Clinical trials: Neoplasms, Prostate
Prostate Cancer
Mild Cognitive Impairment in Men Following Androgen Deprivation
MCI with ageing is thought in part to be related to reduced serum sex hormones which is well-recognised, especially in females, but poorly understood.
- Trial name
- NCT01691976
- Testing
- Oestrogen Patches, LHRHa
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Prostate Cancer
Daily Target Guided Radiation Therapy Using the Calypso 4D Localization System in Patients Who Have Had a Prostatectomy for Prostate Cancer
This study will evaluate the daily use of a unique daily organ tracking system on target localization in patients treated with radiation therapy after radical prostatectomy for prostate cancer.
- Trial name
- NCT01624623
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research Acquisition Activity
Prostate Cancer
The i4i PRODICT® Study: Evaluation of the i4i PRODICT® Test in Different Ethnic Groups (The i4i PRODICT® Study).
The i4i PRODICT® study has been developed to investigate the uptake and acceptability of the i4i PRODICT® test which combines both common and rare genetic changes (genetic variants) into one saliva-based DNA test to estimate a…
- Trial name
- NCT06636526
- Testing
- The i4i PRODICT® test., Prostate cancer screening, MRI Scan
- Where
- 3 sites in United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Institute of Cancer Research, United Kingdom
Anxiety, Prostate Cancer
proState Cancer Health Education to pRomote Early sreENing Uptake (SCREEN): A Pilot Randomised Control Trial
Prostate cancer is an issue of significant public health concern. Yet in low- and middle-income countries like Nigeria, men are adversely affected due to factors including poor early prostate cancer screening uptake.
- Conditions
- Anxiety, Prostate Cancer, Health Education, Screening and Brief Interventions
- Trial name
- SCREEN (NCT07800390)
- Testing
- proState Cancer awareness education to pRomote Early screENing uptake, Control group
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Teesside University
Prostatic Cancer, Surgery
Prothrombotic Factors and Anaesthesia in Prostate Cancer
This study aims to assess if different anesthetic techniques can affect coagulant factors in patients with prostate cancer undergoing elective laparoscopic radical prostatectomy (LRP).
- Trial name
- NCT01998685
- Testing
- Propofol, remifentanyl, Midazolam
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Prostate Cancer
External Immobilization Compared to Limited Immobilization Using a Novel Real-time Localization System of the Prostate
This prospective study at MAMC evaluates the utility of a rigid pelvic external immobilization compared to limited immobilization using a novel real-time localization system of the prostate.
- Trial name
- NCT01588938
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research Acquisition Activity
Prostate Cancer
Evaluating the Role of Ultrasound in Prostate Cancer
Active surveillance (AS) is becoming an increasingly common treatment option for men who have been diagnosed with localised low-grade prostate cancer (PCa).
- Trial name
- ERUP (NCT05326282)
- Testing
- Multi-parametric ultrasound
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Prostate Cancer (Adenocarcinoma), Radical Prostatectomy
Evaluation of Pelvic Floor Function and Psychosocial Sequelae Following Radical Prostatectomy for Prostate Cancer
This observational cross-sectional study aims to evaluate the effects of radical prostatectomy for prostate cancer on pelvic floor function and psychosocial well-being.
- Conditions
- Prostate Cancer (Adenocarcinoma), Radical Prostatectomy, Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- NCT07693647
- Testing
- No Interventions
- Where
- Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cancer
Role of Caregiver in the Clinical Pathway of Patients With Breast and Prostate Cancer
The following randomized longitudinal study will evaluate the long term impact of caregivers' involvement in cancer care pathway, including a psychological support intervention on the dyads to be delivered after the detection of…
- Trial name
- NCT06468293
- Testing
- Psychological support
- Where
- Italy
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
Prostate Cancer
Comparison of a Novel Leuprolide With Market Leuprolide
This is a single dose, randomized, single blind, parallel group study to evaluate the testosterone suppressive effect in healthy male volunteers of a novel leuprolide acetate 3.75mg depot vs market reference leuprolide acetate…
- Trial name
- NCT03662958
- Testing
- Lutrate, Enantone
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Prostate Cancer Stage, PSMA
99mTc-QULIC-5-P1 SPECT Imaging in Patients With Prostate Cancer
99mTc-QULIC-5-P1 is a new radiotracer targeting PSMA, which is promising as an excellent imaging agent applicable to PSMA positive prostate cancer.
- Conditions
- Prostate Cancer Stage, PSMA, SPECT
- Trial name
- NCT06419348
- Testing
- 99mTc-QULIC-5-P1
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Prostate Cancer
Music Listening as a Postanesthesia Care Unit (PACU) Nursing Intervention
A randomized comparison clinical trial will be conducted in laparoscopic radical prostatectomy patients in the Weinberg PACU at the Johns Hopkins Hospital.
- Trial name
- NCT04596917
- Testing
- Preferred music listening, Relaxation breathing narrative over hypnotic music listening
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Aromatherapy, Prostate Cancer
Aromatherapy on Pain and Anxiety of the Patients Undergoing Prostate Biopsy
The study included 120 male patients who would undergo a prostate biopsy. Patients were divided into 3 groups as placebo group (n = 40), Levander group (N = 40), and Frankincense group (n = 40).
- Conditions
- Aromatherapy, Prostate Cancer, Anxiety
- Trial name
- NCT06119438
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin Training and Research Hospital
Prostate Carcinoma
Urine Prostate Screening Integrated With MRI for Early Detection of Prostate Cancer, UPRISE Trial
This clinical trial tests how well a urine prostate cancer screening test, My Prostate Score 2 (MPS2), integrated with magnetic resonance imaging (MRI) works for early detection of prostate cancer.
- Trial name
- UPRISE (NCT07526545)
- Testing
- Biopsy Procedure, Diagnostic Procedure, Electronic Health Record Review
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Neoplasms, Prostate Cancer
Hispanic Adapted and Culturally Relevant Exercising Together
The purpose of this study is to determine the feasibility and effects of an adapted Exercising Together, a partnered resistance training program, on the physical and mental health of prostate cancer survivors and their informal…
- Conditions
- Neoplasms, Prostate Cancer, Exercise, Caregiver Burden
- Trial name
- HACER (NCT06018311)
- Testing
- Exercising together
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Prostate Cancer, Sexual Dysfunction
Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy
RATIONALE: Tadalafil may help prevent erectile dysfunction (ED) in patients with prostate cancer that has been treated with radiation therapy.
- Trial name
- NCT00931528
- Testing
- Tadalafil
- Where
- 192 sites in United States, Canada
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Radiation Therapy Oncology Group
Prostate Cancer, Prostate Nodule
A Prospective Pilot Study for the Evaluation of 18F- Fluciclovine PET/MRI in Radio-recurrent Prostate Cancer (RRPC-PET/MRI Study)
To perform both PET scans and MRIs in the same setting using a simultaneous PET/MRI scanner.
- Trial name
- NCT05035732
- Testing
- 18F-fluciclovine
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
PSMA-related Disease, Prostate Cancer
Prostate Specific Membrane Antigen PET/CT Imaging in PSMA-Related Disease Patients
To evaluate the potential usefulness of 68Ga/18F-PSMA/PSFA positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various PSMA-related disease patients (prostate cancer…
- Conditions
- PSMA-related Disease, Prostate Cancer, Positron Emission Tomography, Metastasis
- Trial name
- NCT06690970
- Testing
- 68Ga/18F-PSMA/PSFA
- Where
- 3 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Breast Cancer, Lung Cancer
Development of a Clinical Trial Specific Question Prompt List
The purpose of this study is to develop a Question Prompt List (QPL) about clinical trials for cancer patients and find out what cancer patients and their caregivers think of the QPL.
- Conditions
- Breast Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00662324
- Testing
- focus groups
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center