Clinical trials: Neonatal Outcome
Congenital Heart Disease
Nutritional Prehabilitation Program and Cardiac Surgery Outcome in Pediatrics
Nutritional Prehabilitation Program and Cardiac Surgery Outcome in Pediatrics. A randomized controlled trial.
- Trial name
- NCT02475759
- Testing
- Nutritional perioperative prehabilitation program for two weeks, Nutritional perioperative prehabilitation program for one week
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Ain Shams University
Neonatal Respiratory Distress
Vaginal Misoprostol to Improve the Neonatal Respiratory Outcome
Project summary: Objective: To test the hypothesis that administration of vaginal Misoprostol before elective cesarean section will improve the neonatal respiratory outcomes in late preterm and early term neonates through…
- Trial name
- NCT03239327
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 292 people
- Sponsor
- Assiut University
Dialysis, Fistula
Ultrasound Assisted Puncture of AV Fistulas in Chronic Hemodialysis Patients
The puncture of the vascular access in hemodialysis patients remains challenging even in the hands of experienced dialysis nurses.
- Trial name
- NCT02085486
- Testing
- Ultrasound-assisted puncture, Standard
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Duchenne Muscular Dystrophy
Outcome Measures in Duchenne Muscular Dystrophy: A Natural History Study
Novel emerging therapies for Duchenne Muscular Dystrophy (DMD) require a deeper understanding of DMD natural history. This study aim to assess the natural history of DMD through a composite assessment tool capable of capturing…
- Trial name
- NCT02780492
- Testing
- Set of assessment tools
- Where
- 5 sites in France, Netherlands and 1 more
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University College, London
Fetal Growth Restriction (FGR), Preeclampsia
Association of Assisted Reproductive Technologies Parameters With the Perinatal Outcome
The goal of this prospective cohort study is to examine how different parameters of assisted reproductive technologies (ART) are associated with the perinatal outcome in individuals with singleton or multiple gestations.
- Conditions
- Fetal Growth Restriction (FGR), Preeclampsia, Stillbirth, Placenta Previa
- Trial name
- NCT06918236
- Where
- 6 sites in Bulgaria, Greece and 1 more
- Volunteers
- 12,084 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Psoriasis, Eczema/Atopic Dermatitis
Skin-in-Sight: a Longitudinal Cohort Infrastructure for Standardized Remote Monitoring and the Evaluation of Digital Care Innovations in Chronic Skin Diseases
Psoriasis, atopic dermatitis (eczema) and hidradenitis suppurativa are long-term skin conditions that flare and settle over time. Most of what happens to the skin happens at home, between hospital appointments.
- Conditions
- Psoriasis, Eczema/Atopic Dermatitis, Hidradenitis Suppurativa (HS)
- Trial name
- Skin-in-Sight (NCT07804134)
- Where
- 3 sites in Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Medisch Spectrum Twente
Congenital Heart Disease
Bosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac Surgery
Cardiac surgery relieves symptoms and increases life expectancy in cardiac patients, with and without congenital heart disease (CHD).
- Trial name
- BOCA (NCT01184404)
- Testing
- Bosentan
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Berto J Bouma
Cleft Lip and Palate, Growth and Development
Efficacy of Maxillo-facial Treatment on Cleft Lip and Palate Patients Faces: Aesthetic Considerations
The aim of the study is to analyze the esthetic outcome of the first surgical repair of cleft lip and palate (CLP) patients. The aim of the study is to identify differences in the aesthetic evaluation of full-face and nasolabial…
- Conditions
- Cleft Lip and Palate, Growth and Development, Cicatrix, Randomized Controlled Trial
- Trial name
- NCT03395015
- Testing
- VAS scale (from 1 to 10) esthetic assessment of facial 3-D images
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Placenta Accreta
Pulmonary Artery Doppler and Neonatal Outcome in Placenta Accreta Spectrum Patients
To correlate ultrasonographic markers of fetal lung maturity including Pulmonary artery Doppler indices in the late preterm and early term in placenta accreta spectrum patients with neonatal outcome.
- Trial name
- NCT04911322
- Testing
- ultrasonography
- Where
- Egypt
- Volunteers
- 71 people
- Sponsor
- Cairo University
Infant, Newborn
Minipuberty and Its Effects on Preterm Neonates
It is generally known that there are some hormonal changes during puberty, but the knowledge about the activation of the same hormonal axis in the first months of life is relatively recent and it is not completely understood.
- Trial name
- NCT03858127
- Testing
- Collection of urine sample, Examination of genitalia, Video messaging
- Volunteers
- 20 people
- Sponsor
- NHS Greater Glasgow and Clyde
Newborn Health Complications, Maternal Health Complications
Encouraging Pregnant Women to Use Skilled Birth Attendants and Its Effects on Maternal and Newborn Health in Rural Bangladesh
The goal of this clinical trial is to learn whether encouraging pregnant women in rural Bangladesh to use a skilled birth attendant during childbirth can improve the health of mothers and newborns.
- Trial name
- NCT07804069
- Testing
- Skilled Birth Attendant Encouragement Intervention
- Where
- Bangladesh
- Volunteers
- 504 people
- Sponsor
- Hiroshima University
Pre-Eclampsia
Maternal and Neonatal Outcome in Severe Preeclampsia
In normal pregnancy the spiral arteries in the placental bed are invaded by trophoblast, which becomes incorporated into the vessel wall and replaces the endothelium, muscular layer and neural tissue
- Trial name
- NCT04126122
- Testing
- Ultrasonography to assess fetus and mother
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Biliary Atresia
Outcome of Kasai Portoenterostomy in Biliary Atresia in Upper Egypt
Kasai portoenterostomy is the key standard operation for biliary atresia. The aim of the study is to evaluate the short-term outcome of Kasai portoenterostomy for biliary atresia infants in Upper Egypt.
- Trial name
- NCT05925543
- Testing
- Kasai portoenterostomy operation.
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Aswan University Hospital
Protein C Deficiency
Retrospective Study to Capture Dosing and Treatment Outcome Data in Participants With Severe Congenital Protein C Deficiency Who Were Treated With Protein C Concentrate Under an Emergency Use IND
This is a data collection study with the purpose of capturing dosing and treatment outcome data in participants with severe congenital protein C deficiency who were treated with protein C concentrate under an Emergency Use…
- Trial name
- NCT00161720
- Testing
- Protein C Concentrate (Human) Vapor Heated
- Where
- 10 sites in United States
- Volunteers
- 11 people
- Sponsor
- Baxalta now part of Shire
Umbilical Cord Issue, Intrauterine Growth Restriction
Three-dimensional Umbilical Cord Coiling Index
Previous studies have shown that abnormal coiling of the umbilical cord is associated with adverse perinatal outcome. For example, an umbilical cord that is non-coiled increases the chance of fetal morbidity and mortality…
- Conditions
- Umbilical Cord Issue, Intrauterine Growth Restriction, Fetal Distress
- Trial name
- NCT05727241
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Fetal Growth Retardation
SLE Therapy Changes in Pregnancy and Relation to Pregnancy Outcome
to review the changes to SLE medications during pregnancy including adherence and non-adherence to the medications and correlate these to the pregnancy outcome and post-partum course of the disease.
- Trial name
- NCT05176041
- Testing
- Naser Al-Husban
- Volunteers
- 156 people
- Sponsor
- University of Jordan
Diabetes Mellitus, Type 1
Middle Cerebral and Umbilical Arteries Doppler Indices in the Prediction of Adverse Neonatal Outcome Among Diabetic Pregnant Women
120 patients will be included and divided into two groups; Control group that will include 60 healthy pregnant women and Study group that will include 60 pregestational diabetic pregnant patients which furtherly will be…
- Trial name
- NCT03915990
- Testing
- umbilical and middle cerebral artery Doppler
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Propionic Acidemia, Methylmalonic Acidemia
Long-term Outcome of N-Carbamylglutamate Treatment in Propionic Acidemia and Methylmalonic Acidemia
Background: Very few drugs exist that treat hyperammonemia, specifically PA and MMA. Diet restrictions and alternate pathway agents are the current primary treatments, but they frequently fail to prohibit brain damage.
- Trial name
- NCT01597440
- Testing
- N-carbamylglutamate, Standard of Care
- Where
- 7 sites in United States
- Volunteers
- 1 people
- Sponsor
- Mendel Tuchman
Gestational Diabetes Mellitus in Pregnancy
Adding Metformin to Insulin in Controlling Pregestational and Gestational Diabetes Mellitus
The purpose of the study to prove benefits of adding metformin to insulin for controlling presentational and gestational diabetes mellitus and improving neonatal outcome.
- Trial name
- NCT03106870
- Testing
- Insulin Mixtard, Metformin
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pregnancy, Pregnancy Complications
PregSource: Crowdsourcing to Understand Pregnancy
PregSource uses a crowd-sourcing approach, asking pregnant women to enter information regularly and directly about their pregnancies throughout gestation and the early infancy of their babies into online surveys and trackers via…
- Conditions
- Pregnancy, Pregnancy Complications, Morning Sickness, Diabetes, Gestational
- Trial name
- PregSource (NCT02577536)
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 2,359 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)