Clinical trials: Neonatal Pain
Hypoxic-Ischemic Encephalopathy, Pain
Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)
Management of neonatal pain and sedation often includes opioid therapy. A growing body of evidence suggests long-term harm associated with neonatal opioid exposure.
- Trial name
- DICE (NCT04772222)
- Testing
- Dexmedetomidine Hydrochloride, Morphine Sulfate
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
Pain Management, Anxiety
Virtual Reality Distraction for Pain and Anxiety in Hemodialysis Patients
1. Assess pain and anxiety levels in hemodialysis patients during arteriovenous fistula needle insertion. 2. Determine the effect of the distraction technique using virtual reality on pain and anxiety levels during arteriovenous…
- Conditions
- Pain Management, Anxiety, Hemodialysis, Virtual Reality
- Trial name
- NCT07334522
- Testing
- Virtual Reality, standard of care
- Where
- 2 sites in Iraq
- Volunteers
- 142 people
- Sponsor
- Karbala University
Pes Planus
Exercises for Pes Planus
Pes planus is a musculoskeletal syndrome in which the medial longitudinal arch (MLA) of the foot is reduced or flattened. It results from a combination of static and dynamic abnormalities.
- Trial name
- NCT07123753
- Testing
- EXERCİSE
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Persistent Ductus Arteriosus, Complication of Prematurity
The Preterm Infants' Paracetamol Study
Present randomized, controlled, double-blind trial investigates the efficacy and safety of early (<24 h) intravenous paracetamol therapy for pain medication in very small premature infants.
- Conditions
- Persistent Ductus Arteriosus, Complication of Prematurity, Pain or Discomfort in Intensive Care of Preterm Infants
- Trial name
- PreParaS (NCT01938261)
- Testing
- paracetamol, 0.45 % saline solution
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- University of Oulu
Hemophilia
Myofascial Therapy in Patients With Hemophilic Arthropathy
Designing a treatment protocol using myofascial therapy for the treatment of pain and restrictions on mobility in patients with hemophilic arthropathy of the knee and ankle.
- Trial name
- He-Fascial (NCT02433782)
- Testing
- Myofascial therapy
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Hemodialysis, Arteriovenous Fistula Cannulation
Music-Assisted Acupressure for Pain During AVF Cannulation in Hemodialysis Patients
This randomized controlled trial was conducted to evaluate the effect of music-assisted acupressure on pain experienced during arteriovenous fistula (AVF) cannulation in hemodialysis patients.
- Conditions
- Hemodialysis, Arteriovenous Fistula Cannulation, Procedural Pain
- Trial name
- MUSIC-ACUP (NCT07657923)
- Testing
- Music Therapy, Acupressure, Music-Assisted Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Gülsüm Gülşen
Pain, Analgesia
Non-Pharmacologic Interventions to Relief Pain in Healthy Newborns Submitted to Vaccination to Hepatitis B
Acute procedural pain in neonates may be alleviated by non-pharmacological procedures. This study objective is to test the efficacy regarding pain attenuation of 3 interventions (skin-to-skin contact versus glucose 25% versus…
- Trial name
- NCT00713986
- Testing
- Water 2mL PO 2 minutes prior to intra-muscular injection, skin-to-skin contact, Glucose 25% 2 mL PO 2 minutes prior to injection
- Volunteers
- 640 people
- Sponsor
- Federal University of São Paulo
Ankyloglossia, Oral Mucoceles
The Effect of Pre-emptive Analgesia on the Postoperative Pain in Children Undergoing Pediatric Stomatology Day Surgeries
The aim of this double-blinded, randomized, controlled trial was to test whether pre-emptive analgesia with ibuprofen suppository is effective for children undergoing pediatric stomatology day surgeries in the postoperative…
- Conditions
- Ankyloglossia, Oral Mucoceles, Supernumerary Teeth
- Trial name
- NCT05878262
- Testing
- ibuprofen suppository
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Thalassemia
Assessment of Pain in People With Thalassemia Who Are Treated With Regular Blood Transfusions
Thalassemia is an inherited blood disorder that can result in mild to severe anemia. Regular blood transfusions, which refresh the healthy red blood cell supply, are one treatment for thalassemia.
- Trial name
- NCT00872833
- Where
- 9 sites in United States, Canada
- Volunteers
- 32 people
- Sponsor
- Carelon Research
Heel Pain Syndrome
Two Methods of Analgesia for Chinese Term Infants Receiving Heel Lance
1. The purpose of this study is to research and compare two sucking modes' effect(breast-feeding and non-nutritive sucking) and difference,hypothesis is that these two kinds of methods can decrease pain for Chinese term infants…
- Trial name
- NCT01355640
- Testing
- breast-feeding, non-nutritive sucking
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Respiratory Disease of A Newborn
Swaddling and Facilitated Tucking During Nasal CPAP Application
This study was planned to determine the effects of fetal position and swaddling during nasal CPAP application on pain, stress level, comfort and physiological parameters of the newborn.
- Trial name
- NCT07077148
- Testing
- Facilitated tucking, Swaddling
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Recep Tayyip Erdogan University
Preterm Labor, Preterm Contractions
Screening To Obviate Preterm Birth
Our objective is to investigate the predictive value of a panel of biomarkers associated with two biologically plausible pathways of preterm birth: membrane breakdown and cervical remodeling.
- Conditions
- Preterm Labor, Preterm Contractions, Abdominal Cramping, Back Pain
- Trial name
- STOP (NCT01868308)
- Where
- United States
- Volunteers
- 589 people
- Sponsor
- University of Pennsylvania
Cervical Disc Disorders
Clinical Outcome After Anterior Cervical Decompression and Fusion and Cervical Total Disc Replacement
The aim of this study is to examine the clinical outcome after anterior cervical decompression and fusion, and cervical disc prostheses in general.
- Trial name
- NCT02498028
- Testing
- Cervical Fusion, Cervical disc Prostheses
- Where
- 2 sites in Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital, Bonn
Inguinal Hernia, Femoral Hernia
Factors Influencing the Results of Treatment in Patients With Hernias of Various Localizations
The study attempts to quantify the relative risks for acute postoperative pain, complications rate, chronic postoperative pain (CPIP) and recurrence rate after different methods of repair of groin, umbilical and incisional hernia…
- Conditions
- Inguinal Hernia, Femoral Hernia, Umbilical Hernia, Ventral Hernia
- Trial name
- NCT05920200
- Testing
- open non-mesh hernia repair, open mesh hernia repair, MIS hernia repair
- Where
- Russia
- Volunteers
- 4,000 people
- Sponsor
- Immanuel Kant Baltic Federal University
Pain
Oral Glucose Solution as Pain Relief in Newborns: Results of a Clinical Trial
This study investigates which concentration of glucose is most effective in reducing pain for venipuncture in the newborn.
- Trial name
- NCT00847028
- Testing
- glucose 10%, 20% glucose, glucose 30%
- Where
- Belgium
- Volunteers
- 304 people
- Sponsor
- Universiteit Antwerpen
Patellofemoral Pain Syndrome
Effects of Agility Training With and Without Foot Mobilization In Patellofemoral Pain Syndrome.
Patellofemoral pain syndrome (PFPS) is referred to as peripatellar or retro-patellar pain, which is characterized by alterations in the physical and biomechanical features of the patellofemoral joint.
- Trial name
- NCT06674707
- Testing
- Agility Training with Foot mobilization., Agility Training without Foot mobilization
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Pain, Stress
Study of Spirit Pass in Newborn and Patient
Stress is a multiple variable and an inevitable aspect of life. Any change that affects the life of a person is a stressful agent, being possible to widely vary its nature and may be formed by several components, since…
- Trial name
- SSPNP (NCT02489136)
- Testing
- laying of hands (Spiritist "passe")
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Sickle Cell Disease
A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease
Our long-term goal is to reduce stress and improve sickle cell disease (SCD) pain control with less opioid use through an intervention with self-management relaxation/distraction exercises (RDE), named You Cope, We Support…
- Trial name
- NCT04484272
- Testing
- Self-monitoring of pain, stress, and opioid use + alerts/reminders + use of YCWS. [three video banks of RDE + Support])., Self-monitoring of pain, stress, and opioid use + alerts/reminders.
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- University of Florida
Preterm Neonates, Heel Lance Procedures
Crochet Octopus in Reducing Procedural Pain During Heel Lance in Preterm Neonates
Neonates, particularly those hospitalized in neonatal intensive care units (NICUs), are subjected to numerous painful procedures essential for their diagnosis and monitoring.
- Conditions
- Preterm Neonates, Heel Lance Procedures, Procedural Pain
- Trial name
- RCT (NCT07828795)
- Testing
- Crochet Octopus
- Volunteers
- 98 people
- Sponsor
- Mansoura University