Clinical trials: Neonatal Surgery
Persistent Ductus Arteriosus
The Best Treatment Strategy: Surgical vs Pharmacological to Close the Ductus Arteriosus Persistent in Preterm Infants
The decision to treat patent ductus arteriosus in preterm infants, varies from a conservative, medical or immediate surgical treatment; although, at present, there is some controversy about this decision.
- Trial name
- NCT02602054
- Testing
- Surgical treatment, Control group
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Adenomatous Polyp, Crohn Disease
Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease
This study is being done to evaluate single incision laparoscopic surgery (SILS) for colorectal diseases, compared to multi-port laparoscopic surgery.
- Conditions
- Adenomatous Polyp, Crohn Disease, Familial Adenomatous Polyposis, Hereditary Intestinal Polyposis Syndrome
- Trial name
- NCT01656746
- Testing
- therapeutic laparoscopic surgery
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Congenital Heart Disease, Sepsis
Pro-Calcitonin Levels Following Pediatric Cardiac Surgery
First, we, the researchers, hope to find out the PCT response to heart surgery in children by taking blood before surgery and each day for four days after surgery.
- Conditions
- Congenital Heart Disease, Sepsis, Infection
- Trial name
- NCT00284570
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Emory University
Hypospadias, Postoperative Pain
Caudal Epidural Block and DPNB in Hypospadias
Hypospadias, seen in every 200-300 births, is one of the most common congenital anomalies of the penis and is defined as the urethral meatus being located in the ventral part of the penis instead of its normal place.
- Trial name
- NCT04215874
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Fuchs' Endothelial Dystrophy, Cataract
The Effects of Ripasudil in Patients With FED Undergoing Femtosecond Laser Assisted Cataract Surgery
The purpose of this research is to investigate the effects of ripasudil administered as an ophthalmic solution in patients with FED after femtosecond laser assisted cataract surgery.
- Trial name
- NCT06048380
- Testing
- Ripasudil
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore Eye Research Institute
Regional Anesthesia, Hypospadias
Ultrasound-guided PNB and DPNB for Pediatric Distal Hypospadias Surgery
Hypospadias repair is a urological surgical operation that is very painful in the postoperative period and requires long-term analgesia.
- Trial name
- NCT04668183
- Testing
- Pudendal nerve block group, Dorsal penile nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Women Who Had at Lease One Cesarean Section in the Past
Relation Between Complication in Repeated Cesarean Sections, Newborn Outcome and Surgical Characteristics and Maternal Information
To examine the relation between complication in Repeated Cesarean Sections and Newborn Outcome compared to number of repeated cesarean section and reasonf or surgery and personal medical information to the mother
- Trial name
- NCT02641574
- Testing
- compare complication
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Umbilical Hernia, Obesity
Abdominal Wall Block Study
Compare the ability of the transversus abdominis plane block (TAPB) and rectus sheath block (RSB) to provide surgical anesthesia for overweight and obese patients undergoing umbilical hernia surgery.
- Trial name
- TAPB (NCT03074240)
- Testing
- TAPB Group, RSB Group, conversion to general anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Florida
Congenital Heart Disease in Children
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
The proposed study will be a prospective, randomized, double blind, placebo controlled trial to compare the use of a continuous infusion versus intermittent ketorolac on postoperative patients in the pediatric cardiovascular ICU.
- Trial name
- CIVIK (NCT04040452)
- Testing
- Continuous ketorolac
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Phoenix Children's Hospital
Pectus Excavatum, Autonomic Dysfunction
Autonomic Dysfunction in Patients With Pectus Excavatum.
Investigators conducted a pilot study to to evaluate the autonomic function in participants with pectus excavatum before and after Nuss surgery.
- Conditions
- Pectus Excavatum, Autonomic Dysfunction, Surgery
- Trial name
- ADPE (NCT03346876)
- Testing
- Nuss surgery
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Premature Infant Sleep
Sleep Organization in Premature Infants With Feeding Difficulties
Babies born too soon, premature babies, can have complications following birth because their systems are immature. Hospitals help prevent deformities and delays in motor development by using therapeutic positioning to provide…
- Trial name
- NCT01946308
- Testing
- Conformational positioning system
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Hypotension, Neonatal Hypotension
Appropriate Dosage of Vasopressor in Neonates and Infants
In this study, the investigators will evaluate cerebral blood flow before and after drug infusion using ultrasound to suggest blood pressure criteria and dosage of ephedrine, a vasopressor, to maintain adequate cerebral blood…
- Conditions
- Hypotension, Neonatal Hypotension, Intraoperative Complications
- Trial name
- NCT06257316
- Testing
- EPHEDrine Hydrochloride 5 mg/ml
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Palate, Cleft
Evaluation of Quality of Life After Orthognathic Surgery in a Cleft Lip and Palate Context
The purpose of this study is to compare, prospectively, the quality of life of patients with cleft lip and palate before and after orthognathic surgery.
- Trial name
- ORTHOQOL (NCT04049058)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Lille
Anesthesia, Pain
Ketamine in Patients Undergoing Anterior Cervical Discectomy and Fusion
Ketamine is an IV anesthetic with non-opioid analgesic properties that has been shown to reduce pain while also decreasing intraoperative and postoperative opioid requirements when used in subanesthetic doses after a variety of…
- Conditions
- Anesthesia, Pain, Surgery
- Trial name
- NCT02378740
- Testing
- Saline, Ketamine
- Where
- United States
- Sponsor
- Northwestern University
Pregnancy, Infertility
Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis
The primary research hypothesis is that microsurgical varicocelectomy will result in an increase in live birth in infertile couples where the male partner has a palpable varicocele and an abnormal semen analysis in comparison to…
- Trial name
- VIA (NCT00767338)
- Testing
- Timed intercourse, Microsurgical varicocelectomy, Intrauterine insemination
- Where
- 9 sites in United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Hemophilia A
Study of Emicizumab Prophylaxis in Participants With Hemophilia A With or Without Inhibitors Undergoing Minor Surgical Procedures
This Phase IV, multicenter study will evaluate whether participants with Hemophilia A (PwHA) with or without inhibitors receiving emicizumab prophylaxis can safely undergo minor surgical procedures without additional prophylactic…
- Trial name
- NCT03361137
- Testing
- Emicizumab
- Where
- 8 sites in United States
- Volunteers
- 14 people
- Sponsor
- Genentech, Inc.
Craniosynostosis, Anesthesia
Influence of General Anesthesia on the Dynamic Changes in Brain Damage Markers During and After Craniosynostosis Operations in Infancy
The issue of anesthetics neurotoxicity is one of the most discussed topics in pediatric anesthesiology, thus it opens the question of the safety of commonly used anesthetics in the pediatric patient.
- Trial name
- TAnBrainDam (NCT05911139)
- Where
- Slovakia
- Volunteers
- 45 people
- Sponsor
- Comenius University
Malocclusion, Malocclusion in Children
Does the Generation to Which the Operator Belongs Influence the Orthodontic Miniscrew Insertion Accuracy in Dynamic Computer-guided Surgery?
The goal of this clinical trial is to access the miniscrew accuracy insertion via dynamic computer-guided systems, inserted by three different clinicians belonging to three different generations, in childern in late mixed…
- Conditions
- Malocclusion, Malocclusion in Children, Malocclusion; Displaced or Missing Teeth
- Trial name
- NCT06661551
- Testing
- Miniscrew insertion in dynamic-computer guided surgery
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Roma La Sapienza
Severe Sepsis, Organ Dysfunction Syndrome
Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients
The purpose of this study is to evaluate if enteral docosahexaenoic acid (DHA) administration attenuates the inflammatory cytokines and improve clinical outcomes in neonates who underwent cardiovascular surgery
- Trial name
- DHA-IRCO (NCT01049529)
- Testing
- Docosahexaenoic acid
- Where
- Mexico
- Volunteers
- 55 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Neonatal Surgery, Surgery--Complications
Neonatal Surgery Intensive Care Unit: Hacettepe Experience
Background: Surgical treatment in the neonatal period mostly consists of congenital anomalies. Due to the different characteristics of newborns, the practice of monitoring this group of patients by neonatal specialists in…
- Conditions
- Neonatal Surgery, Surgery--Complications, Newborn Morbidity
- Trial name
- NSICUHE (NCT04734002)
- Where
- Turkey (Türkiye)
- Volunteers
- 5,442 people
- Sponsor
- Hacettepe University