Clinical trials: Nephrolithiasis
Kidney Stone
A Novel Method for Retrograde Intrarenal Surgery (RIRS)
In this prospective randomised controlled study, investigators aims to evaluate the effect of 80 mg gentamicin added to 3 liters of irrigation fluid on stone free rate, intraoperative and postoperative complications during RIRS…
- Trial name
- NCT05202158
- Testing
- Addition of gentamicin to irrigation fluid during RIRS, Only irrigation fluid during RIRS
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Training and Research Hospital
Renal Stones, Retrograde Intrarenal Surgery
Safety of Thulium Fiber Laser Litothripsy in the Management of Large Renal Stones (>1000 mm³) and Factors Affecting Treatment Success
The aim of this study is to compare the efficacy and safety of Thulium Fiber Laser (TFL) litothripsy according to stone density and the factors affecting success in patients undergoing retrograde intrarenal surgery (RIRS) for…
- Conditions
- Renal Stones, Retrograde Intrarenal Surgery, Thulium Fiber Laser
- Trial name
- RIRS and TFL (NCT07153978)
- Testing
- Effectivity of TFL on large renal stone
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Muharrem Baturu
Urolithiasis
F-URS and Mini PCNL for Pediatric Urolithiasis
To compare RIRS versus mini-perc PNL in the management of medium size pediatric renal stones (10-20 mm) through a RCT.
- Trial name
- NCT06571617
- Testing
- Mini PCNL (mini percutaneous nephrolithotomy), RIRS (retrograde intrarenal surgery/ flexible URS)
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura University
Nephrolithiasis, Low Urine Volume
Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis
The primary objective of this study would be to determine whether utilization of this technology improves adherence to recommended increases in hydration for stone forming patients with low urine volume relative to standard…
- Trial name
- HidrateMe (NCT02938884)
- Testing
- HidrateSpark Water Bottle
- Where
- 4 sites in United States
- Volunteers
- 85 people
- Sponsor
- University of Minnesota
Kidney Stone, Nephrolithiasis
Comparison of SP TFL and Ho:YAG for RIRS Using 145 µm and 200 µm Fibers
The authors hypothesize that the RIRS using 150-microm Tm-fiber laser is superior than fiber with larger diameters, as 200-microm Tm-fiber laser or 200-microm holmium fiber laser, in such points as follows: decreasing surgery…
- Conditions
- Kidney Stone, Nephrolithiasis, Urolithiasis
- Trial name
- NCT04346485
- Testing
- SP TFL RIRS with 145 mcm fiber, SP TFL RIRS with 200 mcm fiber, Ho:YAG RIRS with 200 mcm fiber
- Where
- Russia
- Volunteers
- 105 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Ureteral Calculi, Renal Calculi
Intraureteral Lidocaine for Post-Ureteroscopy Pain
Ureteroscopy (URS) is minimally invasive procedure for management of renal stones. URS is often involves concomitant of an indwelling ureteral stents.
- Trial name
- NCT01450566
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Kidney Stone
Modified Supine vs Prone Position Pnl
perform a comparative randomized trial comparing the efficacy and safety of percutaneous nephrolithotomy (PCNL) in the prone and modified supine positions in management of complex renal stones
- Trial name
- NCT05379894
- Testing
- Percutaneous nephrolithotripsy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Renal Stone
Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy
Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%.
- Trial name
- NCT05725122
- Testing
- Extracorporeal shock wave lithotripsy, Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Services Hospital, Lahore
Urolithiasis, Stone;Renal
Mini- Percutaneous Nephrolithotomy Versus Standard Percutaneous Nephrolithotomy in the Treatment of Renal Stones.
The EUA Urolithiasis Guidelines Panel meta-analysis suggest that mPNL is at least as efficacious and safe as sPNL for the removal of renal calculi.
- Conditions
- Urolithiasis, Stone;Renal, Nephrolithiasis, PNL
- Trial name
- NCT04153461
- Testing
- MINI-PERCUTANEOUS NEPHROLITHOTOMY, STANDARD PERCUTANEOUS NEPHROLITHOTOMY
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Mansoura University
Kidney Stone
Effect of Cola on Urinary Stone Risk Factors
Examine the effects of cola on risks of kidney stones
- Trial name
- NCT00289120
- Testing
- Cola beverage, Deionized water
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Emory University
Kidney Stone
Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers
The aim of this study is to test the effect of a new drug on the composition of the urine in kidney stone patients. This new drug (Jardiance®, substance: empagliflozin) is currently approved in Switzerland for the treatment of…
- Trial name
- SWEETSTONE (NCT04911660)
- Testing
- Empagliflozin 25 MG
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Stone, Healthy
Oxalate and Citrate in Humans - Response to Citrate
This is a single-center study that aims to learn more about how two compounds found in food, oxalate and citrate, interact in the body and may influence a person's chances of forming kidney stones.
- Trial name
- NCT06944223
- Testing
- Kidney stone formers, Control cohort
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Ureteral Stent-Related Symptoms
Alfuzosin and Mirabegron for Double-J Stent Symptoms
This prospective randomized controlled trial investigates the effects of alfuzosin, mirabegron, and their combination on stent-related symptoms and outcomes in patients undergoing DJ stent placement after retrograde intrarenal…
- Trial name
- NCT07018934
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- University of Gaziantep
Primary Hyperoxaluria Type 3
Natural History of Patients With PH3 and a History of Stone Events
This is a natural history study of adults, adolescents, and children (starting at birth) with genetically confirmed primary hyperoxaluria type 3 (PH3) who have a history of stone events during the last 3 years and/or the presence…
- Trial name
- PHYOX-OBX (NCT04542590)
- Where
- 6 sites in United States, Canada and 3 more
- Volunteers
- 7 people
- Sponsor
- Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Kidney Calculi, Nephrolithiasis
Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones.
- Trial name
- NCT07749807
- Testing
- Nebulized Glubran 2-Assisted Tubeless PCNL, Conventional PCNL With Nephrostomy Tube
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Percutaneous Nephrolithotomy, Renal Stones
Effectiveness of US-Guided PCNL Different Positions in Renal Stones Treatment
The aim of this study is to compare the effectiveness of Ultrasound-Guided Percutaneous nephrolithotomyin different positions supine, prone positions and flank suspend supine position in renal stones treatment.
- Conditions
- Percutaneous Nephrolithotomy, Renal Stones, Ultrasound Therapy; Complications
- Trial name
- NCT05855057
- Testing
- Flank suspended supine position percutaneous nephrolithotomy, Supine percutaneous nephrolithotomy group, Prone percutaneous nephrolithotomy group
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Benha University
Kidney Calculi Nephrolithiasis Urolithiasis Renal Stone
Which Patinets Benefit More From Percutaneous Nephrolithotomy? A Location-Based Comparative Analysis of PCNL and RIRS for 1-2 cm Renal Stones
This prospective randomized controlled trial aims to compare the clinical efficacy and safety of Percutaneous Nephrolithotomy (PCNL) and Retrograde Intrarenal Surgery (RIRS) for renal stones measuring 10-20 mm.
- Trial name
- NCT07589153
- Testing
- Percutaneous Nephrolithotomy (PCNL), Retrograde Intrarenal Surgery (RIRS)
- Volunteers
- 110 people
- Sponsor
- Kırıkkale University
Kidney Stones
Ureteral Stent Length and Patient Symptoms
The Study of whether or not Ureteral Stent Length affects patient comfort after electro-shock wave treatment for kidney stones.
- Trial name
- NCT00288457
- Testing
- Ureteral Stent
- Volunteers
- 1 people
- Sponsor
- Emory University
Nephrolithiasis
The Success of Pediatric Percutaneous Nephrolithotomy
Between June 1997-June 2018, 573 pediatric patients underwent PCNL for renal stone disease by senior surgeons. Data was disunited into 2 groups.
- Trial name
- NCT04299204
- Testing
- Percutaneous nephrolitotomy
- Volunteers
- 553 people
- Sponsor
- Osmaniye Government Hospital
Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery
Mini Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Pediatric Renal Stones (10-30 mm)
This work aimed to compare the safety and efficacy of retrograde intrarenal surgery using single-use flexible ureteroscopy (FURS) with mini-percutaneous nephrolithotomy (PCNL) in children with renal stones measuring 10-30 mm.
- Conditions
- Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, Pediatric, Renal Stones
- Trial name
- NCT07836192
- Testing
- Mini percutaneous nephrolithotomy, Flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University