Clinical trials: Needs Assessment
Healthy Lifestyle
Connect-5 Needs Assessment Survey to Identify Healthy Lifestyle Requirements of a Rural Irish Community
This is an anonymous needs assessment survey of the population of an Irish urban town. We plan to collect anonymous survey data in order to better understand residents needs and to determine the desired functionality of a new…
- Trial name
- CONNECT-5 (NCT05109026)
- Where
- Ireland
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Bipolar Disorder Mania
Study to Evaluate the Efficacy and Safety of Aripiprazole Administered With Lithium or Valproate Over 12 Weeks in the Treatment of Mania in Bipolar I Disorder
The purpose of the study is to determine whether aripiprazole provides additional clinical benefit to patients with Bipolar I disorder when combined with lithium or valproate over 12 weeks.
- Trial name
- NCT00665366
- Testing
- Aripiprazole, Lithium, Valproate
- Where
- 73 sites in Austria, Czechia and 11 more
- Volunteers
- 493 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Cancer
Evaluation of a Symptom and Needs Assessment for Patients With Cancer
This is a quality improvement study that aims to improve on the timely identification and management of symptoms and supportive care needs in patients with cancer.
- Trial name
- NCT04014751
- Testing
- Symptom Monitoring Intervention
- Where
- United States
- Volunteers
- 1,166 people
- Sponsor
- Northwestern University
Atrial Fibrillation, Diastolic Dysfunction
Atrial Fibrillation: Chronic Beta-blocker Use Versus As-needed Rate Control Guided by Implantable Cardiac Monitor
The goal of this study is to test the feasibility of guiding as-needed pharmacological rate control of atrial fibrillation (AF) by implantable cardiac monitors and to assess the impact of continuous beta-blocker therapy versus…
- Conditions
- Atrial Fibrillation, Diastolic Dysfunction, HFpEF - Heart Failure With Preserved Ejection Fraction
- Trial name
- NCT05745337
- Testing
- As needed pharmacological rate control with beta-blocker (metoprolol tartrate, metoprolol succinate) or calcium channel blocker (diltiazem, verapamil)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Breast Cancer, Breast Neoplasms
Mental and Cognitive Health and Physical Activity in the Perioperative Breast Cancer Setting
This study evaluates the complex relationships between mental health, cognitive function, and physical activity before surgery in patients with stage I-III breast cancer.
- Conditions
- Breast Cancer, Breast Neoplasms, Cancer, Breast, Cancer of the Breast
- Trial name
- NCT06595901
- Testing
- Actigraph, Questionnaires, BrainBaseline application
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
Social Anxiety Disorder
Efficacy of BNC210 in Acute, As-needed Treatment of Anxiety in Social Anxiety Disorder - 1
The purpose of the study is to evaluate the effect of a single, acute dose of BNC210 compared to placebo on reducing the severity of anxiety provoked by a behavioral assessment task and measured using the Subjective Units of…
- Trial name
- AFFIRM-1 (NCT06510504)
- Testing
- 225 mg BNC210
- Where
- 21 sites in United States
- Volunteers
- 370 people
- Sponsor
- Bionomics Limited
Stress, Family
Evaluation of a Resiliency Program for Fathers of Children and Youth With Special Health Care Needs
Based on findings from our prior trials with parents of children with learning and attentional disabilities and parents of children with autism spectrum disorder (Kuhlthau et al., 2020; Park et al., 2020; IRB approved…
- Conditions
- Stress, Family, Fathers
- Trial name
- NCT05535348
- Testing
- Relaxation Response Resiliency Program for Father of CYSHCN
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts General Hospital
Cancers
Cancer Survivor Registry: The Breast Cancer M.A.P. (Mind Affects the Physical) Project
Cancer Survivor Registry: The Breast Cancer M.A. P. (Mind Affects the Physical M.A.P.) Project to identify and help us understand the emotional and social needs of breast cancer survivors.
- Trial name
- NCT01295658
- Where
- United States
- Volunteers
- 3,729 people, healthy volunteers welcome
- Sponsor
- Cancer Support Community, Research and Training Institute, Philadelphia
Autism Spectrum Disorders
Improving Participation of Autistic Children and Adolescents in the Habilitation Process
This project aims to explore the impact of a survey-based and a meeting-based needs assessment models on 7 to 17 year old autistic children's participation in the needs assessment process at the initial reception when enrolled at…
- Trial name
- IMPAC (NCT06381856)
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Örebro County
Quality of Life, General Anesthesia
Assessment of Changes in Oral Health-related Quality of Life , Oral Hygiene Status and Body Growth in CSHCN Following Dental Treatment Under General Anaesthesia
evaluation of the impact of dental treatment under GA on oral health-related quality of life (OHRQoL) in children with SHCN with severe dental caries with Assessment in change in oral health status and the impact on children's…
- Conditions
- Quality of Life, General Anesthesia, Children With Special Health Care Needs, Body Mass Index
- Trial name
- NCT04861675
- Testing
- Full mouth rehabilitation under general anaesethia
- Volunteers
- 10 people
- Sponsor
- Cairo University
Coping Skills, Healthcare Workers
Psychological Health, Coping Strategies and Preferences of Military COVID-19 Deployers
The proposed research study aims to better understand COVID deployer needs. The study, informally referred to as Project COPE, asks David Grant U.S.
- Conditions
- Coping Skills, Healthcare Workers, Covid19
- Trial name
- NCT04646642
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Primary Immuno-Deficiencies
Evaluation of the Efficacy of the Sequencing Method by Gene-panel
In order to accelerate the identification of genes responsibles of PID, and to improve the diagnosis of PID, the research team would like to validate a rapid and targeted method of high-throughput sequencing, on 301 genes, known…
- Trial name
- Génétique-DIH (NCT02954640)
- Testing
- Blood sampling
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Imagine Institute
Small Cell Lung Carcinoma
Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)
This study is a rolling arm study of investigational agents as monotherapy or in combination with pembrolizumab in participants with anti-programmed cell death 1 (PD-1)/ programmed cell death ligand 1 (PD-L1) refractory ES-SCLC…
- Trial name
- NCT04938817
- Testing
- coformulation pembrolizumab/quavonlimab, lenvatinib, MK-4830
- Where
- 48 sites in United States, Australia and 10 more
- Volunteers
- 110 people
- Sponsor
- Merck Sharp & Dohme LLC
Chronic Intestinal Failure, Small Intestine Disease
Perception of Needs of Patients With Chronic Intestinal Failure and Their Practitioners: a Qualitative Study
The SBS NEEDS Study is a qualitative transversal study aiming to describe and understand the needs and knowledge of patients with Chronic Intestinal Failure as well as the representations of their practitioners Chronic Intestinal…
- Trial name
- SBS-NEEDS (NCT04390633)
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Arterial Occlusive Diseases
Study of Alfimeprase's Ability to Dissolve Blood Clots in the Leg and Help Prevent the Need for Surgery
The purpose of this study is to directly compare the safety and efficacy of intra-thrombus alfimeprase 0.3 mg/kg with placebo in acute peripheral arterial occlusion (PAO) as measured by a 30 day open vascular free surgery rate.
- Trial name
- NCT00338585
- Testing
- alfimeprase
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- ARCA Biopharma, Inc.
Pain, Postoperative
Ibuprofen Versus Ibuprofen/Acetaminophen Postoperatively in Patients Needing Root Canal Therapy
Aim: The purpose of this study was to compare ibuprofen versus an ibuprofen/acetaminophen combination for postoperative pain control in patients requiring root canal treatment with a tooth that is painful to cold and biting.
- Trial name
- NCT03631433
- Testing
- Ibuprofen 600 mg, ibuprofen 600 mg and acetaminophen 650 mg
- Volunteers
- 102 people
- Sponsor
- Ohio State University
Cancer, Kidney Diseases
Patient Reported Unmet Needs for Function and Supportive Occupational- and Physiotherapy Rehabilitation Interventions
Purpose: To determine unmet functional needs in patients referred to the Palliative Care Unit at Rigshospitalet, Copenhagen University Hospital will be asked to fill out self reported questionnaires regarding problem intensity…
- Conditions
- Cancer, Kidney Diseases, Heart Failure, Neurologic Disorder
- Trial name
- NCT04066153
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Quality of Life
Assessment of Oral Health Related Quality of Life After Full Mouth Rehabilitation Under GA
To assess Oral health related quality of life (OHRQOL) after full mouth rehabilitation under GA in a group of Egyptian children with special healthcare need.
- Trial name
- NCT03497312
- Testing
- full mouth rehabilitation
- Volunteers
- 14 people
- Sponsor
- Cairo University
Chronic Obstructive Pulmonary Disease
Smartphone-based Self-management in COPD Patients: A Needs Assessment Survey
COPD patients often experience multiple symptoms (e.g. dyspnea, cough, and deteriorating quality of life) and have imposed a substantial economic and social burden on health care.
- Trial name
- NCT05151198
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Mental Disorder, Intellectual Disability
Mental Health Care Provision for Adults With Intellectual Disability and a Mental Disorder
Quality of mental health services provision for adults with intellectual disability and comorbid mental disorder is considered inadequate and therefore in need of further improvement.
- Trial name
- MEMENTA (NCT01695395)
- Where
- 3 sites in Germany
- Volunteers
- 371 people
- Sponsor
- Technische Universität Dresden