Clinical trials: Negative Behaviour Change
Behavior Problem
Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children
The goal of this clinical trial is to learn the effect of dexmedetomidine premedication in postoperative negative behavior changes in children compared to midazolam premedication.
- Trial name
- NCT06417125
- Testing
- Dexmedetomidine Hydrochloride, Midazolam, normal Saline
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Fujian Provincial Hospital
Hot Flushes, Night Sweats
Progesterone for Perimenopausal Night Sweats
The purpose of this study is to test whether a oral micronized progesterone reduces the Vasomotor Symptom Score comprised of the number and severity of hot flushes and night sweats in perimenopausal women.
- Trial name
- NCT01464697
- Testing
- Oral micronized progesterone
- Where
- Canada
- Volunteers
- 249 people
- Sponsor
- University of British Columbia
Depression, Unipolar, Anxiety Disorder Social
Trans-diagnostic Group CBT vs. Standard Group CBT for Depression, Social Anxiety and Agoraphobia/Panic Disorder
Transdiagnostic Cognitive Behavior Therapy (CBT) delivered in the individual format, have been proven just as effective as traditional diagnosis specific CBT manuals.
- Conditions
- Depression, Unipolar, Anxiety Disorder Social, Panic Disorder
- Trial name
- TRACT-RCT (NCT02954731)
- Testing
- UP-CBT, Standard-CBT
- Where
- 4 sites in Denmark
- Volunteers
- 292 people
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Negative Behaviour Change
Pilot Study: Intraoperative Clonidine and Postoperative Behaviour
Children who are upset during induction of general anaesthesia are frequently distressed postoperatively and are more likely to demonstrate negative behaviour changes.
- Trial name
- NCT02324413
- Testing
- Clonidine
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Richard Beringer
Cholera
Introduction of Cholera Vaccine in Bangladesh
The purpose of this study is to conduct and evaluate the feasibility and effectiveness of a mass cholera vaccination program to reduce diarrhea due to Vibrio cholerae in a high incidence urban area.
- Trial name
- ICVB (NCT01339845)
- Testing
- ShanChol, Vaccine and behaviour
- Where
- Bangladesh
- Volunteers
- 240,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Depression
Cognitive Bias Modification (CBM) and Internet Cognitive Behavioural Therapy (iCBT) for Depression- A Randomised Controlled Trial
Cognitive accounts of depression and anxiety emphasize the importance of cognitive biases in the maintenance of disorders. One specific bias is the interpretation of ambiguous information.
- Trial name
- NCT01488058
- Testing
- OxIGen + iCBT, Waitlist Control
- Where
- Australia
- Volunteers
- 69 people
- Sponsor
- Alishia Williams
Cognitive Change, Well-Being, Psychological
Acute Effects of Physical Activity on Cognition and Well-being in University Students
Previous studies in young adults have shown that physical activity can generate positive emotions and improve attention, among other cognitive functions.
- Trial name
- ActClass4Brain (NCT06168526)
- Testing
- Acute physical activity
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Behavior Problem
Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in Children
The goal of this clinical trial is to learn whether intranasal dexmedetomidine or esketamine given before anesthesia can reduce negative postoperative behavioral changes in children undergoing day surgery.
- Trial name
- PEDI-NPOBCs (NCT07570160)
- Testing
- Dexmedetomidine, Esketamine, Normal Saline
- Where
- China
- Volunteers
- 342 people
- Sponsor
- Nanjing Children's Hospital
Alcohol Use, Drug Use
Trial of an Adapted STD Screening and Risk Reduction Intervention
The goal of this research study is to evaluate the impact of a paraprofessional-delivered, culturally adapted, evidence-based intervention (EBI) on sexually transmitted disease (STD), substance use and poor mental/emotional…
- Conditions
- Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea
- Trial name
- NCT02513225
- Testing
- Project EMPWR, Optimized Standard Care (OSC)
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Sexually Transmitted Infections
STI/HIV Intervention Behavioral Intervention Program
The hypothesis is that a behavioral intervention tool adapted for the US military population will be acceptable and associated with a decrease in incident sexually transmitted infection (STI)/HIV rates and high-risk sexual…
- Trial name
- NCT04547413
- Testing
- STI/HIV Intervention Behavioral Intervention Program
- Where
- 2 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Social Anxiety
Enhancing Psychological Self-help With Implementation Intentions
Individuals with visible conditions often report experiencing lowered social confidence and encountering intrusive reactions from others, yet relatively few targeted psychosocial self help interventions are available.
- Trial name
- NCT03004027
- Testing
- Self help leaflet
- Where
- United Kingdom
- Volunteers
- 326 people
- Sponsor
- University of Sheffield
Disordered Eating Behaviors, Binge Eating
Enhanced Cue Exposure Therapy for Negative Emotional Eating
The current study aims to evaluate the efficacy of Enhanced Cue Exposure Therapy (E-CET) in reducing negative emotional eating (NEE), compared to an active control intervention, behavioral lifestyle intervention (BLI), in a…
- Trial name
- NCT06012045
- Testing
- Enhanced Cue Exposure Therapy, Behavioral Lifestyle Intervention
- Where
- Hong Kong
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong
Trauma, Brain, Brain Injuries
Intervention to Change Attributions That Are Negative (ICAN)
ICAN is the first treatment to target hostile attributions after TBI, making it a novel anger/ aggression management approach in this population. This is a randomized waitlist control trial.
- Conditions
- Trauma, Brain, Brain Injuries, Traumatic Brain Injury, Brain Injuries, Traumatic
- Trial name
- ICAN (NCT03648476)
- Testing
- ICAN
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Indiana University
Cholera
Water, Sanitation, and Hygiene Mobile Health Messages as an Innovative Tool to Facilitate Behavior Change
Develop a scalable approach for delivering water, sanitation, and hygiene (WASH) messages to households in areas with confirmed cholera patients in Dhaka, Bangladesh.
- Trial name
- CHoBI7 (NCT04816552)
- Testing
- CHoBI7 mHealth program Arm, general message on oral rehydration solution (ORS)
- Where
- Bangladesh
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Diabetes Mellitus, Type 2
Lifestyle Modification for Type 2 Diabetes Involving Reduction of After-meal Blood Glucose Elevations
The purpose of this study is to determine if a lifestyle modification program (GEM) that focuses on reducing after-meal blood glucose elevations can improve blood glucose control in people with type 2 diabetes.
- Trial name
- NCT02432391
- Testing
- GEM
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Virginia
Autism Spectrum Disorder
The Effects of Preoperative Intranasal Administration of Dexmedetomidine and Esketamine on Negative Postoperative Behavioral Changes in Children With Autism Spectrum Disorder
The goal of this clinical trial is to learn whether intranasal sedation given before anesthesia can lower negative postoperative behavioral changes in children with autism spectrum disorder who undergo elective surgery.
- Trial name
- NPOBCs (NCT07324057)
- Testing
- Intranasal dexmedetomidine, Intranasal Esketamine, saline control
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Sun Fei
Anxiety Disorders, Depressive Disorder
Big Feelings: A Study on Children's Emotions in Therapy
The goal of this clinical trial is to learn about how psychotherapy works for children and adolescents aged 8 - 15 with anxiety, depression, trauma, or disruptive behaviour.
- Conditions
- Anxiety Disorders, Depressive Disorder, Mood Disorders, Conduct Disorder
- Trial name
- NCT05637320
- Testing
- Modular Approach to Therapy for Children with Anxiety, Depression, Trauma or Conduct Problems
- Where
- 2 sites in Canada
- Volunteers
- 202 people
- Sponsor
- University of Guelph
Behavior, Child, Anxiety
Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department
The purpose of this study is to evaluate if a virtual reality (VR) distraction game played prior to procedural sedation for long bone fracture reduction will improve post-discharge negative behavior changes following discharge…
- Trial name
- NCT03980067
- Testing
- Virtual Reality Game
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Medical College of Wisconsin
Exercise Addiction, Diet Habit
Dietary Choice in Active Older Adult Women
The present study aimed to determine the effects of negative-calorie diet supplemented with exercise, on weight loss and lipid profile, and to compare its efficiency with low-calorie diet with exercise among elderly adult women…
- Conditions
- Exercise Addiction, Diet Habit, Obesity, Overweight
- Trial name
- NCT03082781
- Testing
- NCDsport, LCDsport
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Body Weight Changes, Human Immunodeficiency Virus
Doravirine and Weight Gain in Antiretroviral Naive
The purpose of this study is determine whether different antiretroviral therapy (ART) changes the effects on body fat and predict the weight change in Black and Hispanic females.
- Conditions
- Body Weight Changes, Human Immunodeficiency Virus, ART, Obesity
- Trial name
- DAWN (NCT05457530)
- Testing
- DOR/3TC/TDF, DOR + FTC/TAF, BIC/FTC/TAF
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Prism Health North Texas