Clinical trials: Neoplasm
Oral Leukoplakia
Evaluation of Effect of Topical Melatonin in Treatment of Oral Leukoplakia
Oral leukoplakia is the most commonly occurring oral premalignant disorder. It has an overall prevalence rate of 1-4% with highest prevalence rate of 10.54% in Asian countries.
- Trial name
- NCT04251845
- Testing
- topical melatonin
- Where
- India
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Basal Cell Carcinoma
Vismodegib for Treatment of Basal Cell Carcinoma
The primary objectives of this study are to assess, using Mohs micrographic surgery (MMS) at the end of treatment, the efficacy (primary) and safety (secondary) of vismodegib compared to placebo in the oral adjunctive pre…
- Trial name
- Erivedge (NCT01543581)
- Testing
- Vismodegib
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Abel Torres, MD
Nerve Compression
Comparative Effects of Nerve Gliding Exercises and Conventional Grip Strength Exercises in Batters.
Cricket is transformed over the years and dynamic of batting has changed. Gone are the days, when batters used to play the game with defensive mindset.
- Trial name
- NCT06688266
- Testing
- Nerve Gliding Exercises, Hand Grip Strength Exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sehat Medical Complex
Cervical Carcinoma
A Community Based Intervention to Improve Cervical Cancer Screening Among Women in the Hispanic and East African Immigrant Community
This clinical trial studies whether a community based intervention improves cervical cancer screening (CCS) among women in the Hispanic and East African immigrant community.
- Trial name
- NCT07890402
- Testing
- HPV Self-Collection, Informational Intervention, Interview
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lynch Syndrome, Endometrial Cancer
Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome
Given that there is a significant prevalence of Lynch syndrome among patients with endometrial cancer (about 5% of patients with endometrial cancer), and given there is a known risk of endometrial cancer among patients with…
- Conditions
- Lynch Syndrome, Endometrial Cancer, Endometrial Hyperplasia, Mismatch Repair Deficiency
- Trial name
- NCT05257057
- Testing
- Immunohistochemical staining
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Colon Cancer Screening
Colonoscopy Bowel Prep Comparison Among Diabetic Patients
The goal of this clinical trial is to learn if the Golytely or SUPREP bowel preparation works more effectively in bowel cleansing for colorectal cancer screening with colonoscopy in patients with diabetes.
- Trial name
- NCT07351019
- Testing
- Golytely, SUPRPEP
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eisenhower Army Medical Center
Myasthenia Gravis, Neuromuscular Disease
Validation and Scaling of Screening Program for Undiagnosed Myasthenia Gravis-Social Media Campaign Paired With a Self-moderated Assessment
This study expands and validates the pilot study NCT06381284. It is a fully remote, site-less, prospective, observational study enrolling adults in the United States (excluding U.S.
- Conditions
- Myasthenia Gravis, Neuromuscular Disease, Neuromuscular Manifestations
- Trial name
- NCT06866483
- Testing
- Social media recruitment, Self-Assessment, Follow-up
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ZS Associates
Alopecia, Breast Cancer
Bimatoprost Ophthalmic Solution in Increasing Eyebrow and Eyelash Growth in Patients Who Have Undergone Chemotherapy for Breast Cancer and in Healthy Participants
RATIONALE: Bimatoprost ophthalmic solution may help increase eyebrow and eyelash growth in patients who have undergone chemotherapy.
- Trial name
- NCT00999557
- Testing
- bimatoprost ophthalmic solution
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Hematologic Malignancy
Home Transfusion for HEME
The purpose of the research is to assess the feasibility and acceptability of a home blood transfusion program for patients with hematologic malignancies who need blood transfusions
- Trial name
- NCT05509439
- Testing
- Home Transfusion Program Components
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Port a Cath
Structured Training on Oncology Nurses' Performance Related Port A Cath Device
evaluate the effect of structured simulation-based training on oncology nurses' performance regarding port A cath device.
- Trial name
- NCT05774301
- Testing
- simulation-based training
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Breast Cancer Awareness
The Effect of a Hybrid Approach in Breast Cancer Education on Women's Awareness, Fatalism, and Self-Compassion Levels: A Randomized Controlled Trial
This randomized controlled trial aims to evaluate the effect of a hybrid breast cancer education program on women's breast cancer awareness, cancer fatalism, and self-compassion levels.
- Trial name
- NCT07828119
- Testing
- Hybrid Breast Cancer Education
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Breast Cancer
Vibro-Acoustography Imaging in Finding Breast Microcalcifications and Lesions in Women
RATIONALE: New diagnostic procedures, such as vibro-acoustography imaging, may be an effective method of finding microcalcifications and lesions in the breast.
- Trial name
- NCT00626119
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Barrett Esophagus, Gastroesophageal Reflux
Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
The goal of this clinical trial is to develop a method to detect Barrett's esophagus in individuals with a new office based diagnostic test.
- Conditions
- Barrett Esophagus, Gastroesophageal Reflux, Esophageal Adenocarcinoma
- Trial name
- NCT06687603
- Testing
- EsoCheck, EsoGuard
- Where
- 5 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Cancer, Non-Hematologic Malignancy
Metabolic and Immunological Phenotyping in Patients With Cancer
An observational study to investigate cachexia in participants with non-haematological cancer.
- Trial name
- MIPPaC (NCT04285242)
- Testing
- Observational assessments
- Where
- 2 sites in United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- CCTU- Cancer Theme
Predisposition, Genetic, Cancer
Investigating the Role of Genetics in Disease Predisposition
Gametogenesis is the production of sperm and eggs; it takes place through the process of meiosis. Gametogenesis is subject to the acquisition of mutations as with other processes in the body.
- Conditions
- Predisposition, Genetic, Cancer, Mutation, Fertility Disorders
- Trial name
- NCT06584994
- Testing
- sample collection
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Wellcome Sanger Institute
Ovarian Cancer
Innovative Ovarian Cancer Biomarker Assays
Ovarian cancer is often diagnosed at a later stage because early symptoms can be mild or non-specific. Earlier detection of ovarian cancer could improve treatment options and outcomes.
- Trial name
- DISARM CSB (NCT07693894)
- Testing
- Investigational ovarian cancer biomarker assays
- Where
- 7 sites in Czechia, Greece and 3 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Breast Cancer
Molecular Breast Imaging in Screening Breast Cancer
The molecular breast imaging (MBI) is a potential modality to screen breast cancer. In this study, we compare and evaluate the recall rate/diagnostic efficiency of MBI, mammography and breast sonography, and aim to determine best…
- Trial name
- NCT03082456
- Testing
- Molecular breast imaging, Mammography, Breast ultrasound
- Where
- Taiwan
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Dementia, Mild
Trial-based Effectiveness and Cost-effectiveness of the Partner in Balance Intervention
Rationale: Informal care is one of the most important sources of care for dependent elderly people. The Partner in Balance (PIB) intervention aims to prepare and support informal caregivers for their caregiving tasks.
- Trial name
- NCT05450146
- Testing
- Partner in Balance
- Where
- Netherlands
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Cognitive Impairment
Health Care Courses of Elderly Hospitalized Patients for Inappropriate Reasons: Qualitative and Economic Analyzes
For almost 17 % of cases patients over 75 years are sent for inappropriate reasons to the emergency unit. They are described as inappropriate hospitalization because they don't require the use of technical platform or diagnostic…
- Trial name
- PAGE (NCT02749669)
- Testing
- Qualitative research
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Régis AUBRY
Hepatic Impairment
A Phase I Study to Investigate the Effect of Hepatic Impairment on the PK, Safety, and Tolerability of AZD2693
Subcutaneous administration of AZD2693 single dose in participants with hepatic impairment
- Trial name
- NCT05919069
- Testing
- AZD2693
- Where
- 3 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
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