Clinical trials: Needle Biopsy
Liver Biopsy
Liver Biopsy Using a 19 Gauge Fine Needle Biopsy Needle
A 19 gauge FNB needle, using same technique as with 22 gauge needle, to obtain liver histological specimen in regards to core length and the number of Complete Portal Triads.
- Trial name
- NCT03910790
- Testing
- 19 gauge needle liver biopsy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- AdventHealth
Pancreatic Cancer, Lymphadenopathy
Beacon BNX™ Endoscopic Ultrasound (EUS)-Needle vs SharkCore™ Needle
The primary objective of this proposed prospective randomized, multi-center study is to evaluate the capability of the new 22G SharkCore™ needle to obtain tissue specimens and to compare its performance against the standard 22G…
- Conditions
- Pancreatic Cancer, Lymphadenopathy, Cholangiocarcinoma
- Trial name
- NCT02872831
- Testing
- 22G SharkCore™ needle, 22G BNX EUS-FNA Needle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Diagnosis of Pleural Diseases
Image-guided Pleural Biopsy or Medical Thoracosocopy in Diagnosis of Pleural Disease
Pleural diseases can occur due to numerous pathological conditions. The increasing prevalence of etiologic causes and aging population worldwide will make pleural diseases a growing problem in the coming years.
- Trial name
- NCT05428891
- Testing
- Abrams' needle pleural biopsy (IG-ANPB) versus medical thoracoscopy in the diagnosis of pleural diseases.
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Pancreatic Neoplasm
Core Biopsy Endo Sonography Study Evaluation of the Significance of the Pro-core® Needle
The study is designed to evaluate the diagnostic accuracy of a new designed endoscopic ultrasonography (EUS) Core biopsy aspiration needle in comparison to a conventional EUS aspiration needle in GI-tumors.
- Trial name
- COS (NCT02181140)
- Testing
- EUS guided FNA and fine needle punction
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Breast Cancer
Accuracy of VABB Elite 10G Versus BARD 14G CNB
In this study, patients whose breast ultrasound showed a space-occupying lesion and needed biopsy to clarify the pathology were selected as the research subjects.
- Trial name
- NCT04612439
- Testing
- VABB Elite 10G, BARD 14G CNB
- Where
- China
- Volunteers
- 1,470 people, healthy volunteers welcome
- Sponsor
- Fudan University
Breast Cancer
Optical Spectroscopy During Breast Cancer Surgery and Core Needle Biopsy
The objective of the proposed research is to develop new diagnostic modalities based on optical spectroscopy (auto fluorescence, absorption, and scattering) for the diagnosis of breast cancer and test its performance as an…
- Trial name
- NCT00734838
- Testing
- High Resolution Microendoscope
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Duke University
Diagnoses Diseases, Ultrasound Therapy; Complications
19 Versus 22-Gauge Needle for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Conditions
- Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
- Trial name
- EUSLB1922 (NCT02967991)
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Cancer, Thyroid
Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules
This study will investigate the usefulness of an optical probe in the differentiation of thyroid cancer from normal thyroid tissue in a thyroidectomy specimen.
- Trial name
- NCT01401855
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Diagnostic Self Evaluation
Diagnostic Efficiency of Touch Imprints Versus Smears
Cytopathologists work along with radiologist in the diagnosis of lesions. Rapid on site interpretation (ROSE) of fine needle aspiration (FNA) smears of radiologically suspicious lesions is a common clinical practice.
- Trial name
- NCT03224910
- Testing
- Cytologic techniques used for rapid on site interpretation
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Prostate Cancer
Comparison Of Effectiveness of Transrectal Ultrasonography-Guided Saturation Biopsy And 10-12 Core Biopsy In Repeated Prostate Biopsies
OBJECTIVE To assessment the results of repeated saturation and 10-12 core biopsy protocols in patients with a negative initial biopsy but continued suspicion for prostate cancer MATERIALS AND METHOD Data of the patients who…
- Trial name
- NCT01827813
- Testing
- Transrectal prostate biopsy with ultrasonography., Periprostatic block, Sedoanalgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pneumothorax, Biopsy, Needle
CT-guided Lung Biopsy Risk Optimization Method
The purpose of this randomized controlled study is to evaluate the extent to which injection of a small amount of fluid in the pleural cavity at the biopsy site may reduce the risk of pneumothoraces, in addition to patient…
- Conditions
- Pneumothorax, Biopsy, Needle, Risk Factors, Radiology, Interventional
- Trial name
- BROM-I (NCT06340178)
- Testing
- Fluid application during ct-guided lung biopsy
- Where
- Switzerland
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Efficacy, Self
Diagnostic Efficacy Of 3 EUS-FNB Techniques
Endoscopic ultrasound (EUS) is a widely recognized tool for over 30 years for diagnosing intra-abdominal lesions and gastrointestinal cancers, especially pancreatic neoplasia.
- Trial name
- NCT05825729
- Testing
- Dry suction technique (A), Slow-pull technique (B), Wet suction technique (C)
- Where
- 2 sites in Spain
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Insular Gran Canaria
Prostate Cancer Diagnosis
Can Needle Size Improve Cancer Detection Rate of Transperineal MRI Target Prostate Biopsy Without Affecting Side Effects?
Differences in terms of diagnostic capability and side effects related to the needle caliber used for prostate biopsy sampling in patients with suspected prostate cancer
- Trial name
- TARGET (NCT06420115)
- Testing
- different needle size for prostate biopsy
- Where
- Italy
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Thyroid Nodule
Virtual Reality Glasses on Applied During Thyroid Fine Needle Aspiration Biopsy
The Effect of Virtual Reality Glasses on Applied During Thyroid Fine Needle Aspiration Biopsy on Anxiety Level, Pain Intensity and Patient Satisfaction
- Trial name
- NCT06823687
- Testing
- Virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Cancer of Pancreas, Cancer of Stomach
Wet Heparinized Suction for Abdominal Cancer
The purpose of this research is to compare the amount and quality of tissue obtained by EUS-FNB when the device is flushed with an anticoagulant or "blood thinner" vs.
- Conditions
- Cancer of Pancreas, Cancer of Stomach, Cancer of Esophagus, Cancer of Liver
- Trial name
- EUS Heparin (NCT05041335)
- Testing
- wet heparinzed suction, Microsieve, No heparin flush
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults
The purpose of this clinical trial is to find out whether one type of fish oil works better than another at improving metabolic health in people who are at high risk of developing type 2 diabetes.
- Conditions
- Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes / Type 2 Diabetes, Obesity & Overweight
- Trial name
- END-T2D (NCT07575438)
- Testing
- Fish Oil, Corn oil control
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- May Faraj, PDt, PhD
Prostate Cancer
Prostate Biopsy Access Needle & Needle Guide Feasibility Study
The objective of the study is to assess the design features of a modified stainless steel access needle (single use disposable) in a clinical setting and a disposable, single use, custom-made, polymer needle guide used in…
- Trial name
- STABLE (NCT02828839)
- Testing
- Access needle
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Perineologic