may be an effective method of treating cervical dysplasia without compromising the integrity of the cervix in reproductive age women.
- Trial name
- NCT00374114
- Testing
- cervical conization, ultrasonic surgical aspiration of the cervix
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Cervical Cancer Screening
Community-based Intervention for Cervical Cancer Screening Uptake in Nepal
This study aims to evaluate the effect of a Female Community Health Volunteer (FCHV) led community-based educational intervention through home visits increasing cervical cancer screening uptake.
- Trial name
- COBIN-C (NCT03808064)
- Testing
- FCHV home visit
- Where
- Nepal
- Volunteers
- 690 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cervical Cancer
Study on AUNIP as a Novel Tumor Marker for Cervical Cancer
To detect the expression of AUNIP in cervical cancer serum, and to clarify its diagnostic and prognostic value.
- Trial name
- NCT06118463
- Testing
- Detection of serum AUNIP expression
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lin Yuan
Health Status Unknown, Precancerous Condition
Self-Sampling in Women Who Do Not Undergo Routine Cervical Screening
RATIONALE: Women who do not undergo routine cervical screening may be more likely to collect a self-sample for human papillomavirus testing.
- Trial name
- NCT00977392
- Testing
- compliance monitoring, cervical Papanicolaou test, educational intervention
- Where
- United Kingdom
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Barts and the London School of Medicine and Dentistry
Head and Neck Cancer, Survivorship
The HEART Study (Healthy Eating and Recovery Together)
Head and neck cancer survivors and their primary caregivers (N=25 dyads) will be enrolled to pilot test a nutrition support system with a care planning clinic visit and a caregiver mobile App.
- Conditions
- Head and Neck Cancer, Survivorship, Nutrition Aspect of Cancer
- Trial name
- NCT04552587
- Testing
- Heart APP
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Esophageal Squamous Cell Carcinoma
Changhai Multimodal Esophageal Cancer Cohort
The burden of esophageal squamous cell carcinoma (ESCC) in China is substantial, with 85% of the cancers being in the progressive stage.
- Trial name
- CMECC (NCT06410677)
- Testing
- DNA Sequencing, RNA Sequencing
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wangluowei
Cervical Cancer
Non-invasive Biomarker Discovery for Pre-cervical or/and Cervical Cancer-HPV DNA and Other Biomarkers in Urine
The goal of this clinical trial is 1. To test the sensitivity and specificity of using HPV DNA from urine for the detection of pre-cervical or/and cervical cancer. 2.
- Trial name
- NCT06261892
- Testing
- Collect HPV DNA from urine
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- WomenX Biotech Limited
Liver Cancer, Anxiety Disorder
Early Palliative Care With Standard Care or Standard Care Alone in Improving Quality of Life of Patients With Incurable Lung or Non-colorectal Gastrointestinal Cancer and Their Family Caregivers
The study intervention consists of the early integration of palliative care services into standard oncology care in an outpatient setting for patients with advanced lung and non-colorectal gastrointestinal malignancies who are…
- Conditions
- Liver Cancer, Anxiety Disorder, Depression, Small Cell Lung Cancer
- Trial name
- NCT02349412
- Testing
- Early palliative care
- Where
- 23 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Cervical Cancer, Vulvar Cancer
Long-term Follow-up of Bivalent Human Papillomavirus (HPV) Vaccine Study in Women
This extension study aims to evaluate the long-term protection and immune response of the bivalent HPV vaccine in women aged 18-30 who participated in a previous efficacy study (311-HPV-1003).
- Conditions
- Cervical Cancer, Vulvar Cancer, Vaginal Cancer, CIN - Cervical Intraepithelial Neoplasia
- Trial name
- NCT06776055
- Testing
- HPV-16/18 vaccine
- Where
- 9 sites in China
- Volunteers
- 5,372 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Gynecologic Malignant Tumor
The Study of Massively Parallel Sequencing in Early Detection for Gynecologic Malignant Tumor
As human aging, 50% of women will be faced with the threat of cancer, especially gynecological malignancies. Ovarian, cervical and endometrial cancer are three major gynecological malignancies.
- Trial name
- NCT02166515
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhiqing, Liang
Cervical Cancer Screening, Cervical Cancer
Evaluation of Three Strategies Based on Vaginal Self-sampling Kit Send to Home of Unscreened Women for Cervical Cancer
Despite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths.
- Trial name
- APACHE-4 (NCT03856684)
- Testing
- Self-sampling kit sent at home, Self-sampling kit sent at home + SMS reminder, Letter offering a self-sampling kit "on request"+ SMS reminder
- Where
- France
- Volunteers
- 10,400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Oral Cavity Cancer
Risk Factors Contributing to Oral Cancer in Patients at Dr. Hasan Sadikin General Hospital Bandung
Analytical research with a cross-sectional approach was carried out on patients diagnosed with oral cavity cancer who visited our outpatient clinic in Bandung between 2023 and 2024.
- Trial name
- NCT06690918
- Where
- Indonesia
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
HPV Integration
The Predictive Role of HPV Integration in HSIL and Cervical Cancer
The stratified analysis by the level of HPV DNA integration in HSIL and cervical cancer will be drawn to explore whether the status of HPV integration makes any difference in the progression of cervical cancer.
- Trial name
- NCT05300243
- Testing
- HPV integration test
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Cervical Cancer
Intervention to Improve Follow-up of Abnormal Pap Test
This project will examine whether a theory-based telephone intervention delivered by a nurse at the time women are informed of an abnormal Pap test result will increase adherence to follow-up recommendations.
- Trial name
- NCT00575510
- Testing
- Intervention, Active control
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cervical Dysplasia
The Mother-Daughter Project: Merck-4
This project serves to continue a community-based initiative, known as the Kenya Mother-Daughter Cervical Cancer Eradication Project, or the Mother-Daughter Project (MDP), in the Webuye region of Western Kenya.
- Trial name
- Merck-4 (NCT07240220)
- Testing
- Gardisil-9, High Risk HPV DNA Testing, Visual Inspection with acetic acid (VIA) and possible cervical biopsy
- Where
- Kenya
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Indiana University
Barretts Esophagus, High Grade Dysplasia
Endoscopic Tri-Modal Imaging in Patients With Barrett's Esophagus
This study is being done to determine if a new endoscope will help doctors identify pre-cancer or early cancer lesions in patients who have Barrett's esophagus.
- Conditions
- Barretts Esophagus, High Grade Dysplasia, Early Esophageal Adenocarcinoma
- Trial name
- ETMI (NCT00586989)
- Testing
- Upper endoscopy with biopsy
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cervical Intraepithelial Neoplasia, Cervical Cancer
Dose-Ranging Study of Recombinant Human Papillomavirus Virus 16/18 Bivalent Vaccine
This is a phase II clinical study of the novel recombinant HPV 16/18 bivalent vaccine expressed in E. coli. The primary purpose of this study is to evaluate which dosage of the HPV vaccine can induce higher antibody and at the…
- Trial name
- NCT01356823
- Testing
- 30μg HPV, 60μg HPV, 90μg HPV
- Where
- China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Xiamen University
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