Clinical trials: Nephrolithiasis, Calcium Oxalate
Kidney Stone
Thulium Fiber Laser Prospective Trial
This is a multi-center, prospective clinical trial to assess the effect of TFL for the lithotripsy of kidney stones.
- Trial name
- TFL (NCT05814133)
- Testing
- Thulium Fiber Laser
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
RENAL CALCULI
Safety and Efficacy of Herbmed Plus in Patients withRenal Calculi
More specifically, the present invention relates to a 'Herbal Preparation' that is useful for Treatment of Renal calculi Reduction in the stone size \& surface area The expulsion of stone Decreased need of…
- Trial name
- HerbmedPlus (NCT01355341)
- Testing
- HERBMED PLUS
- Where
- India
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Amai Charitable Trust
Kidney Stones
Oxalate-Driven Host Responses in Kidney Stone Disease
This study is looking to understand the role of oxalate on kidney stone development and immunity. This study will enroll healthy participants and participants with calcium oxalate kidney stones (CaOx KS).
- Trial name
- NCT05417568
- Testing
- Low Oxalate Diet, High Oxalate Diet
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Calculi, Ureteral Calculi
Study of Ketorolac Versus Opioid for Pain After Endoscopy
A double blind randomized controlled trial designed to compare pain control and safety with ketorolac and oxycodone in the post-operative setting for patients undergoing ureteroscopy for treatment of urinary stones.
- Trial name
- SKOPE (NCT03888144)
- Testing
- Oxycodone, Ketorolac
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Renal Stone, Treatment Side Effects
Efficacy and Safety of Narrow Focus (F1) Versus Wide Focus (F3) of Shock Wave Lithotripsy (SWL) for Renal Calculi
This study aims to compare the narrow focus (F1) versus the wide focus (F3) in terms of the efficacy of Shock Wave Lithotripsy (SWL) in the management of renal calculi 1-2 cm and their injurious effect on the kidney.
- Trial name
- NCT04759599
- Testing
- Shock Wave Lithotripsy (SWL)
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Benha University
Kidney Stone
Can Shear Wave Elastography Predict the Success of ESWL: a Prospective Study
Can Shear Wave Elastography predict the success of Shock-Wave Lithotripsy used in renal stones treatment ? A prospective study
- Trial name
- NCT05995652
- Testing
- elastography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Abdelrahim Elsherbiny
Chronic Kidney Disease, Nephrolithiasis
Kidney Sodium Functional Imaging
The corticomedullary gradient is largely responsible for developing the gradients that are needed to concentrate urine (more solutes and less water).
- Conditions
- Chronic Kidney Disease, Nephrolithiasis, ADPKD
- Trial name
- NCT05014178
- Testing
- Sodium-23 MRI
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Pneumothorax, Intestinal Obstruction
The Impact of Artificial Intelligence-Assisted X-ray Interpretation on Radiologists' Diagnostic Performance
This study tests whether an artificial intelligence (AI) tool helps radiologists read X-rays more accurately. Radiologists read X-rays to find diseases such as pneumonia, bone fractures, and abdominal problems.
- Conditions
- Pneumothorax, Intestinal Obstruction, Spondylolysis, Renal Calculus
- Trial name
- NCT07870928
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Nephrolithiasis, Urinary Tract Infections
A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
When patients are going to have surgery to remove large kidney stones (percutaneous nephrolithotomy [PCNL]), it is not clear whether the patients benefit from a course of prophylactic preoperative oral antibiotics; currently both…
- Trial name
- NCT02384200
- Testing
- nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin
- Where
- 8 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Kidney Calculi, Calcium Oxalate Kidney Stones
Evaluating the Vitamin K2 Status of Calcium-based Stone Formers
This is an observation, single site-study with one study visit during which all data and samples will be collected. Study participants will be asked to provide blood, urine, and fecal samples so that the investigators may study…
- Conditions
- Kidney Calculi, Calcium Oxalate Kidney Stones, Vitamin K 2, Human
- Trial name
- NCT05081960
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Stone
A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (IAU-04)
ESWL and PNL are the two treatment modalities for kidney stones greater than 20 mm in the pediatric population. ESWL is non-invasive, does not require anesthesia and inexpensive, but its success rate may be lower, and require…
- Trial name
- NCT04317443
- Testing
- Super-mini percutaneous nephrolithotomy (SMP), Extracorporeal Shock Wave Lithotripsy (ESWL)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The International Alliance of Urolithiasis
Kidney Stone, Oxidative Stress
Lime Powder Regimen in Healthy Volunteers
The study aims to investigate the pharmacokinetic parameters and its antioxidative effects in Thai healthy men.
- Trial name
- LimePKphase1 (NCT01273025)
- Testing
- Lime powder regime
- Where
- Thailand
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Kidney Stone
Comparing Pneumatic Versus Ultra-sonic Percutaneous Nephrolithotomy in Large Kidney Stones
The purpose of this study is to determine which type of percutaneous nephrolithotomy is better in large kidney stones
- Trial name
- NCT02751281
- Testing
- Pneumatic percutaneous nephrolithotomy, Ultra-sonic percutaneous nephrolithotomy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Nephrolithiasis, Percutaneous
Comparison of Erector Spinae Plane Block and Intravenous Patient-controlled Analgesia in Percutaneous Nephrolithotomy
The primary purpose of this study was to compare the effects of erector spinal plane block (ESP) and IV patient-controlled analgesia (PCA) performed to provide analgesia in percutaneous nephrolithotomy surgeries on visual analog…
- Conditions
- Nephrolithiasis, Percutaneous, Analgesia, PCA
- Trial name
- NCT05845281
- Testing
- Bupivakain + deksametazon Adjuvant
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Kidney Stones, Urolithiasis, Hypocitraturia
Apple Cider Vinegar for the Prevention of Urinary Lithiasis (APUL)
The purpose of this study is to assess whether certain beverages can increase urinary citrate levels in healthy individuals with no history of kidney disease.
- Trial name
- APUL (NCT04073719)
- Testing
- Apple Cider Vinegar, Other Beverage
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Renal Stones
RIRS Versus ESWL for the Treatment of Renal Stones
To evaluate the effectiveness of RIRS (retrograde intrarenal surgery) and ESWL (extracorporeal shockwaves lithotripsy) in the treatment of renal stone ranging form 6 to 20 mm size.
- Trial name
- NCT02645058
- Testing
- RIRS, ESWL, Rigid and flexible ureteroscope
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Healthy Volunteers, Enteric Hyperoxaluria
Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects
The first stage of this study is a prospective, adaptive, Phase 1, first-in-human, randomized, controlled study evaluating safety, tolerability, and pharmacodynamics of NOV-001 in adult healthy volunteers.
- Trial name
- NCT04909723
- Testing
- NOV-001, NB1000S, NB2000P
- Where
- 20 sites in United States, Canada
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Novome Biotechnologies Inc
Kidney Stones
Percutaneous Nephrolithotomy Versus Extracorporeal Shock Wave Lithotripsy
The investigators main hypothesis is that the stone free rate will be much higher (95%) in patients treated with PCNL than patients treated with ESWL where stone free rate is (60%) to determine which treatment is safe and prevent…
- Trial name
- NCT00873054
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Kidney Stones, Nephrolithiasis
Effect of Diet Orange Soda on Urinary Lithogenicity
Beverages containing citrate may be useful in increasing urine citrate content and urine pH. Such changes in urine chemistry could help prevent kidney stones. Diet orange soda has more citrate than other similar beverages.
- Conditions
- Kidney Stones, Nephrolithiasis, Urolithiasis
- Trial name
- NCT01330940
- Testing
- Orange soda
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA New York Harbor Healthcare System