Clinical trials: Nephrolithotomy
Stone, Kidney
Endoscopic Combined Intrarenal Surgery Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones:
The aim of this study is to compare outcomes of endoscopic combined intrarenal surgery (ECIRS) with the multi-tract percutaneous nephrolithotomy for management of complex renal stones.
- Trial name
- NCT05460559
- Testing
- Group A (p-PCNL) procedure, Group B (s-ECIRS) procedure
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Kidney Stone
A RCT to Evaluate the Efficacy and Safety of Automated Needle Targeting (ANT-X) System Compared to Traditional Free Hand Puncture for Renal Access in Percutaneous Nephrolithotomy (PCNL)
Objectives: This study aims to determine if the device provides an advantage over traditional free hand puncture by comparing the number of attempts required to obtain access, time to achieve access, radiation exposure to patient…
- Trial name
- NCT05213702
- Testing
- Renal Calyx punture with traditional free hand or ANT-X device
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Renal Stones
Management of Medium Sized Renal Stones
Urinary stone disease is a common urological condition that affects millions of people worldwide, often leading to significant morbidity and healthcare costs.
- Trial name
- NCT06720311
- Testing
- Modified Tubeless Super-Mini Percutaneous Nephrolithotomy, Flexible Ureterorenoscopy, Shockwave Lithotripsy
- Volunteers
- 90 people
- Sponsor
- Assiut University
Kidney Stone
Reducing Opioid Prescription After Kidney Stone Removal Surgery
The purpose of this study is to implement and assess a standard way of prescribing opioid pain medication following PCNL (a kidney stone removal surgery) to ensure patients are being discharged with an appropriate quantity of…
- Trial name
- NCT05353478
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Renal Calculi
Comparison of Extracorporeal Shock Wave Lithotripsy (ESWL) and Ultra-mini Percutaneous Nephrolithotomy (PCNI), in Renal Stones <20 mm.
There is a dearth of information comparing ultra-mini PNCL with ESWI in Pakistan for kidney stones smaller than 20 mm. Hence the current study was planned with the objective of comparing the outcome of ESWL and ultra-mini PCNL in…
- Trial name
- NCT07610252
- Testing
- Ultra-mini PCNL, Extracorporeal shock wave lithotripsy
- Where
- Pakistan
- Volunteers
- 138 people
- Sponsor
- Muhammad Aamir Latif
Kidney Calculi, Nephrolithotomy, Percutaneous
Bilateral Synchronous Simultaneous Stone Surgery
Advancements in technology and endourological armamentarium provides multiple surgical options for complicated stone patients. To avoid multiple operations and shorten the total operation durations, bilateral synchronous…
- Conditions
- Kidney Calculi, Nephrolithotomy, Percutaneous, Ureteroscopy
- Trial name
- NCT03599297
- Testing
- Bilateral synchronous simultaneous stone surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Urinary Tract Infections, Stent Related Infection
Multicentric Study on Infections of the Urinary Tract After Stent Removal (MINUS-trial).
The MINUS-trial is a multicentric prospective observational study in which consecutive patients, 18 years of age and older who receive a ureteral stent during any endoscopic procedure will be approached to participate.
- Trial name
- MINUS (NCT05329883)
- Testing
- Double-J stent removal
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Urolithiasis, Nephrolithotomy
Exit Strategy After Percutaneous Nephrolithotomy: Large or Small Bore Tube?
Regarding to the distribution of nephrostomy tube (NT) size usage by country. There was a clear distinction between countries that used solely the small bore (SB) NT (Chile and Australia) and those that used solely the large bore…
- Conditions
- Urolithiasis, Nephrolithotomy, Percutaneous Nephrolithotomy (PNL), Nephrostomy Tube (NT)
- Trial name
- NCT04153474
- Testing
- large-bore nephrostomy tube (LBNT), small-bore nephrostomy tube (SBNT)
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Mansoura University
Percutaneous Nephrolithotomy
Lower Thoracic Epidural vs Erector Spinae Block for PNL
compare the efficacy of Lower Thoracic Epidural with Erector spinae plane block (ESPB) for post-operative analgesia after Percutaneous Nephrolithotomy with a hypothesis that both Lower Thoracic Epidural and Erector spinae plane…
- Trial name
- NCT05725083
- Testing
- Lower thoracic epidural, Erector spinae plane block
- Volunteers
- 42 people
- Sponsor
- Assiut University
Postoperative Pain, Percutaneous Nephrolithotomy
The Effectiveness of Quadro İliac Plane Block in Percutaneous Nephrolithotomies
Our aim was to investigate the effect of quadro iliac plane block on postoperative analgesia in patients undergoing percutaneous nephrolithotomy surgery and to determine which areas of the skin this block anesthetizes.
- Trial name
- NCT07203859
- Testing
- Quadro-İliac Plane Block(QİPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Kidney Stone
Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis
The purpose of this study is to compare two variations of the mini-PCNL procedure using either a vacuum-assisted sheath or standard sheath which are both used for the surgical treatment of kidney stones.
- Trial name
- NCT05993546
- Testing
- vacuum assisted sheath, passive suction via conventional sheath
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- The Cleveland Clinic
Stone, Kidney
Clinical Efficacy of Mini-PCNLversus RIRS for the Management of Upper Urinary Tract Calculus (1-2.5 cm)
The goal of this [ type of study:]prospective randomized clinical trial. The main question is to compare the outcomes of mini-percutaneous nephrolithotomy (m-PCNL) and retrograde intrarenal surgery (RIRS) in treating upper…
- Trial name
- NCT06031103
- Testing
- mini-PCNL procedure, RIRS procedure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Percutaneous Nephrolithotomy
Effect of Ondansetron on Spinal-induced Hypotension for Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is the surgical standard for treating large or complex renal stones. The stones are removed by passing a small telescope through the side of the patient directly into the kidney, so the stone…
- Trial name
- NCT04891484
- Testing
- Ondansetron group, Saline group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Mansoura University
Renal Stones
PCNL Versus RIRS for Management of Stones in Solitary Kidney
Few studies compared PCNL and RIRS for stones in solitary kidney. Current guidelines do not provide clear recommendations concerning the management of renal stones in patients with solitary kidney.
- Trial name
- NCT07730892
- Testing
- retrograde intra renal surgery (RIRS), percutaneous nephrolithotomy (PCNL)
- Where
- Egypt
- Volunteers
- 83 people
- Sponsor
- Mansoura University
Kidney Calculi, Urinary Tract Infections
Do Dynamic Urinary Leukocyte and Nitrite Changes Improve Risk Prediction for Infectious Complications Following PCNL?
Background Percutaneous nephrolithotomy (PCNL) is widely recognized as the primary surgical approach for managing sizable and anatomically complex kidney stones., yet postoperative infection-related complications remain common…
- Conditions
- Kidney Calculi, Urinary Tract Infections, Sepsis
- Trial name
- NCT07238673
- Where
- China
- Volunteers
- 346 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Nephrolithotomy, Percutaneous, Kidney Calculi
Total Tubeless Percutaneous Nephrolithotomy Without a Ureteral Catheter
Total tubeless Percutaneous nephrolithotomy (PCNL) is a modified surgical method of PCNL surgery, that is, there is no indwelling nephrostomy tube and double-J tube during PCNL surgery.
- Trial name
- NCT05578807
- Testing
- without reverse ureteral catheter insertion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of University of South China
Renal Calculi
Cost-Effectiveness of Different Treatment Options for Lower Calyceal Stones
The aim of the present study to perform a full cost analysis for the complete clearance of calyceal stones by retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PNL) for the treatment of lower calyceal stones…
- Trial name
- NCT03614247
- Testing
- Retrograde intrarenal surgery, Micro-PNL, Ultra-mini PNL
- Volunteers
- 175 people
- Sponsor
- Ankara Training and Research Hospital
Pediatric Renal Stone
Retrograde Intrarenal Surgery Versus Mini Percutaneous Nephrolithotomy
Pediatric nephrolithiasis accounts for approximately 2-3% of all stone disease cases, with recent reports indicating a rising prevalence of up to 10.6%. This increasing incidence poses a growing public health concern.
- Trial name
- NCT07700251
- Testing
- Retrograde Intrarenal Surgery
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Valley University
Renal Stone, Supine Mini Percutaneous Nephrolithotomy
Retrograde Saline Irrigation During Supine Mini Percutaneous Nephrolithotomy
This minimally invasive surgery allows us to remove kidney stones through tiny incisions and provides patients with quicker and smoother recoveries
- Trial name
- NCT06879990
- Testing
- Retrograde normal saline irrigation, Without Retrograde normal saline irrigation
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kafrelsheikh University
Kidney Calculi Nephrolithiasis Urolithiasis Renal Stone
Which Patinets Benefit More From Percutaneous Nephrolithotomy? A Location-Based Comparative Analysis of PCNL and RIRS for 1-2 cm Renal Stones
This prospective randomized controlled trial aims to compare the clinical efficacy and safety of Percutaneous Nephrolithotomy (PCNL) and Retrograde Intrarenal Surgery (RIRS) for renal stones measuring 10-20 mm.
- Trial name
- NCT07589153
- Testing
- Percutaneous Nephrolithotomy (PCNL), Retrograde Intrarenal Surgery (RIRS)
- Volunteers
- 110 people
- Sponsor
- Kırıkkale University