Clinical trials: Neoplasms of Prostate
Prostate Cancer
Decision Making in Unaffected First-Degree Relatives of Prostate Cancer Patients
There are two parts to this study: (1) an information gathering phase leading to development of a new decision aid (phase 1); and (2) a study to test the newly developed decision aid (phase 2).
- Trial name
- NCT00815750
- Testing
- Information Gathering, Decision Aid
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Prostate Cancer
Periperal Blood Lymphocytes During Prostate RT
Right now it is not possible to predict which patients are going to react more to RT. Many things could affect patient's response to radiation.
- Trial name
- NCT01899391
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Erectile Dysfunction, Prostate Cancer
Erectile Recovery After Robotic-Assisted Laparoscopic Prostatectomy
The study is a prospective, randomized, double-blind, placebo-controlled drug study to evaluate the pattern of erectile function recovery after robotic assisted laparoscopic prostatectomy (RALP).
- Trial name
- NCT03406169
- Testing
- Sildenafil 25 MG Oral Tablet, Pentoxifylline
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Prostate Cancer
Improving Engagement From Underserved Communities With Prostate Cancer Genetics Services
Earlier work explored barriers and facilitators to accessing prostate cancer screening, particularly in underserved communities, and provided valuable insights to build upon.
- Trial name
- INCLUDE PC (NCT07407686)
- Testing
- Surveys, Semi-structured interviews and focus groups
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Metastatic Castration Resistant Prostate Cancer
A Study Evaluating HC-1119 Single-Dose Pharmacokinetics and Effect of Food on Its Pharmacokinetics
This is a phase I study evaluating HC-1119 single-dose pharmacokinetics and effect of food on its pharmacokinetics in healthy Chinese adults.
- Trial name
- NCT03776968
- Testing
- HC1119
- Where
- China
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Hinova Pharmaceuticals Inc.
Carcinoma Prostate
Efficacy of Diclofenac Suppository for Pain Control in Ultrasound Guided Biopsy of Prostate
Transrectal ultrasound guided biopsy of prostate (TRUS-Bx) is widely used as accepted mode of investigation for prostate cancer in current urology practice.
- Trial name
- NCT01939743
- Testing
- Diclofenac suppository plus lidocaine gel, Lidocaine gel only
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Aromatherapy, Prostate Cancer
Aromatherapy on Pain and Anxiety of the Patients Undergoing Prostate Biopsy
The study included 120 male patients who would undergo a prostate biopsy. Patients were divided into 3 groups as placebo group (n = 40), Levander group (N = 40), and Frankincense group (n = 40).
- Conditions
- Aromatherapy, Prostate Cancer, Anxiety
- Trial name
- NCT06119438
- Testing
- Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin Training and Research Hospital
Prostate Cancer, Nerve Sparing Prostatectomy
Pilot Study of VTI Doppler Probe Use to Identify Neurovascular Bundle During Prostate Surgery
This study is designed to evaluate the use of a disposable laparoscopic Doppler probe in robotic assisted prostatectomies. The Vascular Technology, Inc.
- Trial name
- NCT01794936
- Testing
- VTI Probe
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Columbia University
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Prostate Cancer
The Effect of Endurance Training on Body Composition and Insulin Sensitivity in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
The purpose of the present study is to investigate if endurance training can be used as a therapeutic action against the adverse metabolic disturbances and unfavourable changes in body composition that accompany the androgen…
- Trial name
- NCT01676480
- Testing
- Endurance training
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Inge Holm
Prostate Cancer, Sexual Dysfunctions, Psychological
Innovations in the Treatment of Sexual Health Post Prostate Cancer Treatment: Comparing Mindfulness vs. CBT
Up to 90% of men experience sexual difficulties after receiving treatment for prostate cancer (PC), which can negatively affect their intimate relationships and overall quality of life.
- Conditions
- Prostate Cancer, Sexual Dysfunctions, Psychological, Sexual Dysfunction, Physiological, Sexual Dysfunction Male
- Trial name
- INTROSPPECT (NCT03365518)
- Testing
- Cognitive Behavioural Therapy (CBT), Mindfulness-Based Therapy
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Prostate Cancer, Endometriosis
A Phase 1 Study to Evaluate the Effects of Fluconazole and Atorvastatin on the Pharmacokinetics of TAK-385 in Healthy Subjects
This is a nonrandomized, open-label, fixed-sequence, 2-arm study designed to assess the effect of multiple doses of fluconazole or atorvastatin on the single-dose pharmacokinetics of TAK-385 in healthy adult subjects.
- Trial name
- NCT02093390
- Testing
- TAK-385, Fluconazole, Atorvastatin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Millennium Pharmaceuticals, Inc.
Prostate Cancer
Comparison of a Novel Leuprolide With Market Leuprolide
This is a single dose, randomized, single blind, parallel group study to evaluate the testosterone suppressive effect in healthy male volunteers of a novel leuprolide acetate 3.75mg depot vs market reference leuprolide acetate…
- Trial name
- NCT03662958
- Testing
- Lutrate, Enantone
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Prostate Cancer, Rectal Cancer
Video Analysis of Errors and Technical Performance Within Minimally Invasive Surgery Short Title: Video Analysis in Minimally Invasive Surgery (VAMIS)
Despite the high volumes, advanced minimally invasive surgery is non-standardised and variations often occur in surgical technique, performance, delivery, team communication, and surgical approach.
- Trial name
- VAMIS (NCT05279287)
- Testing
- Video and kinematic data recording of minimally invasive surgical procedure
- Where
- 5 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Griffin Institute
Prostate Cancer, Kidney Cancer
Preop Laxatives in Robotic Urologic Surgery
Minimally-invasive surgery, either laparoscopic or robotic, is commonly used in urology. Several urologic procedures including prostatectomy, radical nephrectomy, and partial nephrectomy are now commonly performed robotically.
- Conditions
- Prostate Cancer, Kidney Cancer, Constipation
- Trial name
- NCT05805436
- Testing
- Polyethylene Glycol 3350
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Chad R. Tracy
Head and Neck Cancer, Prostate Cancer
Application of High Resolution Diffusion-weighted MR Imaging Pulse Sequence in Head and Neck, and Prostate Cancers
Magnetic resonance imaging (MRI) is a diagnostic study that makes pictures of organs of the body using magnetic field and radio frequency pulses that can not be felt.
- Trial name
- NCT01535898
- Testing
- MRI scanner with sequence
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Carcinoma of Prostate
PSMA PET Registry (18F-DCFPyL)
The purpose of the Princess Margaret Cancer Centre PSMA registry is to assess the contribution of 18F-DCFPyL (PSMA) PET imaging (PET/MR or PET/CT) to the management of patients with prostate cancer (PCa).
- Trial name
- PM-PPR (NCT03535831)
- Testing
- 18F-DCFPyL
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Preference, Patient, Pharmacist-Patient Relations
Preferences of Patients Treated With Oral Cancer Drugs and Informal Caregivers for Pharmaceutical Consultation in Hospital
To ensure the safe use of oral anticancer drugs, oncology pharmacy consultations (OPCs) have been established in France. Their goal is to provide the patient with the means to identify, prevent and limit adverse effects and to…
- Conditions
- Preference, Patient, Pharmacist-Patient Relations, Caregiver, Cancer
- Trial name
- IMPLICATION (NCT05970471)
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Preventive Screening, Prostate Cancer
Understanding and Discouraging Overuse of Potentially Harmful Screening Tests
Most prevention efforts focus on promoting services (e.g. vaccination, screening tests). While some of these services have clear net benefit, many instead have possible or clear net harm.
- Conditions
- Preventive Screening, Prostate Cancer, Osteoporosis, Colorectal Cancer
- Trial name
- NCT01694784
- Testing
- Quantitative Information Sheet, Qualitative Information Sheet, Narrative Information Sheet
- Where
- United States
- Volunteers
- 775 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Prostate Cancer, Urologic Cancer
The Man Van Project
National Health Service (NHS) England has commissioned The Royal Marsden Hospital NHS Foundation Trust to run a novel mobile clinical outreach service called 'Man Van' with the aim of enabling male patients' easy access to care…
- Conditions
- Prostate Cancer, Urologic Cancer, Urologic Diseases, Bladder Cancer
- Trial name
- MV (NCT06357416)
- Testing
- MV-POCT Sub-study, Main Man Van Group Sub-study (MV-Eco), MV-QualQ Sub-study
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust