Clinical trials: Neoplasms, Thyroid
Recurrent Thyroid Cancer, Stage IV Follicular Thyroid Cancer
Romidepsin in Treating Patients With Recurrent and/or Metastatic Thyroid Cancer That Has Not Responded to Radioactive Iodine
This phase II trial is studying how well romidepsin works in treating patients with recurrent and/or metastatic thyroid cancer that has not responded to radioactive iodine.
- Conditions
- Recurrent Thyroid Cancer, Stage IV Follicular Thyroid Cancer, Stage IV Papillary Thyroid Cancer
- Trial name
- NCT00098813
- Testing
- romidepsin, laboratory biomarker analysis, positron emission tomography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Cancer Institute (NCI)
Lung Cancer, Breast Cancer
Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis
The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches.
- Conditions
- Lung Cancer, Breast Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT06363123
- Where
- 4 sites in China
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Thyroid Cancer, Thyroid Nodule
AI-Assisted Ultrasound Review Before Thyroid Surgery
This prospective, single-center, single-arm study evaluates a locked artificial intelligence (AI) system as a surgeon-led second-read tool before thyroid surgery.
- Trial name
- NCT06498674
- Testing
- Locked AI-Assisted Thyroid Ultrasound Repeat Examination and Review
- Where
- China
- Volunteers
- 515 people
- Sponsor
- Fujian Medical University
Differentiated Thyroid Cancer
The Prognostic Value of Post Thyroidectomy 99mTCpertechnetate Thyroid Scan in Patient With Differentiated Thyroid Cancer
The aim of this study is to evaluate the prognostic value of postoperative99mTc-pertechnetate scanning in patients with DTC.
- Trial name
- NCT04563780
- Testing
- 99mTC pertechnetate thyroid scan
- Where
- Egypt
- Volunteers
- 113 people
- Sponsor
- Assiut University
Thyroid Neoplasms
Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy
The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy.
- Trial name
- NCT02826746
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Ajou University School of Medicine
Thyroid Carcinoma, Hypothyroidism
The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma
The purpose of this study is to evaluate whether taking thyroid hormone medication with beverages other than water, decreases absorption of the medication by the intestine.
- Trial name
- NCT01707056
- Testing
- Black Coffee, Coffee with Milk, Black Tea
- Where
- 3 sites in United States
- Sponsor
- Medstar Health Research Institute
Papillary Thyroid Cancer, Pediatric Cancer
Targeted Therapy to Increase RAI Uptake in Metastatic DTC
Papillary thyroid cancer (PTC) is a common type of differentiated thyroid cancer (DTC) in children and represents the second most common cancer in adolescent females.
- Conditions
- Papillary Thyroid Cancer, Pediatric Cancer, Differentiated Thyroid Cancer
- Trial name
- NCT05024929
- Testing
- Whole body scan
- Where
- 9 sites in United States, Australia
- Volunteers
- 32 people
- Sponsor
- Children's Hospital of Philadelphia
Differentiated Thyroid Gland Carcinoma, Recurrent Thyroid Gland Carcinoma
Sunitinib Malate in Treating Patients With Thyroid Cancer That Did Not Respond to Iodine I 131 and Cannot Be Removed by Surgery
This phase II trial studies how well sunitinib malate works in treating patients with thyroid cancer that did not respond to iodine I 131 (radioactive iodine) and cannot be removed by surgery.
- Conditions
- Differentiated Thyroid Gland Carcinoma, Recurrent Thyroid Gland Carcinoma, Refractory Thyroid Gland Carcinoma, Stage III Thyroid Gland Follicular Carcinoma AJCC v7
- Trial name
- NCT00381641
- Testing
- Laboratory Biomarker Analysis, Pharmacogenomic Study, Sunitinib
- Where
- 17 sites in United States
- Volunteers
- 63 people
- Sponsor
- National Cancer Institute (NCI)
Thyroid Carcinoma, Robot Surgery
Comparative Study of Robot BABA Approach and Chest Breast Approach for Lateral Neck Dissection
Objective to compare the advantages and disadvantages of robotic and conventional endoscopic thyroidectomy for thyroid cancer.
- Conditions
- Thyroid Carcinoma, Robot Surgery, Endoscopic Surgery
- Trial name
- NCT03500666
- Testing
- Robot, Total endoscopic
- Where
- 2 sites in China
- Volunteers
- 10 people
- Sponsor
- Fujian Medical University
Differentiated Thyroid Carcinoma
OnT4-Thyroglobulin Assay Before rhTSH-Aided Radioiodine Ablation
Thyroidectomy followed by administration of large activities of 131-iodine (131I) is the treatment of choice for differentiated thyroid carcinoma (DTC).
- Trial name
- NCT00439127
- Volunteers
- 28 people
- Sponsor
- Oncology Institute of Southern Switzerland
Differentiated Thyroid Cancer
Tracheal Replacement Using A Cryopreserved Aortic Allograft For R0 Resection In Locally Advanced Thyroid Cancer (TRITON 02 Tracheal Replacement In ThyrOid caNcer)
Airway transplantation remains a great surgical and biological challenge. This is still an unsolved problem for patients in therapeutic impasse because of major tracheobronchial lesions requiring surgical resection and airway…
- Trial name
- TRITON 02 (NCT07823686)
- Testing
- Tracheal replacement using a cryopreserved aortic allograft for R0 resection in locally advanced thyroid cancer, Conventional treatment
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adrenocortical Carcinoma
The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma
This work will evaluate the effects of mitotane treatment on serum protein concentrations in patients treated for ACC with mitotane therapy and compare them to patients with an adrenal neoplasm and pregnant cohort.
- Trial name
- MitoS-FP (NCT05344027)
- Testing
- Mitotane
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Lacrimal Apparatus Disease
Lacrimal Drainage System Obstruction Associated to Radioactive Iodine Therapy for Thyroid Carcinoma
The radioactive radioiodine therapy (Na131I) for the treatment of differentiated thyroid carcinoma is a procedure used for ablation of remaining thyroid tissue after thyroidectomy and metastases.
- Trial name
- NCT01579344
- Testing
- Radioiodine therapy
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Fabricio Lopes da Fonseca
Thyroid Nodule
Percutaneous Ethanol Injection for Benign Cystic Thyroid Nodules
Use of ethanol injection in treatment of cystic thyroid nodule
- Trial name
- NCT03257930
- Testing
- ethanol injection
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- hassan harby mohamed
Breast Cancer, Prostate Cancer
A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer
The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT).
- Conditions
- Breast Cancer, Prostate Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT07225309
- Testing
- Meaning-Centered Psychotherapy for Latinos /MCP-L
- Where
- 2 sites in United States, Mexico
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cancer
A Dose Escalation and Cohort-Expansion Study of Oral eFT508 in Subjects With Advanced Solid Tumors
This clinical trial is a Phase 1-2, open-label, sequential-group, dose-escalation and cohort-expansion study evaluating the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of daily oral administration of eFT508.
- Trial name
- NCT02605083
- Testing
- eFT508
- Where
- 4 sites in United States
- Volunteers
- 66 people
- Sponsor
- Effector Therapeutics
Melanoma, Glioma
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
The purpose of this clinical trial is to learn the safety and effects of the study medicine (PF-07799544) alone or in combination as a potential cancer treatment for adults with advanced solid tumors.
- Conditions
- Melanoma, Glioma, Thyroid Cancer, Non-Small Cell Lung Cancer
- Trial name
- NCT05538130
- Testing
- PF-07799544, PF-07799933
- Where
- 66 sites in United States, Australia and 5 more
- Volunteers
- 148 people
- Sponsor
- Pfizer
Papillary Thyroid Carcinoma
Diagnostic Accuracy of Fluorodeoxyglucose-18 PET in the Evaluation of RPTC With Patient's Raised Thyroglobulin Level
This research will employ cross-sectional analytical to determine diagnostic accuracy of Flourodeoxyglucose-18 Positron Emission Computed Tomography in the evaluation of Recurrent Papillary Thyroid Carcinoma with patient's raised…
- Trial name
- NCT07062211
- Where
- Pakistan
- Volunteers
- 39 people
- Sponsor
- Superior University
Thyroid Cancer, Large Language Models
Evaluation of an Artificial Intelligence-enabled Clinical Assistant to Support Thyroid Cancer Management
This study aims to evaluate the clinical feasibility of adopting artificial intelligence (AI)-based models to improve clinical management of thyroid cancer.
- Trial name
- NCT07234539
- Testing
- AI-enabled clinical assistant
- Where
- 2 sites in Hong Kong
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Papillary Thyroid Carcinoma
Retro-Auricular Single-Site Endoscopic to Papillary Thyroid Carcinoma
The goal of this non randomized control clinical research study is to compare the cosmetic outcomes and efficiacy of retro-auricular single-site endoscopic thyroid lobectomy and central lymph node dissection against conventional…
- Trial name
- NCT05263141
- Testing
- retro-auricular single-site endoscopic thyroidectomy, traditional open surgery thyroidectomy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.