Clinical trials: Neoplasms, Solid Tumor
Solid Tumor, Solid Tumor, Adult
Psychotherapy Intervention for Latinos With Advanced Cancer
The purpose of this study is to adapt a counseling intervention called Meaning Centered Psychotherapy to make it culturally relevant for Latinos. Cancer affects patients and their loved ones.
- Conditions
- Solid Tumor, Solid Tumor, Adult, Solid Tumor, Unspecified, Adult
- Trial name
- NCT04015609
- Testing
- Meaning Centered Psychotherapy for Latinos, Functional Assessment of Cancer Therapy - Spiritual Well-Being Scale, Meaning Centered Psychotherapy for Latinos for Waitlist Control Patients
- Where
- 4 sites in United States, Puerto Rico
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
Stress Echocardiography to Identify Chemotherapy Induced Cardiotoxicity in Cancer Patients With Heart Failure Risk
This clinical trial evaluates changes in cardiac (heart) function during stress echocardiography to screen for chemically induced cardiotoxicity in cancer patients at a high risk for developing heart failure.
- Trial name
- NCT05950399
- Testing
- Echocardiography, Electronic Health Record Review, Questionnaire Administration
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Solid Tumor, Ovarian Cancer
Effect of PARP Inhibitors on Glomerular Filtration Rate
The purpose of this study is to observe whether PARP inhibitors have an effect on serum creatinine level, and whether this reflects a change in creatinine secretion or a true change in kidney function.
- Conditions
- Solid Tumor, Ovarian Cancer, Breast Cancer
- Trial name
- NCT04367467
- Testing
- Kidney Function Test
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Malignant Solid Neoplasm
Testing an Educational Program to Improve Goals of Care Conversations Between Patients and Their Care Teams
This clinical trial evaluates an educational program called Algorithm-Enabled Patients Activated in Cancer Care Through Teams (A-PACT) for reducing unplanned hospital visits and improving goals of care conversations with…
- Trial name
- NCT07278739
- Testing
- Best Practice, Educational Intervention, Electronic Health Record Review
- Where
- 7 sites in United States
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- SWOG Cancer Research Network
Solid Tumors
To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects
A study to assess the pharmacokinetics, safety and tolerability of Selumetinib (AZD6244, ARRY-142886) in patients with hepatic impairment and healthy subjects.
- Trial name
- NCT02063230
- Testing
- Selumetinib 50mg, Selumetinib 25mg
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
H1N1 Influenza Virus, Invasive Solid Tumors
Clinical Trial to Compare the Immunogenicity, Safety, and Tolerability of an Adjuvanted A(H1N1) Influenza Vaccine Versus Non-Adjuvanted A(H1N1) Influenza Vaccines in Patients With Invasive Solid Tumors
This is a phase III, randomized, controlled, open label study with two vaccine regimens. The study will assess the relative safety and immunogenicity of vaccine regimens comparing adjuvanted versus non-adjuvanted formulations of…
- Trial name
- NCT01031719
- Testing
- adjuvanted A(H1N1) influenza vaccine, non-adjuvanted A(H1N1) influenza vaccine
- Where
- 3 sites in Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Chiltern Pesquisa Clinica Ltda
COVID-19 Infection, Malignant Solid Neoplasm
Impact of the COVID-19 Pandemic and HRQOL in Cancer Patients and Survivors
This study uses questionnaires to gain an understanding of how experiences during the COVID-19 pandemic, regardless of COVID-19 status, may have impacted health-related quality of life (HRQOL) and other areas such as…
- Trial name
- NCT04447222
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Survey Administration
- Where
- United States
- Volunteers
- 1,242 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
A Culturally Informed Patient Navigation Program (CFPN) to Reduce Delays Between Diagnosis and Treatment in American Indian and Alaska Native Cancer Patients Living in Rural California
This clinical trial develops and tests whether a culturally informed patient navigation program, Community-Focused Patient Navigation (CFPN), works to reduce delays between diagnosis and treatment in American Indian and Alaska…
- Trial name
- NCT07332312
- Testing
- Discussion, Educational Intervention, Electronic Health Record Review
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Solid Tumor, Solid Tumor, Adult
Psychotherapy Intervention for Latinos With Adv Cancer
The purpose of this study is to adapt a counseling intervention called Meaning Centered Psychotherapy to make it culturally relevant for Latinos. Cancer affects patients and their loved ones.
- Conditions
- Solid Tumor, Solid Tumor, Adult, Solid Tumor, Unspecified, Adult
- Trial name
- NCT04537936
- Testing
- Meaning Centered Psychotherapy for Latinos, Functional Assessment of Cancer Therapy - Spiritual Well-Being Scale, Meaning Centered Psychotherapy for Latinos for Waitlist Control Patients
- Where
- 4 sites in United States, Puerto Rico
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
B7H3, CD276 Affibody
Study on B7-H3 Targeted Affibody Radioligand Probes for PET Imaging of Solid Tumors
Based on [68Ga]B7H3 Affibody-BCH, this study investigates its radioactive uptake and imaging capabilities in tumor patients, with the aim of establishing a correlation between radioactive uptake and B7-H3 receptor expression.
- Conditions
- B7H3, CD276 Affibody, PET/CT Imaing
- Trial name
- NCT06454955
- Testing
- [68Ga] B7H3 Affibody-BCH
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Cancer Hospital & Institute
Unspecified Adult Solid Tumor, Protocol Specific
Promoting Physical Activity In After-School Programs for Urban Adolescents
RATIONALE: Physical activity may lower the risk of some types of cancer and other chronic diseases. PURPOSE: This clinical trial is studying ways to increase physical activity in urban adolescents who attend after-school programs.
- Trial name
- NCT00301158
- Testing
- exercise intervention, counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Montclair State University
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Evaluation of Satisfaction With Quality of Care on the Palliative Care Unit
This study examines the difference between the quality of care patients receive with palliative care consult services and the palliative care unit.
- Trial name
- NCT02686411
- Testing
- Survey Administration
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cancer, Tumors
Detection of Tumor DNA in Blood Samples From Cancer Patients
The aim of this study is to employ genomic detection methodologies to measure the relative amount of tumor nucleic acids in the blood of a cancer patient with diagnosed metastatic disease that is either commencing, currently…
- Trial name
- NCT02288754
- Testing
- Blood test
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Lexent Bio, Inc.
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Virtual Reality Experiences for Anxiety and Pain Control
This trial studies the impact of virtual reality experiences on anxiety before surgery and pain after surgery. The goal of this study is to examine how different virtual reality experiences may help reduce anxiety and improve…
- Trial name
- NCT04759183
- Testing
- Survey Administration, Virtual Reality Game, Virtual Reality Meditation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Malignant Tumors
The Predictive Value of Serum Histone Succinylation in Malignant Solid Tumors
In recent years, advances in protein post-translational modification (PTM) research have revealed histone succinylation as a novel epigenetic modification mechanism critically involved in tumor initiation, progression, and…
- Trial name
- NCT07132606
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Yinghua Ji
Advanced Solid Tumor, Head and Neck Squamous Cell Carcinoma
Study of CHS-114 in Participants With Advanced Solid Tumors
This is a Phase 1, open-label, first-in-human, dose-escalation and expansion study of CHS-114, a monoclonal antibody that targets CCR8, as a monotherapy in patients with solid tumors.
- Trial name
- NCT05635643
- Testing
- CHS-114, toripalimab
- Where
- 12 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Coherus Oncology, Inc.
Esophageal Carcinoma, Lung Carcinoma
Yoga Program for Improving the Quality of Life in Couples Coping With Cancer
This clinical trial seeks to learn if a yoga program can improve physical performance, quality of life and symptom burden in cancer patients who are undergoing radiation therapy, and their partners.
- Conditions
- Esophageal Carcinoma, Lung Carcinoma, Malignant Head and Neck Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04607590
- Testing
- Best Practice, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tumor, Solid
Analysis of Chemical Pattern Exhaled by Different Neoplasms Through Chemoresistive Nanostructured Sensors
The aim of the study is to identify a pattern of chemoresistive sensors able to recognise the presence of a tumoral pathology from a health state through the analysis of Volatile Organic Compounds inside the specimen.
- Trial name
- NCT03929185
- Testing
- blood analysis with SCENT B1, tissue analysis with SCENT B1
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Adult Solid Neoplasm, Lymphoma
Improving Communication in Older Cancer Patients and Their Caregivers
Over 60% of cancers occur in older persons, and the number of older persons with cancer is expected to grow as the population ages.
- Trial name
- COACH (NCT02107443)
- Testing
- Geriatric Assessment Summary, Geriatric Assessment Targeted Recommendations, Geriatric Assessment (GA)
- Where
- 19 sites in United States
- Volunteers
- 546 people, healthy volunteers welcome
- Sponsor
- Supriya Mohile