Clinical trials: Neonatal Surgery
Dentofacial Deformity
Orthognathic Surgery and Postoperative Antibiotic Use
Currently there is debate in the literature as to the recommended length of postoperative antibiotics in patients undergoing orthognathic surgery.
- Trial name
- NCT01823523
- Testing
- Cefazolin, Cephalexin, Clindamycin
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Atlantic Center for Oral and Maxillofacial Surgery
Coagulopathy, Congenital Heart Disease
FFP Usage in Pediatric CV Surgery
When small children undergo heart surgery with the heart-lung machine, in the past, blood products to help the blood clot such as Fresh Frozen Plasma (FFP) was routinely used in children under 10kg.
- Trial name
- NCT05819788
- Where
- Canada
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Developmental Dysplasia of the Hip
Surgical Treatment of DDH With and Without Capsulorrhaphy
The goal of this interventional study is to evaluates the surgical treatment outcomes of Developmental Dysplasia of Hip with and without capsulorrhaphy between 1-6 years of age .
- Trial name
- NCT06442722
- Testing
- DDH with capsulorrhaphy, DDH without capsulorrhaphy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Emesis, Postoperative, Maxillofacial Abnormalities
Effects of Antiemetic Agents in Orthognathic Surgery Patients
In an effort to prevent or treat consistently high rates of PONV following maxillofacial operations, several medications, techniques and multimodal protocols have been studied.
- Trial name
- NCT06454825
- Testing
- Intravenous drug
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Acute Kidney Injury, Congenital Heart Disease
Acute Kidney Injury After Cardiac Surgery on CPB
The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne…
- Conditions
- Acute Kidney Injury, Congenital Heart Disease, Surgery, CBP
- Trial name
- NCT03513718
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Hypospadias
Analgesia in Pediatric Hypospadias Surgeries
The primary aim of the current study will be to use the duration until the first postoperative analgesic requirement after two different block techniques to compare the analgesic effect.
- Trial name
- NCT06410482
- Testing
- US guided caudal block, Dorsal penile nerve block
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Distress, Emotional
Mother Scented Simulated Hand for Mechanically Ventilated Preterm Neonates During Invasive Procedures?
This study aimed to determine the effect of Mother-Scented Simulated Hand (MSSH) on promoting comfort among mechanically ventilated preterm neonates during invasive procedures.
- Trial name
- Zaky-Hand (NCT05080582)
- Testing
- Mother-Scented Simulated Hand, NICU Standard Care
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Subtalar Arthrorisis, Flat Feet
Arthrorisis of the Subtalar Joint With a Polymeric Endorthesis for Flexible Flatfoot Treatment During the Growth Age Prospective Evaluation
Arthrorisis of the subastragalus joint represents one of the surgical treatments for addressing flexible flatfoot, a condition caused by joint deformity.
- Conditions
- Subtalar Arthrorisis, Flat Feet, Growth Age
- Trial name
- NCT06091371
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Cleft Palate Children
Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery
Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood.
- Trial name
- NCT07279883
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Right Ventricle, Pulmonary Valve Stenosis
Follow Up on Freestyle Valves in Children
The purpose of this study is to determine if the Medtronic Freestyle porcine valve is effective over a long period of time when it is used to replace the valve that normally allows blood to flow from the right lower pumping…
- Conditions
- Right Ventricle, Pulmonary Valve Stenosis, Pulmonary Valve Atresia
- Trial name
- NCT00385112
- Testing
- Echocardiogram
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Emory University
Preterm
The Effect of Surgical Incision Drep Use in Endotracheal Tube Fixation
It is aimed to minimise both unplanned extubation and skin damage with the surgical incision drep that we will use to fix the endotracheal tube in neonatal preterm infants and to reduce the complications that may develop due to…
- Trial name
- NCT06832553
- Testing
- surgical incision drep
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Umbilical Cord Blood, Cesarean Section Surgery
Effect of Delivery Time on Umbilical Cord Blood Gas Parameters in Cesarean Sections Under General and Spinal Anesthesia
The goal of this observational study is to evaluate the effect of neonatal delivery time on umbilical cord blood gas parameters in pregnant women undergoing elective cesarean section under general or spinal anesthesia.
- Conditions
- Umbilical Cord Blood, Cesarean Section Surgery, General Anesthesia, Spinal Anesthesia
- Trial name
- DELTA-CS (NCT07321041)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Myelomeningocele
In Utero Surgery for Fetal Myelomeningocele: Decision-making Mechanisms and Psychological Impact of Prenatal Therapy
Myelomeningocele is a malformation of the spine and spinal cord, generally diagnosed prenatally, and responsible for a complex disability for the unborn child.
- Trial name
- PriumPsy (NCT06796972)
- Testing
- Semi-structured interviews with a psychologist
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fuchs Dystrophy, Cataract
The Evaluation of Balanced Salt Solution During Cataract Surgery
This study aims to identify if the use of BSS PLUS® Sterile Intraocular Irrigating Solution as an irrigation solution leads to improved corneal outcomes vs BSS® Sterile Irrigating Solution in more compromised corneas.
- Trial name
- NCT05853978
- Testing
- BSS Plus, BSS
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Adam Fedyk, MD, FACS
Retinal Diseases, Fuchs Endothelial Dystrophy
DISCOVER Study: Microscope-integrated Intraoperative OCT Study
Optical coherence tomography (OCT )provides high resolution information regarding the anatomic structure of the tissues of the eye in a cross-sectional and 3 dimensional view.
- Conditions
- Retinal Diseases, Fuchs Endothelial Dystrophy, Macular Hole, Epiretinal Membrane
- Trial name
- DISCOVER (NCT02423213)
- Where
- United States
- Volunteers
- 2,911 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Mandibular Hypoplasia
Applicability Clinic of Cement Portland Structural White in Endodontic Surgery
Thirty teeth twelve patients, two female and a male, who had persistent periradicular lesions were selected to participate in this study.
- Trial name
- NCT02474615
- Testing
- ENDODONTIC SURGERY
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Bladder Exstrophy
Pelvic Osteotomy in Bladder Exstrophy
The study focuses on the surgical treatment of bladder exstrophy, a congenital condition where the bladder is located outside the body.
- Trial name
- NCT06717386
- Testing
- diagonal pelvic osteotomy
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sohag University
OSA, Malocclusion
Changes of the Upper Airway Volume After Orthognathic Surgery
The aim of the present project is to analyze the impact from orthognathic surgery on the upper airway respiratory volume. The primary objective is comparison of differences in the in the airway changes due to maxillary movements…
- Conditions
- OSA, Malocclusion, Dentofacial Deformities
- Trial name
- NCT05060133
- Testing
- Orthognathic Surgery
- Where
- Sweden
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Lund University Hospital
Stable Angina Pectoris, Periodontitis
Effect of Periodontal Therapy on Asprosin in Stable Angina
This study aims to evaluate the effect of non-surgical periodontal therapy on serum asprosin levels in patients with stable angina and periodontitis.
- Trial name
- NCT07591844
- Testing
- Non-surgical periodontal therapy (scaling and root planing), Non-surgical periodontal therapy (Professional dental cleaning)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University