Clinical trials: Nephrolithotomy
Epidural Anesthesia, Percutaneous Nephrolithotomy (PCNL)
Predictors of Epidural Depth in Percutaneous Nephrolithotomy and Model Development
Accurate estimation of epidural depth is critical for safe epidural anesthesia during percutaneous nephrolithotomy (PCNL). Although various imaging modalities can predict epidural depth, they increase healthcare burden and are…
- Trial name
- NCT07697053
- Where
- China
- Volunteers
- 3,278 people
- Sponsor
- Tongji Hospital
Postoperative Pain
Quadratus Lumborum Block III Versus Peritubal Local Infiltration
Investigators compare post operative analgesic efficacy of peritubal local infiltration versus Quadratus Lumborum Block III . In patients undergoing Percutaneous Nephrolithotomy operation
- Trial name
- NCT04215705
- Testing
- Quadratus block versus peritubal local infiltration
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Renal Stone
Basic Hemodynamic Monitoring Reliability During Percutaneous Nephrolithotomy.
This prospective pre and post-quasi-descriptive single group interventional study will be done at urology and nephrology center -Mansoura University during the year 2019, for a 3-month duration, starting 1-2-2019 till 1-4-2019…
- Trial name
- NCT03828175
- Testing
- spinal anesthesia monitoring
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Nephrolithotomy, Percutaneous, Anesthetics, Local
Efficiency of Erector Spinae Plane Block For Patients Undergoing Percutaneous Nephrolithotomy
Investigators' goal is to determine whether Erector Spinae Plane Block would provide a better analgesia, help mobilization and early discharge or increase satisfaction for patients undergoing Percutaneous Nephrolithotomy(PNL).
- Conditions
- Nephrolithotomy, Percutaneous, Anesthetics, Local, Nerve Block, Erector Spinae Plane Block
- Trial name
- NCT03652103
- Testing
- Ultrasound Guided Erector Spinae Plane Block Catheterisation, Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bozyaka Training and Research Hospital
Percutaneous Nephrolithotomy
Application of One-handed Lithotripsy in Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy(PCNL) is a surgical method for upper urinary calculi.Traditional percutaneous nephrolithotomy usually requires the lithotripsy with the left hand holding the nephroscope and the right hand adjusting…
- Trial name
- NCT05661175
- Testing
- one-handed technique
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of University of South China
Health Related Quality of Life
Determinants of Health-related Quality of Life for Patients After Renal Lithotripsy: PNL Versus RIRS
Percutaneous nephrolithotomy (PNL) and Retrograde intrarenal surgery (RIRS) are well-established procedures for renal stone fragmentation; however, the morbidity, hospitalization, and lost work hours associated with these…
- Trial name
- NCT05851339
- Testing
- SF- 36 Questionnaire
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- South Valley University
Renal Parenchymal Loss After the Percutaneous Nephrolithotomy
Assessment of the Effects of Access Count in Percutaneous Nephrolithotomy on Renal Functions by Technetium-99M-Dimercaptosuccinic Acid Scintigraphy
In this study 37 patients who had undergone percutaneous nephrolithotomy were included. Preoperative DMSA scans were performed a day before the surgery, whereas postoperative scans were randomized by evaluating them before (n=25)…
- Trial name
- NCT01819753
- Testing
- Percutaneous nephrolithotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- TC Erciyes University
Kidney Calculi
Failed Insertion of Ureteral Access Sheath During Flexible Ureterorenoscopy
Percutaneous nephrolithotomy (PNL) is the gold standard recommended treatment technique for kidney stones larger than 20 mm. For kidney stones between 10 - 20 mm, both shock wave lithotripsy (SWL) or flexible ureterorenoscopy…
- Trial name
- NCT05911945
- Testing
- Flexible Ureterorenoscopy, Mini Percutaneous Nephrolithotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Haseki Training and Research Hospital
Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy
Supine vs. Prone Mini-PCNL in Children
Percutaneous nephrolithotomy (PCNL) is an established intervention for large or ESWL-resistant renal stones in pediatric populations.
- Conditions
- Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy, Prone Mini Percutaneous Nephrolithotomy
- Trial name
- SUPRO-PED (NCT07887945)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University Hospital
Stone, Kidney
Single-Shot With Dexmedetomidine Versus Continuous Ultrasound-guided Erector Spinae Plane Block for Postoperative Pain Control After Percutaneous Nephrolithotomy
The current study is designed to assess the efficacy of a single shot ESPB with Dexmedetomidineversus continuous ESPB in perioperative analgesia for PCNL. Both techniques are conducted for patients undergoing PCNL under GA.
- Trial name
- NCT04650737
- Testing
- single shot ESBP with dexmedtomidine, continous ESPB
- Volunteers
- 40 people
- Sponsor
- Cairo University
Kidney Stones, Urolithiasis, Hypocitraturia, Pain, Postoperative
Intertransverse Process Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is the preferred minimally invasive procedure for renal stones larger than 2 cm, staghorn calculi and complex stone burdens, but it is frequently associated with moderate-to-severe…
- Trial name
- NCT07908992
- Testing
- Ultrasound-guided intertransverse process block, Ultrasound-guided erector spinae plane block
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Blood Loss, Surgical
Can Trajectory Nor-epinephrine Infiltration Reduce Blood Loss During Percutaneous Nephrolithotomy (PCNL)?
during PCNL; A few milliliters of nor-epinephrine is injected into the intended tract after puncture of pelvicalyceal system and before its dilatation compared to injection of saline (placebo).
- Trial name
- NCT05035303
- Testing
- Nor-Epinephrine injection versus saline during PCNL
- Where
- 2 sites in Egypt
- Volunteers
- 140 people
- Sponsor
- Benha University
Post Operative Pain
Paravertebral Block for Percutaneous Nephrolithotomy
This study will compare post-operative pain levels in patients who receive paravertebral block prior to Percutaneous Nephrolithotomy (PCNL) surgery versus those who do not receive the block.
- Trial name
- PRONE (NCT01480102)
- Testing
- Group A-Paravertebral block, Group B- No block
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Loyola University
Nephrolithiasis
Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery.
There are two options for postoperative pain management: opioid and non-opioid analgesia. Pain outcomes will be compared in patients undergoing ureteroscopy and percutaneous nephrolithotomy by randomly administering opioid and…
- Trial name
- PO-NOA (NCT03584373)
- Testing
- Ketorolac Oral Tablet [Toradol], Acetaminophen, Oxycodone Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- Montefiore Medical Center
Kidney Stone, Kidney Calculi
Holmium Vs Trilogy Kidney Stones GUY's 1-2
The desire to reduce complications related to percutaneous access and morbidity related to tract size has led researchers to evaluate PCNL using smaller-caliber instruments. In this context, mini-PCNL has emerged.
- Conditions
- Kidney Stone, Kidney Calculi, Kidney Diseases
- Trial name
- TriHolmium (NCT04559321)
- Testing
- Fragmentation of calculi with 100 W Holmium laser or LithoClast Trilogy EMS and 1.5 mm x 440 mm probe, according to randomization.
- Where
- Mexico
- Volunteers
- 116 people
- Sponsor
- Hospital Regional de Alta Especialidad del Bajio
Kidney Stones
Flexible Ureteroscopy With a Flexible and Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for 1-2 cm Lower Pole Kidney Stones
This study, known as the FLAME Trial (Flexible ureteroscopy for Lower pole stones And Mini-pErcutaneous nephrolithotomy), is an international, multicenter, randomized, non-inferiority trial.
- Trial name
- FLAME (NCT07159035)
- Testing
- Flexible ureteroscopy with FANS, Mini-percutaneous nephrolithotomy (mini-PCNL)
- Where
- China
- Volunteers
- 640 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Shivering Control
Shivering Control After Percutaneous Nephrolithotomy
Aim of the study is comparing the effect of amino acid versus magnesium sulfate infusion on postoperative shivering in patients undergoing elective percutaneous nephrolithotomy surgery under general anesthesia.
- Trial name
- NCT04695613
- Testing
- Aminoacid, Magnesium sulfate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Kidney Stones
Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy
The Investigators objective is to compare the clinical efficacy of a single-day protocol with a short-course protocol for PCNL. The investigator hope is to reduce the use of possibly unnecessary prolonged antibiotic use, reduce…
- Trial name
- NCT02579161
- Testing
- cephalosporins, Fluoroquinolones, Clindamycin
- Where
- 2 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Analgesia
Comparison Of Epidural Analgesia Techniques In Percutaneous Nephrolithotomy With Surgical Pleth Index
Primary aim of this study is to evaluate affect of SPI guided antinociception on total intraoperative consumption of local aneshesics during analgesia.
- Trial name
- NCT05572164
- Testing
- TRADITIONAL EPIDURAL, DURAL PUNCTURE EPIDURAL
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Nephrolithiasis of Both Kidneys
Bilateral Percutaneous Nephrolithomy
The purpose of this study is to determine the effective regimen for definitive surgical therapy of bilateral kidney stones. It is unknown whether patients who undergo simultaneous bilateral percutaneous nephrolithotomy (PCNL)…
- Trial name
- NCT03924362
- Testing
- PCNL
- Where
- Canada
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of British Columbia