Clinical trials: Neonatal Surgery
Mandibular Hypoplasia
Comparing Stability and Cost-Effectiveness of 3 Bicortical Screws Vs Adjustable Plate and 2 Bicortical Screws in Fixation of BSSRO
In this current study a comparison between 3 positional screws versus the adjustable plating system in conjunction with 2 positional screws. The patients will be selected to have retrognathic mandible requiring advancement.
- Trial name
- NCT02950727
- Testing
- 3 bicortical screws, adjustable plate and 2 bicortical screws
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Joseph Van Sickels
Obesity, Morbid
Laparoscopic Sleeve Gastrectomy-Induced Decline in Plasma Asprosin and Its Association With Metabolic Recovery
the present study aimed to systematically assess the changes in plasma asprosin levels at 3, 6, and 12 months after LSG, to explore the relationships between asprosin dynamics and key metabolic parameters, including body mass…
- Trial name
- NCT07008274
- Testing
- surgery
- Where
- China
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Dentofacial Deformities, Dentofacial Anomalies [Including Malocclusion] and Other Disorders of Jaw (M26-M27)
Effect of Proximal Segment Positioning on Postoperative Condylar Remodeling in Bimaxillary Orthognathic Surgery
Bimaxillary orthognathic surgery is a surgical procedure that involves simultaneous corrections to both the maxilla (upper jaw) and mandible (lower jaw).
- Trial name
- NCT06897787
- Testing
- manuel positioning group, mandibular basis osteotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Elective Penile Surgeries, Hypospadias
Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery
Caudal block is often performed to relieve postoperative pain in pediatric urological surgery. Recently, pudendal block is also used in penile surgery and it has advantage because of less side effects such as transient weakness…
- Conditions
- Elective Penile Surgeries, Hypospadias, Urethral Fistula or Stricture After Hypospadias Repair, Penile Curvature
- Trial name
- NCT02848157
- Testing
- Dexmedetomidine, plain ropivacaine, Ropivacaine
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
ERAS, Pediatric ALL
Pediatric Enhanced Recovery After Cardiac Surgery
Identify our institution's current perioperative management strategies for pediatric cardiac surgery patients. Identify predictive factors for receiving perioperative care following P-ERACS strategies.
- Conditions
- ERAS, Pediatric ALL, Congenital Heart Disease
- Trial name
- PERCS (NCT05665712)
- Testing
- enhanced recovery
- Where
- Canada
- Volunteers
- 483 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Dentofacial Deformities
Stability of Two Designs of Patient Specific Osteosynthesis For Fixation of LeFort 1 Osteotomy in Orthognathic Surgery
A comparison of the stability of two different designs of patient specific fixation devices for the performance of splintless computer guided le fort 1 osteotomy in orthognathic surgery workflow for the correction of a variety of…
- Trial name
- NCT05522348
- Testing
- Stability of a two piece PSI deign in splintless maxillary orthognathic surgery, Stability of a one piece PSI deign in splintless maxillary orthognathic surgery
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Circumcision, Male
Gomco Versus Mogen: Which is Best? A Randomized Controlled Trial
The purpose of this study is to compare two commonly used circumcision clamps (Gomco and Mogen) to see which results in less neonatal pain.
- Trial name
- GMRT (NCT01726036)
- Testing
- Gomco Circumcision Clamp, Mogen Circumcision Clamp
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Hypospadia, Phimosis
Intelligence Changes Following Minor Surgery
Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted.
- Conditions
- Hypospadia, Phimosis, Inguinal Hernia
- Trial name
- NCT01483313
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- RenJi Hospital
Skin Laxity, Skin Tightening
Effects of QUANTUM Probe for Skin Rejuvenation and Subdermal Retraction in Patients Undergoing High-Definition Liposculpture
This prospective study aims to evaluate the safety and effectiveness of Quantum, a fully internal bipolar radiofrequency probe, for the treatment of prominent skin laxity, providing patients with a more toned and youthful…
- Conditions
- Skin Laxity, Skin Tightening, Body Contouring Surgery, Skin Elasticity
- Trial name
- Quantum001 (NCT06958978)
- Testing
- Quantum RF
- Where
- Colombia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Heart Defects, Congenital
NIRS Guidance Trail in Children's Heart Surgery
Heart surgery in young children involves some risks. This study looks at a new type of monitor that may reduce these risks. Near Infrared Reflectance Spectroscopy (NIRS) aims to measure if enough blood reaches vital organs in the…
- Trial name
- NIRS (NCT02157597)
- Testing
- NIRS based management, Control
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Diaphragmatic Hernia
Fetoscopic Tracheal Balloon Occlusion in Unborns With Severe Congenital Diaphragmatic Hernia - EUROTRIAL I
Diaphragmatic hernia detected in fetal life carries a high risk for postnatal demise due to lung underdevelopment. Clinical experience from prospective controlled non-randomized case series with fetoscopic tracheal balloon…
- Trial name
- NCT00373763
- Testing
- Fetoscopic tracheal balloon occlusion
- Where
- 2 sites in Germany
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Funnel Chest
Evaluation of Chest Wall Motility After MIRPE
Pectus excavatum (PE) is the most common congenital deformity of the chest wall and surgical treatment using the minimally invasive technique (MIRPE) is consolidating as the choice to perform PE correction.
- Trial name
- NCT05124626
- Testing
- MIRPE with two bars, MIRPE with one bar
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cleft Lip and/or Palate, Cleft Lip Bilateral
Conventional Versus Modified Pre-surgical Naso-Alveolar Molding Treatment in Cleft Lip and Palate Infants
The aim of this study is to evaluate and compare clinically conventional Pre-surgical Naso-Alveolar Molding (PNAM) treatment versus Modified Naso-Alveolar Molding protocol (MPNAM) in cleft lip and palate patients in terms of: 1.
- Trial name
- NCT06494098
- Testing
- Nasoalveolar Molding, Addition silicone impression
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
OSA, Malocclusion
Changes of the Upper Airway Volume After Orthognathic Surgery
The aim of the present project is to analyze the impact from orthognathic surgery on the upper airway respiratory volume. The primary objective is comparison of differences in the in the airway changes due to maxillary movements…
- Conditions
- OSA, Malocclusion, Dentofacial Deformities
- Trial name
- NCT05060133
- Testing
- Orthognathic Surgery
- Where
- Sweden
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Lund University Hospital
Hereditary Breast and Ovarian Cancer Syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis
Risk-Reducing Surgeries for Hereditary Ovarian Cancer
Based on studies of "Inherited Susceptible Genes Among Epithelial Ovarian Cancer" (NCT03015376, clinicaltrials.gov) and "Cohort Study of Universal Screening for Lynch Syndrome in Chinese Patients of Endometrial Cancer"…
- Conditions
- Hereditary Breast and Ovarian Cancer Syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Ovariectomy, Hysterectomy
- Trial name
- NCT03294343
- Testing
- salpingo-oophorectomy only by laparoscopy, salpingo-oophorectomy with hysterectomy by laparoscopy, Follow-up
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Lei Li
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Umbilical Hernia, Epigastric Hernia
Risk Factors for Poor Outcome After Epigastric and Umbilical Hernia Repair
Umbilical and epigastric hernia repairs are common and performed by numerous surgical techniques. Considering that the hernia repairs in general are relatively small and simple procedures there are disproportionate poor results.
- Trial name
- NCT01665859
- Where
- Denmark
- Volunteers
- 6,783 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Maxillofacial Abnormalities, Jaw Abnormalities
Digital Occlusal Wafer Versus Waferless Distal Segment Repositioning for BSSO in Skeletal Mandibular Deformities
Research studies continues to attempt testing modifications to refine the treatment protocols through computer assisted design or computer-generated surgical Wafer splints, have greatly revolutionized the incorporation of digital…
- Conditions
- Maxillofacial Abnormalities, Jaw Abnormalities, Prognathism, Retrognathia
- Trial name
- NCT05151042
- Testing
- wafer-less approach, Computer Guided orthognathic surgery using occlusal wafers
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Umbilical Cord Blood, Cesarean Section Surgery
Effect of Delivery Time on Umbilical Cord Blood Gas Parameters in Cesarean Sections Under General and Spinal Anesthesia
The goal of this observational study is to evaluate the effect of neonatal delivery time on umbilical cord blood gas parameters in pregnant women undergoing elective cesarean section under general or spinal anesthesia.
- Conditions
- Umbilical Cord Blood, Cesarean Section Surgery, General Anesthesia, Spinal Anesthesia
- Trial name
- DELTA-CS (NCT07321041)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Esophageal Atresia
Cardiorespiratory Performance and Pulmonary Microbiome in Patients After Repair of Esophageal Atresia
The majority of the clinical research on esophageal atresia focuses on the upper gastrointestinal tract. However, the trachea and the lung are also affected in many of these children, so that a lifelong pulmonary impairment may…
- Trial name
- NCT03767673
- Testing
- Initial Spirometry, Final Spirometry, Pulmonary microbiome (16S rDNA profiling)
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz