Clinical trials: Neoplasm, Breast
Stage IV Melanoma, Advanced Lung Cancer
Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer
The purpose of this study is to refine and pilot test educational material developed to educate and support patients receiving immunotherapy for advanced cancer.
- Conditions
- Stage IV Melanoma, Advanced Lung Cancer, Stage IV Non-Small Cell Lung Cancer, Unresectable Non-Small Cell Lung Carcinoma
- Trial name
- UPLIFT (NCT04670445)
- Testing
- Educational Video and QPL List, Usual Care
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Breast Cancer
Comparison of One-port and Two-port Tissue Expanders for Breast Reconstruction
Appropriate patients undergoing going immediate breast reconstruction with tissue expanders following mastectomy will be randomized to receive one-port or two-ports tissue expanders.
- Trial name
- NCT02725801
- Testing
- Allergen one-port tissue expander placement, AlloX2 two-port tissue expander placement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lesley Wong
Breast Cancer
Margin Optimisation Using Z-axis Assessment With Real-time Tomosynthesis (MOZART Study).
Breast-conserving surgery is commonly performed to remove early-stage breast cancer or ductal carcinoma in situ (DCIS). During surgery, the goal is to completely remove the tumour with a clear margin of normal tissue around it.
- Trial name
- MOZART (NCT07426809)
- Testing
- Standard 2D Specimen Mammography, Mozart 3D Specimen Radiography System
- Where
- Ireland
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Chemotherapy Effect
Skin Sensitivity Acupuncture and Kinesiotherapy on Breast Cancer Patients Subject to Chemotherapy With Taxans
Objective: to compare different therapies employing acupuncture needles, silicon pellets and kinesiotherapy in breast cancer patients to taxane chemotherapy cycles.
- Trial name
- Acupuncture (NCT03373032)
- Testing
- Stiper, Acupuncture, Exercise
- Where
- Brazil
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Breast Neoplasm, Primary Prevention
Project Breast47: Effect of an Educational Intervention
Breast cancer is the most frequently diagnosed malignant tumor in women. In 2018, in Spain, the estimated incidence was 101/100,000 women.
- Conditions
- Breast Neoplasm, Primary Prevention, Risk Factors, Telemedicine
- Trial name
- Breast47 (NCT05267171)
- Testing
- Web access
- Where
- Spain
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Electrochemically Sensing Prob, Breast Cancer Diagnosis
Electrochemical Biosensor Based on Lectin-functionalized Nitrogen, Sulfur-doped Graphene Quantum Dot Decorated Gold Nanoparticles for Breast Cancer Diagnosis: From Academic Research to Clinical Translation
In this research, considering benefits of the nitrogen, sulfur-doped graphene quantum dot (NSGQDs) and 3-dimensional gold nanoparticle (AuNP), we used these materials for the construction of a novel electrochemical biosensor to…
- Trial name
- NCT07034248
- Testing
- Electrochemical biosensor
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Bladder Carcinoma, Breast Carcinoma
The Vanguard Study: Testing a New Way to Screen for Cancer
The Vanguard Study is a feasibility study to explore several aspects of evaluating multi-cancer detection (MCD) tests in a future definitive randomized controlled trial.
- Conditions
- Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma, Esophageal Carcinoma
- Trial name
- NCT06995898
- Testing
- Biospecimen Collection, Device Usage, Electronic Health Record Review
- Where
- 46 sites in United States
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Breast-cancer
Seroma Formation After Modified Radical Mastectomy With Flap Fixation Technique in Breast Cancer Patients
The goal of this clinical trial is to evaluate the effectiveness of mastectomy flap fixation in breast cancer patients. The main questions it aims to answer are: To compare seroma formation after mastectomy flap fixation with…
- Trial name
- NCT06243796
- Testing
- Flap fixation technique
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nakhon Phanom Hospital
Health Literacy, Breast Cancer Awareness
A TEACH-BACK APPROACH TO INCREASE BREAST CANCER KNOWLEDGE IN WOMEN WITH LOW HEALTH LITERACY: AN INTERVENTION STUDY
Objective: This study aims to evaluate the effectiveness of the "Teach Back" technique in increasing breast cancer knowledge among women with limited health literacy.
- Trial name
- Teach-Back Met (NCT07777289)
- Testing
- Routine Health Education
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Buca Seyfi Demirsoy State Hospital
Healthy Volunteers, Breast Cancer, Metastatic
Harvest of CTCs From MBC Patients Using the Parsortix™ PC1 System
The purpose of this clinical study is to demonstrate that the Parsortix™ PC1 system enables the capture and harvest of circulating tumor cells (CTCs) from the peripheral blood of patients with metastatic breast cancer (MBC) and…
- Trial name
- HOMING (NCT03427450)
- Testing
- Blood draw
- Where
- 4 sites in United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- Angle plc
Breast Cancer, Ovarian Cancer
Genetic Risk Assessment for Cancer Education and Empowerment (GRACE) Project
GRACE is a randomized 3-arm trial to determine the comparative effectiveness of two remote cancer communication interventions: 1) a targeted generic print (TP) or 2) a tailored telephone-based counseling and navigation…
- Trial name
- GRACE (NCT03326713)
- Testing
- Telephone Counseling & Navigation (TCN), Mailed Targeted Print (TP), Usual Care (UC)
- Where
- United States
- Volunteers
- 668 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Hereditary Breast Carcinoma, Hereditary Malignant Neoplasm
Chatbot Utilization for Pedigree Creation and Cancer Risk Assessment in Cancer Genetic Counseling
This clinical trial studies whether a chatbot can be used to help collect medical history and perform cancer risk assessment among patients undergoing cancer genetic counseling.
- Trial name
- NCT07887620
- Testing
- Text Message -based Navigation Intervenion, Artificial Intelligence based Intervention
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Breast Cancer
Cancer Genetics CD-ROM for Hispanics
This project will build upon prior, successful research on the effectiveness of an interactive computer disk with readable only memory (CD-ROM) for educating women about breast cancer and genetic risk.
- Trial name
- NCT00525980
- Testing
- Computer Program, Focus Group, Written Materials
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Mammography Screening, Geriatrics
Breast Cancer Screening Decision Aid
This is a randomized survey study of 2 decision aids for breast cancer screening. Decision aids are tools that present structured information to patients about a medical test or treatment.
- Conditions
- Mammography Screening, Geriatrics, Decision Aid
- Trial name
- NCT07515846
- Testing
- Video based decision aid, Written decision aid
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yale University
Breast Cancer, Gynecologic Cancer
Mobile App Postoperative Home Monitoring After Enhanced Recovery Oncologic Surgery
This study will assess whether the implementation of a combination of ERAS (Enhanced Recovery After Surgery) protocols and postoperative followup via a smartphone app can offer 1) improved patient satisfaction, 2) virtual patient…
- Trial name
- ERAS-OncoRe (NCT03456167)
- Testing
- RecoverWell mobile app for follow-up care
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
Cancer, Cancer Metastatic
The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors
The purpose of this prospective, interventional, single-arm pilot study is to evaluate whether virtually delivered group-based physical activity is feasible for adolescent and young adult (AYA) cancer survivors.
- Conditions
- Cancer, Cancer Metastatic, Neoplasms, Breast Cancer
- Trial name
- NCT05131815
- Testing
- Virtual group based physical activity (BurnAlong) and Social Media Discussion Board
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Breast Cancer
A Trial of Itraconazole Effect on HRS-8080 Pharmacokinetics in Healthy Participants
This is a phase I study to evaluate the effect of Itraconazole on the pharmacokinetics of HRS-8080 in healthy participants and the safety of HRS-8080 administered alone and in combination with Itraconazole in healthy participants.
- Trial name
- NCT07229560
- Testing
- HRS-8080 Tablet, Itraconazole Capsule
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Breast Cancer
Patient Controlled Tissue Expansion for Breast Reconstruction
This study is designed to compare the performance and safety of the AirXpander tissue expander to standard saline expanders in patients undergoing two-stage breast reconstruction following mastectomy.
- Trial name
- XPAND (NCT01425268)
- Testing
- AeroForm Tissue Expansion, Saline Tissue Expansion
- Where
- 17 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- AirXpanders, Inc.
Breast Cancer
Modified Pectoral Nerve Block Versus Serratus Plane Block
In PECSII or modified PECSI block, local anesthetic (LA) is injected between pectoralis major muscle (PMm) and pectoralis minor muscle (Pmm) to block lateral and medial pectoral nerves and between pectoralis minor muscle (Pmm)…
- Trial name
- NCT04895397
- Testing
- ultrasound guided Nerve Block procedure
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cancer Risk, Breast Cancer Risk
Development of New Methodologies and Innovative Tools for the diagnoSi and Therapeutic Treatment of uMAni Epithelial Tumors
The main objective of the SISTEMA project is to develop non-invasive diagnostic tests for the detection and quantification in blood of markers of Mesenchymal Epithelial Transition, a mechanism that characterises certain types of…
- Conditions
- Cancer Risk, Breast Cancer Risk, Lung Cancer (NSCLC)
- Trial name
- SISTEMA (NCT06939049)
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- ASL Lecce
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