Clinical trials: Neglected Diseases
Child Abuse, Child Neglect
Child-Parent Psychotherapy - a Feasibility Study for Children in Foster Care
Children in foster care have an increased risk of exposure to adverse experiences during childhood and across the lifespan. In current studies of interventions children in foster care are often excluded, or they are too few to be…
- Conditions
- Child Abuse, Child Neglect, Post-Traumatic Stress Disorder in Children, Parent-Child Relations
- Trial name
- NCT04519229
- Testing
- Child-Parent Psychotherapy
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Kronoberg County Council
Rheumatic Diseases, Abuse Neglect
Prevalence of Abuse Among Patients With Rheumatic Diseases
Patients with rheumatic diseases (RD) have a relevant representation in the adult population in Mexico. RD are characterized by their chronic and progressive nature, which can impact functionality during the disease and can…
- Conditions
- Rheumatic Diseases, Abuse Neglect, Abuse
- Trial name
- NCT06233760
- Testing
- Rheumatic diseases Mistreatment Scale (RDMS), Health Assessment Questionnaire (HAQ), Depression, Anxiety and Stress Scale (DASS-21)
- Where
- Mexico
- Volunteers
- 244 people
- Sponsor
- National Institute of Medical Sciences and Nutrition, Salvador Zubiran
Chronic Kidney Diseases, Diabetes Mellitus
Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa
Prospective cross-sectional study at the outpatient clinic (OPC) of the Bagamoyo District Hospital (BDH) in Tanzania. Assessment of basic epidemiological data (Point prevalence and risk factors) on CKD with simple clinical…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, Hypertension, Tuberculosis
- Trial name
- RenalOne (NCT03458338)
- Testing
- estimated glomerular filtration rate and albuminuria
- Where
- Switzerland
- Volunteers
- 1,006 people
- Sponsor
- University Hospital, Basel, Switzerland
Hemodialysis Complication, Stress Disorders, Post-Traumatic
The Effect of Roy Adaptation-Based Nursing Intervention
Abstract Objective: The research was conducted to determine the effect of the nursing intervention, which was given to patients according to the Roy Adaptation Model, on patients' stress, psychosocial adjustment, and self-care…
- Conditions
- Hemodialysis Complication, Stress Disorders, Post-Traumatic, Psychosocial Impairment, Self Neglect
- Trial name
- NCT05568342
- Testing
- The Effect of Roy Adaptation-Based Nursing Intervention on Stress, Psychosocial Adjustment and Self-Care Power in Hemodialysis Patients: A Randomized Controlled Experimental Study
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep Islam Science and Technology University
Neglect, Hemispatial, Stroke Acute
Multisensory Integration and Cognitive Awareness in Post-Stroke Unilateral Spatial Neglect
The primary aim of this study is to investigate whether multisensory integration (MSI) mechanisms observed in patients with right hemisphere lesions without neglect remain intact compared to patients with Unilateral Spatial…
- Trial name
- NCT06690125
- Testing
- Classical and computerized assessment
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Universita di Verona
Platelet Levels and Mean Platelet Volume in Patients With CF
Platelets in Cystic Fibrosis Lung Inflammation
Cystic fibrosis (CF) is a chronic multiorgan disorder caused by mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene.
- Trial name
- NCT05339724
- Testing
- platelet count and mean platelet volume are obtained from whole blood count
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Mersin Training and Research Hospital
Stroke, Acute Stroke
Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC)
The goal of this clinical trial is to evaluate whether a multicomponent nurse-led intervention (BEST CARE ICTUS_HC) can reduce stroke-related complications and improve recovery in adults (18 years and older) hospitalized with an…
- Conditions
- Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- BESTCAREICTUS (NCT07627399)
- Testing
- BEST CARE ICTUS_HC BUNDLE
- Where
- 4 sites in Spain
- Volunteers
- 700 people
- Sponsor
- University of Malaga
Opioid Use Disorder, Neonatal Abstinence Syndrome
RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure
The impact of parental opioid use disorder and other substance use exposure on child welfare and the healthcare system is undeniable.
- Conditions
- Opioid Use Disorder, Neonatal Abstinence Syndrome, Child Development, Child Abuse
- Trial name
- RESPECT-Plus (NCT02334111)
- Testing
- RESPECT-Plus
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Medical Center
Hookworm Infection, Hookworm Disease
Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults
Na-GST-1 is a protein expressed during the adult stage of the Necator americanus hookworm life cycle that is thought to play a role in the parasite's degradation of host hemoglobin for use as an energy source.
- Trial name
- NCT03373214
- Testing
- Na-GST-1, CPG 10104
- Where
- Gabon
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Healthy Volunteers
First in Man Clinical Trial of Emodepside (BAY 44-4400)
This study will investigate the safety, tolerability, and pharmacokinetics of single ascending doses of emodepside (BAY 44-4400) in healthy male volunteers.
- Trial name
- NCT02661178
- Testing
- emodepside (BAY 44-4400)
- Where
- United Kingdom
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Drugs for Neglected Diseases
Stroke
Feasibility of Measuring Vertical Perception in Acute Stroke
The goal of this observational study is to establish if it is feasible to identify vertical perception deficits in people with acute stroke.
- Trial name
- NCT06301815
- Testing
- Scale for Contraversive Pushing, Catherine Bergego Scale, Bucket Test
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- University of Winchester
Spatial Neglect
Dosing and Deployment Trial: A Home-based Optokinetic Treatment
Several interventions exist for remediation of spatial neglect, but they have mixed evidence. Optokinetic stimulation is a bottom-up intervention; in other words, it is a stimulus-driven process, with Level A (strongest)…
- Trial name
- NCT07519317
- Testing
- Optokinetic stimulation
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Duke University
Stroke, Acquired Brain Injury
Remediation of Spatial Neglect Trial
Problems with attention are a common and debilitating consequence of brain injury. Studies show that poor attention is the number one predictor of poor cognitive functioning one year post-injury.
- Conditions
- Stroke, Acquired Brain Injury, Hemispatial Neglect
- Trial name
- RESPONSE (NCT01965951)
- Testing
- Computerized Plasticity-based Adaptive Cognitive Training, Commercially available computerized training
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Posit Science Corporation
Substance Use
Brief Intervention in At-Risk First-time Mothers
Preliminary controlled trial of a brief intervention designed to reduce child maltreatment risk among low-income pregnant mothers.
- Trial name
- NCT00230009
- Testing
- Brief motivational intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Sensory Neglect, Stroke
Feasibility and Effectiveness Study of Implementing Prism Adaptation as a Treatment for Spatial Neglect After Stroke
Spatial neglect is a common attention disorder after right hemisphere stroke and is associated with decreased independence and quality of life.
- Trial name
- NCT02680171
- Testing
- Prism Goggles, Non-Shifting Goggles
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Nova Scotia Health Authority
Neglect, Hemispatial, Stroke, Cardiovascular
Implementation of IVS3 for Upper Limb Motor Recovery
This study measures participant satisfaction and upper extremity function in outpatients with chronic stroke when exposed to the IVS3 device.
- Conditions
- Neglect, Hemispatial, Stroke, Cardiovascular, Mirror Movement, Motor Activity
- Trial name
- NCT06483230
- Testing
- Intensive Visual Stimulation Device
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Weill Medical College of Cornell University
Onchocerciasis, Ascaris Lumbricoides Infection
Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases
This clinical trial compares two treatments - ivermectin and moxidectin - to learn which is better at reducing the proportion of people with onchocerciasis (river blindness) when given through mass drug administration (MDA) in…
- Conditions
- Onchocerciasis, Ascaris Lumbricoides Infection, Trichuris Trichiura; Infection, Hookworm Infections
- Trial name
- EKAIO (NCT07145736)
- Testing
- Moxidectin, Ivermectin
- Where
- Angola
- Volunteers
- 52,000 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Stroke
NonInvasive Brain Stimulation in Stroke Patients
After a stroke affecting the right side of the brain, many patients are affected by "spatial neglect": the damage to the brain causes them to ignore the left side of their surroundings.
- Trial name
- RTNIBS (NCT02401724)
- Testing
- Transcranial direct current stimulation, Action Training
- Volunteers
- 60 people
- Sponsor
- NHS Greater Glasgow and Clyde
Stroke, Hemispatial Neglect
Examining Measurement of Behavioral Neglect Post Stroke
The purpose of this study is to examine measurement of unilateral neglect post stroke. Although a number of clinical assessments are used to measure neglect, it is unclear whether items from some of the most commonly used…
- Trial name
- NCT02935270
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Medical University of South Carolina
Hemispatial Neglect, Hemiplegia
The Effects of Offline Anosognosia For Spatial Neglect on Neglect Rehabilitation
Anosognosia for hemispatial neglect is an intriguing phenomenon characterized by decreased awareness of spatial deficits, common in patients with right hemisphere stroke.
- Conditions
- Hemispatial Neglect, Hemiplegia, Right Hemispheric Stroke, Anosognosia
- Trial name
- NCT05145855
- Testing
- Patient-tailored multimodal neglect rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Gazi University