Clinical trials: Neoplasms, completed
Colorectal Cancer, Colon Cancer
DAILY: Vitamin D, Aspirin, ExercIse, Low Saturated Fat Foods StudY in Colorectal Cancer Patients With Minimal Residual Disease
To learn if lifestyle changes (such as diet and exercise) combined with daily aspirin and vitamin D can affect the likelihood of advanced colorectal cancer coming back (recurring)
- Trial name
- NCT05036109
- Testing
- Aspirin, Vitamin D, Diet
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- M.D. Anderson Cancer Center
Non-muscle Invasive Bladder Cancer
Validation of a Urine-based Assay With Genomic Markers for Predicting Recurrence for Non-muscle Invasive Bladder Cancer
A study to validate, in a prospective manner, the ability of the predefined Genomic Health bladder cancer assay to detect recurrence in patients undergoing surveillance for non-muscle invasive bladder cancer.
- Trial name
- NCT02969109
- Where
- United States
- Volunteers
- 417 people
- Sponsor
- Genomic Health®, Inc.
Soft Tissue Sarcoma
Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft TIssue Sarcoma After Pre-treatment Failure
The purpose of this study is to assess efficacy and safety of LBH589 - Panobinostat®, a potent HDACi, in patients with advanced STS who experiment disease progression after or during first-line chemotherapy.
- Trial name
- ESTIM-LBH (NCT01136499)
- Testing
- LBH589 (Panobinostat®)
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Centre Leon Berard
Leukemia, Myelodysplastic Syndromes
Doxercalciferol in Treating Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
RATIONALE: Doxercalciferol may improve low blood cell counts and decrease the need for blood transfusions and may be an effective treatment for myelodysplastic syndrome or chronic myelomonocytic leukemia.
- Conditions
- Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
- Trial name
- NCT00052832
- Testing
- doxercalciferol
- Where
- United States
- Sponsor
- University of Wisconsin, Madison
Breast Cancer
Evaluation of a 3-D Tomosynthesis Mammography System Used in Conjunction With Conventional 2-D Digital Mammography
This was a multi-center, prospective clinical trial in which the subject was her own control. Approximately 950-1400 female subjects were enrolled at five (5) sites in the United States.
- Trial name
- NCT00754598
- Testing
- Tomosynthesis digital mammography imaging system
- Where
- 5 sites in United States
- Volunteers
- 1,183 people
- Sponsor
- Hologic, Inc.
Biliary Tract Cancer
A Phase I Study of Adjuvant Chemotherapy With GC in Biliary Tract Cancer Undergoing Resection Without Major Hepatectomy
To decide maximum tolerated dose and recommended dose of treatment using gemcitabine plus cisplatin combination therapy in patients with biliary tract cancer undergoing resection without major hepatectomy.
- Trial name
- NCT01297998
- Testing
- gemcitabine , cisplatin
- Where
- Japan
- Volunteers
- 24 people
- Sponsor
- Kansai Hepatobiliary Oncology Group
Polycystic Ovary Syndrome, Gestational Diabetes Mellitus
Screening for GDM in Women With PCOS and Controls
Women with polycystic ovary syndrome (PCOS) are often insulin resistant. During pregnancy, insulin sensitivity decreases. The investigators examine glucose metabolism during oral glucose tolerance test and the incidense of…
- Trial name
- NCT02183558
- Testing
- OGTT by randomization, OGTT by indication
- Where
- Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Brain Cancer, Arthritis, Rheumatoid
Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis
The purpose of this study is to determine whether [18F]FHBG is suitable for use as an imaging probe in cancer or rheumatoid arthritis patients enrolled in cell or gene therapy trials.
- Conditions
- Brain Cancer, Arthritis, Rheumatoid, Central Nervous System Neoplasms, Glioma
- Trial name
- NCT00185848
- Testing
- [18F]FHBG
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Sanjiv Sam Gambhir
Nasopharyngeal Neoplasms, Carcinoma
Docetaxel in Combination With Cisplatin-5-fluorouracil for the Induction Treatment of Nasopharyngeal Carcinoma in Children and Adolescents
The primary objective is to estimate the Complete Response rate of docetaxel to the combination of cisplatin-5-fluorouracil (TCF) compared to cisplatin-5-fluorouracil (CF) in the Induction treatment of Nasopharyngeal Carcinoma…
- Trial name
- NCT00565448
- Testing
- docetaxel, cisplatin, 5-fluorouracil
- Where
- 26 sites in Algeria, Brazil and 12 more
- Volunteers
- 75 people
- Sponsor
- Sanofi
Myeloproliferative Neoplasms
A Phase II Study of SGI-110 in Philadelphia-Negative Myeloproliferative Neoplasms
This is an open label single-arm, single-institution stud to evaluate the efficacy and safety of SGI-110 in Philadelphia chromosome negative (Ph-) Myeloproliferative Neoplasms (MPN) (excluding PV, ET and primary/secondary…
- Trial name
- NCT03075826
- Testing
- SGI-110
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Weill Medical College of Cornell University
Colorectal Cancer
Study of Gamma Interfereon in Metastatic Colorectal Carcinoma
The purpose of this study is to evalute the response and toxicity of metastatic colorectal cancer patients to the regimen of gamma interferon added to bolus and infusional 5-fluorouracil and leucovorin (GFL) with or without…
- Trial name
- GFL (NCT00786643)
- Testing
- 5-Fluorouracil, Leucovorin (LV), Gamma-Interferon-1b (IFN-γ)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Accelerated Community Oncology Research Network
Cervical Cancer
Comparative Study of Different Neoadjuvant Therapies Before Radical Hysterectomy in Stage Ib2-IIa2 Cervical Cancer
For stage Ib2-IIa2 cervical cancer patients, neoadjuvant therapy followed by radical hysterectomy and pelvic lymphadenectomy is one of the managements.
- Trial name
- NCT03243825
- Testing
- combination group, chemotherapy group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Chinese Academy of Medical Sciences
Geriatric Cancer Patients
A Chatbot-Powered G8 Screening Intervention to Facilitate Referrals to a Comprehensive Geriatric Assessment Among Older Adults With Cancer
In this prospective quality improvement study, we will develop and evaluate the feasibility and acceptability of an online patient self-reported G8 screening tool which will allow us to efficiently identify G8 positive older…
- Trial name
- NCT05535140
- Testing
- G8 Screening Tool
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Jefferson University
Pediatric Cancer
The Effect of Biofeedback-Based Virtual Reality Game on Children
The needles of port catheters, which are often used in childhood cancer treatment, must be changed every 5-7 days, which causes pain, anxiety, and fear in children every 5-7 days In recent years, the usage of virtual reality has…
- Trial name
- NCT05585840
- Testing
- Biofeedback-based virtual reality game
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Koç University
Advanced Solid Tumors
A Phase 1 Study of the Clinical and Immunologic Effects of ALT-803 in Patients With Advanced Solid Tumors
The proposed clinical trial is a phase I, open-label, multi-center, dose-escalation study of ALT-803 in patients with surgically incurable advanced solid tumors: melanoma, renal cell, non-small cell lung and squamous cell head…
- Trial name
- NCT01946789
- Testing
- ALT-803
- Where
- 5 sites in United States
- Volunteers
- 26 people
- Sponsor
- Altor BioScience
Metastatic Prostate Cancer, Castration-resistant Prostate Cancer
I-131-1095 Radioligand Plus Enzalutamide vs Enzalutamide for mCRPC That Progressed During Abiraterone (ARROW).
This clinical trial was done to show whether a radioactive drug (I-131-1095) that binds to prostate-specific membrane antigen (PSMA) is useful in treating metastatic prostate cancer that is positive for PSMA.
- Conditions
- Metastatic Prostate Cancer, Castration-resistant Prostate Cancer, Prostatic Neoplasm, Cancer of the Prostate
- Trial name
- ARROW (NCT03939689)
- Testing
- I-131-1095, Enzalutamide
- Where
- 27 sites in United States, Canada
- Volunteers
- 120 people
- Sponsor
- Progenics Pharmaceuticals, Inc.
Squamous Intraepithelial Lesions of the Cervix, Human Papilloma Virus Infection
Papilocare®: Effects on Regression of Histologically Confirmed Cervical Intraepithelial Lesions 1 and Tolerance
clinical trial comparing the regression rate after 12 months of histologically confirmed cervical intraepithelial lesions 1 in 2 parallel groups.
- Conditions
- Squamous Intraepithelial Lesions of the Cervix, Human Papilloma Virus Infection, Cervix Lesion
- Trial name
- PAPILOCARE (NCT04624568)
- Testing
- PAPILOCARE
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
All Tumor Entities Treated With TKI Therapy
Reduction of Cancer Related Fatigue in Patients During TKI Therapy
The purpose of this pilot study is to determine the effects of a 12-week resistance training program on cancer related fatigue in cancer patients receiving tyrosine kinase inhibitor (TKI) therapy.
- Trial name
- RECAP (NCT01645150)
- Testing
- Progressive strength training
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- German Cancer Research Center
Ovarian Cancer, Peritoneal Cavity Cancer
Gene Therapy in Treating Patients With Advanced Recurrent or Persistent Ovarian Cancer or Primary Peritoneal Cancer
RATIONALE: Inserting the p53 gene into a person's cancer cells may improve the body's ability to fight cancer or make the cancer more sensitive to chemotherapy.
- Trial name
- NCT00003450
- Testing
- Ad5CMV-p53 gene
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Breast Neoplasm, Breast Cancer
Facilitating Adaptive Coping With Fear of Recurrence Among Breast Cancer Survivors
Fear of cancer recurrence (FCR) is a highly prevalent, disruptive, and under-treated problem for breast cancer survivors. This randomized controlled trial will test the efficacy of group-based Acceptance and Commitment Therapy…
- Conditions
- Breast Neoplasm, Breast Cancer, Breast Carcinoma, Malignant Neoplasm of Breast
- Trial name
- NCT05364450
- Testing
- Enhanced Usual Care, Acceptance Commitment Therapy, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Indiana University