Clinical trials: Neonatal Pain
Neonatal Pain
ShotBlocker During Intramuscular Injection Randomized Control Trial
The objective of this trial is to evaluate the effect of Bionix ShotBlocker on pain of injection of the first Hepatitis B vaccine in healthy newborns.
- Trial name
- NCT06624176
- Testing
- Bionix ShotBlocker, Swaddling, Sucrose administration
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lauren Fortier
Procedural Pain, Neonatal Hyperbilirubinemia
The Effect of Kangaroo Care on Pain in Infants Receiving Phototherapy
This study aims to evaluate and compare the effects of two different kangaroo care (KC) models on pain management in neonates undergoing phototherapy.
- Trial name
- NCT07761689
- Testing
- Kangaroo Care, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
Neonatal Pain, Stress, Psychological
MOTHER3SENSE Study
This randomized controlled trial aims to compare the effects of maternal voice, touch, and scent on pain and stress levels in newborns during a routine heel lance procedure.
- Trial name
- MOTHER3SENSE (NCT07651592)
- Testing
- Maternal Voice, Maternal Touch, Maternal Scent
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Pain Management, Pain Assessment
Effectiveness and Implementation of a Clinical Pain Management Dashboard for the NICU
This study protocol describes a type 1 hybrid effectiveness-implementation study evaluating a clinical decision support dashboard for neonatal pain management in a tertiary NICU.
- Conditions
- Pain Management, Pain Assessment, Neonatal Intensive Care, Implementation Research
- Trial name
- NCT07629661
- Testing
- Implementation of clinical pain management dashboard
- Where
- Netherlands
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Neonatal, Pain Management
The Effect of Scents Applied During Heel Blood Collection on Newborn Crying Duration, Pain, and Physiological Parameters
One of the most common and painful procedures in newborns is taking a capillary blood sample from the heel. This basic procedure, widely used in early health assessments, particularly in newborn screening tests, can cause mild to…
- Trial name
- Randomized (NCT07350980)
- Testing
- oil
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Neonatal Pain, Non-Pharmacological Pain Management
Effect of Two Non-pharmacological Method on Pain, Stress Procedure Duration in Newborn
This study is planned as a prospective, single-blind, randomized controlled experimental study matched according to gestational age, gender, and birth weight, to determine the effects of local heat application and oral sucrose…
- Trial name
- NCT07125690
- Testing
- local heat application, oral sucrose, mixed group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Fear of Childbirth, Neonatal
Consequences of Admission to the Delivery Room in the Early and Late Phases
This study will be conducted to compare maternal and neonatal outcomes of pregnant women who applied to the delivery room in the early (latent) and late (active) phase.
- Conditions
- Fear of Childbirth, Neonatal, Pain, Maternal Distress (During Labor)
- Trial name
- NCT06344741
- Testing
- Accepted in latent phase, Accepted in active phase
- Where
- Turkey (Türkiye)
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Neonatal Disease, Neonatal Disorder
Reducing Pain and Promoting Neurodevelopment Among Preterm Neonates
To determine the effects of multisensory stimulation and soft tissue therapy on procedural pain and neurodevelopment among neonates admitted to the NICU is the aim of the study.
- Trial name
- NCT04366102
- Testing
- Multisensory stimulation with soft tissue therapy, Routine hospital care
- Where
- India
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Neonatal, Pain
The Effect of Music, White Noise and Heart Sound on Neonatal Pain
Infants are exposed to many painful procedures during their stay in the Neonatal Intensive Care Unit (NICU). Some epidemiological studies report that infants experience an average of 7.5-14 painful procedures per day per infant…
- Trial name
- NCT05828420
- Testing
- White noise, Heart sound, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Childbirth Problems, Labor Pain
The Effect of Birth Ball Exercise on Labor Pain, Delivery Duration, Birth Comfort, and Birth Satisfaction
It has been reported that the birth ball has benefits such as decreasing the perception of labor pain, reducing the anxiety level, shortening the duration of the first stage of labor, increasing the satisfaction of birth, and…
- Conditions
- Childbirth Problems, Labor Pain, Birth Disorder
- Trial name
- BB (NCT05711472)
- Testing
- birth ball exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Neonatal Disease, Pain, Acute
The Role of Time Interval Elimination on Pain Control of Preterm Infants by Sucrose Administration
Purpose. It has been demonstrated clearly that sucrose solutions given before a minor painful procedure can reduce pain among newborns.
- Trial name
- NCT05465694
- Testing
- 2-minute-time interval of per oral 24% sucrose, no time interval of per oral 24% sucrose
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Pain, Acute, Neonatal Intensive Care Unit
Non-pharmacological Methods in Pain Managment During Heel Stick in Preterm Infants
Aims and objectives: This study was performed to examine the effects of Non-nutritive sucking, breast milk odor, and Facilitated tucking on preterm infant pain before, during, and after heel-stick procedures.
- Trial name
- (pain) (NCT05281367)
- Testing
- Breast milk odor group, Facilitated tucking group, Non-nutritive sucking group
- Where
- Iran
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Negarin Akbari
Neonatal Disorder
Soft Tissue Therapy in Managing Procedural Pain Among Neonates.
Effect of Soft tissue Therapy in managing Procedural Pain among neonates admitted in neonatal intensive care unit. This study focuses on the Procedural pain management with the help of Soft tissue manipulation which includes…
- Trial name
- NCT04309162
- Testing
- Soft tissue therapy
- Where
- India
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Newborn, Neonatal Screening
Autonomic Nervous System Reactivity of the Newborn After a Nociceptive Stress: Interest of Sucrose and Non-nutritive Sucking
The management of the pain is a constant care concern in neonatal and maternity units. Many studies show an interest in the use of sugar solutions to reduce nociception during painful events in infants.
- Trial name
- BBSUCROSE (NCT02374281)
- Testing
- Glucose sucking, Water sucking, No sucking
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Neonatal Tongue-tie, Maternal Nipple Pain Upon Breastfeeding
Use of Topical Benzocaine for Analgesia in Lingual Frenotomy of the Newborn
Frenotomy of tongue-tie is commonly performed to resolve breastfeeding difficulties, eg maternal nipple pain and infant's latching difficulties. The procedure carries minor discomfort for the infants.
- Conditions
- Neonatal Tongue-tie, Maternal Nipple Pain Upon Breastfeeding, Neonatal Latch Difficulties
- Trial name
- NCT01274247
- Testing
- Topical Benzocaine
- Where
- Israel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center