Clinical trials: Neoplasms, Prostate
Prostate Cancer
DeADT - Living Well With Prostate Cancer
The goal of this randomized de-implementation trial is to compare two strategies to reduce low-value androgen deprivation therapy (ADT) use for prostate cancer care.
- Trial name
- DeADT-LW (NCT06199986)
- Testing
- ADT Order Check Attestation (Or), Provider Script (Sc)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Prostate Cancer
The CArdiovascular Risk Evaluation in Men With Prostate Cancer Study (CARE-PC) Pilot Feasibility Study
The overarching goal of this trial is to develop mechanisms to improve cardiovascular care among such prostate cancer patients receiving ADT by increasing patient awareness of individualized cardiovascular risk estimates and…
- Trial name
- NCT06064149
- Testing
- CARE-PC Web-Based Application
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vivek Narayan
Prostate Cancer
Shared Decision Making: Prostate Cancer Screening
Interventions to Improve Shared Decision-Making: Prostate Cancer Screening is a prospective study of educational interventions to improve the interaction of physicians and their patients about prostate cancer screening.
- Trial name
- NCT00207649
- Testing
- Shared decision-making for PSA screening tool
- Where
- United States
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- Lisa Richarson
Prostate Cancer
Effects of a New Diagnostic Test on the Care of Prostate Cancer Patients: The ProMark™ Clinical Utility Study
The objectives of this study are to assess clinical practice variation in prostate cancer diagnosis and treatment among urologists and how ProMark™ affects clinical practice decision-making.
- Trial name
- NCT04550416
- Testing
- ProMark Information and Test Results
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Prostate Cancer, Colorectal Cancer
Reducing Cancer Disparities for American Indians in the Rural Intermountain West
The purpose of this demonstration is to evaluate the effectiveness of using community outreach workers (navigators) to help American Indians living in rural areas overcome barriers to appropriate cancer screening, diagnosis, and…
- Conditions
- Prostate Cancer, Colorectal Cancer, Breast Cancer, Cervical Cancer
- Trial name
- NCT00380055
- Testing
- Navigation Services, Cancer education
- Where
- 2 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University of Utah
Prostate Cancer
The Effect of Radiation on Semen Quality and Fertility in Men With Prostate Cancer
Many younger men are diagnosed with prostate cancer. These patients are often choosing radiation therapy as their primary treatment.
- Trial name
- NCT00496249
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Dissemination of Prostate Cancer Screening to PCP's in African American Communities
The aims of this project are to adapt and extend the use of academic detailing to the dissemination of prostate cancer (CaP) screening findings to primary care physicians practicing in African American communities.
- Trial name
- NCT00629330
- Testing
- Academic Detailing
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Columbia University
Breast Cancer, Colorectal Cancer
Detection of Cancer in Breath Samples by Trained Detection Dogs
The goal of this study is to show that trained detection dogs can identify breast, lung, prostate or colorectal cancer by sniffing masks containing breath samples.
- Conditions
- Breast Cancer, Colorectal Cancer, PROSTATE CANCER, Lung Cancer
- Trial name
- NCT06255041
- Where
- 2 sites in Israel
- Volunteers
- 1,386 people, healthy volunteers welcome
- Sponsor
- SpotitEarly
Adrenal Cortical Cancer, Brain Cancer
Spectroscopy With Surface Coils and Decoupling
The purpose of this study is to obtain chemical information from part of your body without a biopsy. This is done using a technique called magnetic resonance spectroscopy (MRS) which is similar to magnetic resonance imaging (MRI)…
- Conditions
- Adrenal Cortical Cancer, Brain Cancer, Breast Cancer, CNS Cancer
- Trial name
- NCT00581815
- Testing
- Proton-decoupled 31P MRS at 1.5T, 1H Spectroscopy at 1.5T and 3T
- Where
- United States
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
PD-L1-expressing Regulatory T Cells in Localized Prostate Cancer Patients Undergoing Iodine-125 Permanent Brachytherapy
Immunotherapy is currently revolutionizing the field in oncology. However, prostate cancer is poorly responsive to immune checkpoint inhibition.
- Trial name
- NCT04369508
- Testing
- permanent brachytherapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Prostate Cancer
the Beijing Randomized Study Of Prostate Cancer Screening
BROPCS is a randomized trial study comparing the effectiveness of traditional systematic biopsies and bpMRI followed targeted biopsies with PSA > 4ng/ml in initial screening.
- Trial name
- BROPCS (NCT05961514)
- Testing
- Target biopsies, systemic biopsies
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Prostate Cancer, Polygenic Risk Score
Polygenic Risk Stratification Combined With mpMRI to Identify Clinically Relevant Prostate Cancer
The goal of this clinical trial is to evaluate a screening method to detect clinically relevant prostate cancer. This clinical trial is using genetic data to determine a man's risk of cancer, together with multiparametric…
- Trial name
- PRS (NCT06398639)
- Testing
- Polygenic Risk Score (PRS)
- Where
- 5 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Adam S. Kibel, MD
Prostate Cancer
68Ga-NOTA-RM26 PET/CT in Prostate Cancer Patients
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-RM26 in prostate cancer patients.
- Trial name
- NCT03164837
- Testing
- 68Ga-NOTA-RM26
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Metastatic Castration-resistant Prostate Cancer
177Lu-EB-PSMA617 in Patients With Metastatic Castration-resistant Prostate Cancer
This is an open-label, non-controlled, non-randomized study to assess the safety and measure image-based absorbed dose of 177Lu-EB-PSMA-617 in patients with metastatic castration-resistant prostate cancer (mCRPC) who will undergo…
- Trial name
- NCT03403595
- Testing
- 177Lu-EB-PSMA-617
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Prostate Cancer, Genetic Predisposition to Disease
Prophylactic Prostatectomy for Prostate Cancer (PPPC)
Prostate cancer affects 1-in-8 people assigned male at birth in the UK and kills almost 12,000 annually. Half the cases occur due to genetic factors.
- Conditions
- Prostate Cancer, Genetic Predisposition to Disease, BRCA Mutation
- Trial name
- PPPC (NCT06470685)
- Testing
- Qualitative Research Interviews
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Prostate Cancer
Evaluation of an Online Prostate Cancer Screening Decision Aid
The goal of this clinical trial is to learn if the online, simulated human "Talk to Nathan About Prostate Cancer Screening" decision aid (https://www.cdc.gov/prostate-cancer/talk-to-nathan/index.html) is effective in helping…
- Trial name
- NCT06610474
- Testing
- Use of the online "Talk to Nathan about Prostate Cancer" decision aid, Use of a standard prostate cancer screening decision aid, Use of standard prostate cancer education materials
- Where
- 4 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- David Siegel
Cancer of Prostate
De-implementation of Low Value Castration for Men With Prostate Cancer
This study will use a theory-based, mixed methods approach to identify, tailor and pilot two different de-implementation strategies that vary widely in delivery, impact, and expected results for reducing low value androgen…
- Trial name
- DeADT (NCT03579680)
- Testing
- ADT ORDER CHECK ATTESTATION (OR), PROVIDER SCRIPT (SC)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Stage, Prostate Cancer
Sulforadex in Healthy Volunteers SAD
To determine the safety and tolerability of single escalating doses of Sulforadex® in healthy male volunteers.
- Trial name
- NCT01948362
- Testing
- Sulforadex, Alpha cyclodextrin
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Evgen Pharma
Prostate Cancer, Urine
Investigation of Urinary Biomarkers for the Detection of Prostate Cancer
The aim of this study is to investigate and possibly validate urinary biomarkers for prostate cancer. During this study the focus will be on aberrations of selected genes as prognostic or predictive value has been shown for these…
- Conditions
- Prostate Cancer, Urine, Liquid Biopsy
- Trial name
- URODETECT-WP2 (NCT05454371)
- Testing
- Colli-Pee UAS devices
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novosanis NV
Prostate Cancer
Artificial Intelligence (AI)-Assisted Risk-based Prostate Cancer Detection
This is a prospective clinical study recruiting 510 men at risk of PCa to undergo urine, blood, AI-assisted ultrasound and AI-assisted MRI investigations to stratify risk of clinically significant PCa (csPCa).
- Trial name
- NCT05443412
- Testing
- Diagnostic test for prostate cancer
- Where
- Hong Kong
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong