Clinical trials: Neoadjuvant Chemoradiotherapy
Breast Cancer Female
Effect of Neoadjuvant Chemoradiation on Pathologic Complete Response Rates in Locally Advanced Breast Cancer Patients
This is a phase II randomized trial comparing pathologic complete response rates in locally advanced patients recieving either neoadjuvant chemotherapy or neoadjuvant chemoradiation.
- Trial name
- NCT06631066
- Testing
- neoadjuvant chemoradiation
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Neoadjuvant Chemoradiotherapy, Rectal Tumor
Outcomes of Resection at Different Times Between the End of Neoadjuvant Treatment and Surgery
Neoadjuvant radio-chemotherapy (NRCT) represents a milestone in the treatment of selected rectal tumours. Ideal time interval between the end of NRCT and surgery is still debated; a 6-8 weeks time interval is considered optimal…
- Conditions
- Neoadjuvant Chemoradiotherapy, Rectal Tumor, Surgery, Surgery--Complications
- Trial name
- NCT04013347
- Testing
- Rectal Resection
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Campus Bio-Medico University
Rectal Cancer
Additional Chemotherapy After Neoadjuvant Chemoradiotherapy in Patients With Locally Advanced Rectal Cancer
The aim of this study is to evaluate the efficacy and safety of additional neoadjuvant chemotherapy with capecitabine during the resting periods in patients with locally advanced rectal cancer.
- Trial name
- NCT01671683
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chungnam National University
Esophageal Cancer
The Efficacy of Neoadjuvant Chemoradiotherapy in Comparison With Neoadjuvant Chemotherapy in Patients With Resectable Squamous Cell Esophageal Cancer
The purpose of this study is to evaluate the safety, feasibility and outcomes of neoadjuvant chemotherapy followed by esophagectomy versus neoadjuvant chemoradiotherapy followed by esophagectomy for locally advanced resectable…
- Trial name
- NCT05547529
- Testing
- Patients undergoing neoadjuvant chemoradiotherapy plus Ivory-Lewis or McKeown esophagectomy., Patients undergoing neoadjuvant chemotherapy plus Ivory-Lewis or McKeown esophagectomy
- Where
- Russia
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Blokhin's Russian Cancer Research Center
Nasopharyngeal Carcinoma
Study of Chemoradiotherapy Combined With Cetuximab in Nasopharyngeal Carcinoma
This is an open, multicenter phase Ⅱ clinical trial. The purpose of this study is to evaluate acute toxicity and efficacy of cetuximab (C225) combined with IMRT + neoadjuvant chemotherapy in advanced T stage of nasopharyngeal…
- Trial name
- REPLACE (NCT01271439)
- Testing
- Cetuximab
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Rectal Cancer
Neoadjuvant Chemoradiation With RHUMAB VEGF (Avastin) for Rectal Cancer
Preoperative chemoradiation leads to increased pelvic control and overall survival, but both distant and local disease control remain problematic in locally advanced rectal cancer patients.
- Trial name
- NCT00113230
- Testing
- Avastin (Bevacizumab, RHUMAB VEGF), Capecitabine, Radiation Therapy
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Neoadjuvant Chemoradiotherapy
Hyperpolarized 13C-MRI and Radiomics in Rectal Cancer
This study is testing new imaging and analysis methods to improve how doctors predict treatment response in rectal cancer patients receiving chemoradiotherapy.
- Trial name
- DNP_RECA (NCT07730541)
- Testing
- Hyperpolarized 13C-MRI (HP 13C-MRI)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Rectal Cancer
Relationship Between Lymph Node Ratio and Survival Rate in Preoperative Chemoradiation Rectal Cancer Patients
Colorectal cancer is the most-common cancer of the gastrointestinal tract. The number of positive lymph nodes and total number of lymph nodes retrieved are important prognostic factors.
- Trial name
- NCT04096118
- Where
- Thailand
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Rectal Neoplasms
Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer
Given the growing focus on preserving organ function and the utilization of neoadjuvant therapy, it is important to investigate and enhance the application of comprehensive neoadjuvant therapy in low rectal cancer.
- Trial name
- NCT06417476
- Testing
- Short-course radiotherapy, Irinotecan, Oxaliplatin
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Pei-Rong Ding
Esophagus Cancer
Neoadjuvant Chemoradiotherapy Combined With PD-1 Antibody in Locally Advanced Esophageal Cancer
This study will evaluate the safety and feasibility of preoperative immune checkpoint therapy with concurrent Chemoradiotherapy in patients with locally advanced esophageal squamous cell carcinoma.
- Trial name
- T+TP (NCT04177875)
- Testing
- Teripalimab
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital