Clinical trials: Neonatal Resuscitation
Face Mask Ventilation in Neonatal Resuscitation
Applied Forces During Neonatal Ventilation With Different Face Masks
This trial compares the applied forces exerted on the face of a modified preterm neonatal manikin with three different face masks.
- Trial name
- NCT07161752
- Testing
- Anatomical face mask 1, Anatomical face mask 2, Round face mask
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Infant, Newborn
Risk Related Assistance During Stabilization In Newborns At Birth
Approximately 10% of term infants and up to 50% of preterm infants less than 32 weeks require stabilization and / or ventilatory support at the time of transition at birth.
- Trial name
- NCT05023694
- Testing
- Video recordings, Video recordings after corrective measures in adverse events
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Manuel Sanchez Luna
Infant, Premature, Diseases, Birth, Preterm
The NEU - CAP Trial
The aim of NEU-CAP is to investigate the clinical impact of using a colorimetric carbon dioxide (CO₂) detector during non-invasive ventilation (NIV). Infants born before 32 weeks of gestation will be included in this trial.
- Conditions
- Infant, Premature, Diseases, Birth, Preterm, Respiratory Distress Neonatal
- Trial name
- NEU-CAP (NCT07754032)
- Testing
- Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation
- Volunteers
- 1,860 people
- Sponsor
- Leiden University Medical Center
Manual Ventilation
Comparison of Two Different Resuscitation Devices
There is a complex physiological process involved in establishing regular breaths at birth. After initiation of the first breath, fluid is removed from the alveoli and enough pressure must be generated to inflate the lungs .
- Trial name
- NCT03587987
- Testing
- Neopff, rPap
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College Cork
Premature Birth
Order Effects of Prematurity Outcome Data
Women recruited from the internet were put in a hypothetical situation of being in labor at 22 weeks of pregnancy, and presented with information in the form of pictographs about survival and disability of babies born at this…
- Trial name
- NCT04269616
- Testing
- Order of pictographs provided to participants, Level of description in survival pictograph
- Where
- United States
- Volunteers
- 839 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Neonates Needing Resuscitation at Birth
Personal Protective Equipment for the Prevention of SARS-Cov-2 During Neonatal Resuscitation
There has been an increasing number of SARS-CoV-2 infections in pregnant women and neonates. Interventions including open airway suctioning, positive pressure ventilation, non-invasive respiratory support, tracheal intubation…
- Trial name
- NCT04666233
- Testing
- Neonatal resuscitation with PPE for the prevention of SARS-Cov-2 infection, Neonatal resuscitation without PPE for the prevention of SARS-Cov-2 infection
- Where
- 2 sites in Italy
- Volunteers
- 48 people
- Sponsor
- University Hospital Padova
Hypoxic-Ischemic Encephalopathy, Perinatal Asphyxia
Umbilical Cord Milking Versus Immediate Cord Clamping in Full Term Neonates (≥ 37 Weeks) Requiring Resuscitation
The objective of the study is to compare the incidence of Hypoxic ischemic encephalopathy (all stages) among singleton term neonates (≥ 37 weeks) requiring resuscitation who will undergo Umbilical cord milking as compared to…
- Trial name
- NCT06090968
- Testing
- Umbilical cord milking, Immediate cord clamping
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Lady Hardinge Medical College
Neonatal Resuscitation, Simulation-Based Education
Video-Based Self-Assessment in Neonatal Resuscitation Training
The aim of this study is to evaluate the effects of video-based self-assessment in simulation-based neonatal resuscitation skills training on neonatal resuscitation skills, clinical judgment, student satisfaction, and…
- Conditions
- Neonatal Resuscitation, Simulation-Based Education, Self-Assessment, Clinical Assessment
- Trial name
- NCT07867652
- Testing
- Video-Based Self-Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Asphyxia Neonatorum
Intraosseous Infusion for Neonatal Asphyxiated Resuscitation
Intraosseous infusion is better than umbilical vein infusion for neonatal asphyxiated resuscitation
- Trial name
- NCT01866358
- Testing
- Intraosseous infusion, Umbilical vein infusion
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Third Military Medical University
Neonatal Resuscitation
SUCTIONING AT BIRTH WITH BULB SYRINGE OR SUCTION CATHETER: A RANDOMIZED CONTROLLED TRIAL
This study is designed to compare two different methods of oropharyngeal suctioning (with bulb syringe or suction catheter) in newborn infants at birth.
- Trial name
- NEOSUC (NCT05472155)
- Testing
- Bulb syringe, Suction catheter
- Where
- Ethiopia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Computer Simulation, Neonatal Resuscitation
Computer Debriefing and Screen-based Simulation
Debriefing after simulation plays a crucial role in student learning and medical practice. This paper focuses on impact of computer debriefing technique on knowledge retention of midwives during screen-based simulation of…
- Trial name
- NCT03844009
- Testing
- Computer integrated debriefing
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ilumens
Extreme Prematurity - Less Than 28 Weeks
Study of Room Air Versus 60% Oxygen for Resuscitation of Premature Infants
The most appropriate initial oxygen concentration for the resuscitation of the extremely low birth weight infant has not been established using large well designed, randomized, blinded, prospective trials and the level of oxygen…
- Trial name
- PRESOX (NCT01773746)
- Testing
- Neonatal Resuscitation
- Where
- 22 sites in United States, Austria and 10 more
- Volunteers
- 80 people
- Sponsor
- Sharp HealthCare
Death, Neurodevelopmental Impairment
Apgar-Score in Asphyxiated Infants Under Resuscitation
The specified Apgar-Score in combination with the AAP-Score predicts the morbidity and mortality of asphyxiated newborns.
- Trial name
- NCT01193751
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technische Universität Dresden
Intraventricular Hemorrhage
Neonatal Resuscitation With Intact Cord
The purpose of this study is to examine whether providing ventilation during delayed umbilical cord clamping provides greater placental transfusion and improved hemodynamic transition at birth.
- Trial name
- NRIC (NCT02231411)
- Testing
- V-DCC, Delayed cord clamping, Dry and and if apneic initially can stimulate by gently rubbing the back for approximately 30 seconds with warm sterile towels
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Sharp HealthCare
Prematurity, Oxidative Pulmonary Injury
The Effect of Oxygen Exposure During Newborn Resuscitation on Lung Injury
Hypothesis: In this feasibility study, hyperoxemia, as approximated by transcutaneous hemoglobin saturation with oxygen (Sp02), at the time of birth will cause sustained pulmonary oxidative stress as demonstrated by elevation of…
- Trial name
- NCT00355875
- Testing
- titration of oxygen during resuscitation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Infant Showing No Response to Resuscitation, Ventilator Adverse Event
Identifying the Most Accurate Method for Predicting the Safe Depth of Orally Placed Neonatal Endotracheal Tubes (ETT).
Placing artificial airways in infants is often performed under emergent life-saving conditions, which necessitates a procedure that is both accurate and efficient.
- Conditions
- Infant Showing No Response to Resuscitation, Ventilator Adverse Event, Apparent Life Threatening Event in Newborn and Infant
- Trial name
- NCT02181894
- Where
- 5 sites in United States, Ireland
- Volunteers
- 8 people
- Sponsor
- University of Colorado, Denver
Asphyxia Neonatorum
Biomarkers And Neurological Outcome in Neonates (BANON)
Validation of biomarkers in a human population for their ability to diagnose the severity of neonatal asphyxia. These biomarkers linked to asphyxia have been identified in animal studies and a preliminary human study.
- Trial name
- NCT03357250
- Where
- 11 sites in Germany
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- Life Science Inkubator
Hypothermia, Newborn
Evaluation of Use of Plastic Bags to Prevent Neonatal Hypothermia-Part V
The overall hypothesis is that plastic bags used in combination with WHO thermoregulation care will reduce the incidence of hypothermia in preterm/low birth weight and full term infants when compared to routine WHO…
- Trial name
- NCT01604460
- Testing
- Resuscitation with torso plastic bag, Resuscitation-no plastic bag
- Where
- Zambia
- Volunteers
- 275 people
- Sponsor
- University of Alabama at Birmingham
Congenital Diaphragmatic Hernia
Resuscitation of Infants With Congenital Diaphragmatic Hernia With an Intact Umbilical Cord
Congenital diaphragmatic hernia (CDH) is a severe birth defect, with a prevalence of 1:2000 to 1:3000 live births where a defect in the diaphragm results in, herniation of the abdominal contents into the chest with subsequent…
- Trial name
- NCT03242044
- Testing
- Congenital diaphragmatic hernia resuscitation with an intact umbilical cord
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Electronic Fetal Monitoring, Fetal Hypoxia
Oxygen for Intrauterine Resuscitation of Category II Fetal Heart Tracings
Maternal oxygen administration for concerning fetal heart rate tracing (FHT) patterns is common practice on Labor and Delivery units in the United States.
- Conditions
- Electronic Fetal Monitoring, Fetal Hypoxia, Fetal-Placental Circulation
- Trial name
- O2C2 (NCT02741284)
- Testing
- Room air, 10L Oxygen by nonrebreather mask
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine