Clinical trials: Necrotizing Scleritis
Scleritis
Sirolimus Injections for Autoimmune Scleritis
Background: Autoimmune scleritis is an inflammatory disease that affects the white outer part of the eye. It is associated with immune system disorders like rheumatoid arthritis. It can cause blindness in severe cases.
- Trial name
- ISAS (NCT01517074)
- Testing
- Sirolimus
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Eye Institute (NEI)
Necrotizing Scleritis
Perichondrium Autograft in Refractory Necrotizing Scleritis
Necrotizing scleritis with severe ischemia is refractory to conventional treatment because of avascular necrosis. The investigators assessed the therapeutic efficacy and safety of autologous perichondrium transplantation in…
- Trial name
- PCRNS (NCT02864823)
- Testing
- Perichondrium Autografts
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Chung-Ang University Hospital
Non-infectious, Non-necrotizing Anterior Scleritis
Iontophoresis Delivery of Dexamethasone Phosphate for Non-infectious, Non-necrotizing Anterior Scleritis, Phase 1 Dose-varying Study
This is an initial clinical trial evaluating whether different doses of iontophoresis for delivery of dexamethasone phosphate can be tolerated by eyes of patients with non-infections, non-necrotizing scleritis.
- Trial name
- NCT01059955
- Testing
- Dexamethasone Phosphate Ophthalmic Solution (EGP-437), Dexamethasone phosphate ophthalmic solution
- Where
- 6 sites in United States
- Volunteers
- 18 people
- Sponsor
- John Kempen