Clinical trials: Nephrolithotomy Percutaneous
Kidney Stone
Ultrasound-guided Transmuscular Quadratus Lumborum Block for Percutaneous Nephrolithotomy
Patients undergoing percutaneous nephrolithotomy (PNL) suffer from acute postoperative pain, despite a multimodal analgesic regime.
- Trial name
- NCT02818140
- Testing
- Ropivacaine TQL block, Saline TQL block, Ropivacaine
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Nephrolithotomy
Standard Percutaneous Nephrolithotomy Percutaneous Nephrolithotomy (PNL) Versus Tubeless PNL Versus Tubeless Stentless PNL
The purpose of the study is to assess and compare the efficacy and morbidity standard percutaneous nephrolithotomy with tubeless PNL. A total of approximately 60 patients will be enrolled.
- Trial name
- NCT01548196
- Testing
- Standard Percutaneous nephrolithotomy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Stone, Kidney
Single-Shot With Dexmedetomidine Versus Continuous Ultrasound-guided Erector Spinae Plane Block for Postoperative Pain Control After Percutaneous Nephrolithotomy
The current study is designed to assess the efficacy of a single shot ESPB with Dexmedetomidineversus continuous ESPB in perioperative analgesia for PCNL. Both techniques are conducted for patients undergoing PCNL under GA.
- Trial name
- NCT04650737
- Testing
- single shot ESBP with dexmedtomidine, continous ESPB
- Volunteers
- 40 people
- Sponsor
- Cairo University
Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery
Mini Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Pediatric Renal Stones (10-30 mm)
This work aimed to compare the safety and efficacy of retrograde intrarenal surgery using single-use flexible ureteroscopy (FURS) with mini-percutaneous nephrolithotomy (PCNL) in children with renal stones measuring 10-30 mm.
- Conditions
- Mini Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, Pediatric, Renal Stones
- Trial name
- NCT07836192
- Testing
- Mini percutaneous nephrolithotomy, Flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Renal Stones, Postoperative Pain
Comparison of Tubeless Versus Standard Percutaneous Nephrolithotomy (PCNL) for Renal Stones
Percutaneous nephrolithotomy (PCNL) is the surgery usually done to break down kidney stones that are larger than 1.5 cm. Placing a nephrostomy tube after the surgery to drain urine is a common aspect of traditional PCNL.
- Trial name
- TPCNL (NCT07522619)
- Testing
- Standard Percutaneous Nephrolithotomy (Standard PCNL), Tubeless Percutaneous Nephrolithotomy (Tubeless PCNL)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Indus Hospital and Health Network
Kidney Calculi, Nephrolithiasis
Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones.
- Trial name
- NCT07749807
- Testing
- Nebulized Glubran 2-Assisted Tubeless PCNL, Conventional PCNL With Nephrostomy Tube
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Hemodynamic Changes, Surgical Positioning
Surgical Position and Hemodynamics in PCNL
This prospective study aims to evaluate the hemodynamic effects of different surgical positions-supine, lithotomy, and prone-in patients undergoing percutaneous nephrolithotomy (PCNL).
- Conditions
- Hemodynamic Changes, Surgical Positioning, Percutaneous Nephrolithotomy (PCNL)
- Trial name
- NCT07109232
- Testing
- Position the patient
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ataturk University
Percutaneous Nephrolithotomy (PCNL)
Erector Spinae Block vs Conventional Analgesia for Postoperative Analgesia in PCNL
50 adult patients scheduled for percutaneous nephrolithotomy in Sohag university hospitals will be devided in two groups one of them will receive Sonographic guided erector spinae plane block using 20 ml volume of bupivacaine…
- Trial name
- NCT06935006
- Testing
- Sonographic guided Erector spinae plane block, Intravenous opioid
- Volunteers
- 50 people
- Sponsor
- Sohag University
Nephrolithiasis, Postoperative Pain
Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure used to remove large or complex kidney stones. Although effective, dilation of the surgical tract and the placement of a nephrostomy tube cause…
- Conditions
- Nephrolithiasis, Postoperative Pain, Quality of Recovery
- Trial name
- NCT07855068
- Testing
- Ketamine and Dexmedetomidine, Fentanyl
- Volunteers
- 100 people
- Sponsor
- Assiut University
Kidney Calculi, Urinary Tract Infections
Is it Necessary for Patients With a Positive Urine Culture to Achieve a Negative Result After Antimicrobial Treatment Before Undergoing Percutaneous Nephrolithotomy?
Objective: The current European Association of Urology (EAU) guidelines do not provide clear recommendations on whether patients with a positive urine culture(UC) should wait until the culture turns negative following…
- Conditions
- Kidney Calculi, Urinary Tract Infections, Sepsis
- Trial name
- NCT06210425
- Where
- China
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Junhao Zheng
Kidney Stones
FANS-Assisted Mini-PCNL for Complex Renal Stones
This prospective pilot study aims to evaluate the feasibility, safety, and preliminary clinical outcomes of a novel mini-percutaneous nephrolithotomy (mini-PCNL) technique integrating a flexible mini-nephroscope with a flexible…
- Trial name
- FANS-MiniPerc (NCT07332286)
- Testing
- FANS-assisted mini-percutaneous nephrolithotomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Stones
PCNL Versus RIRS for Management of Stones in Solitary Kidney
Few studies compared PCNL and RIRS for stones in solitary kidney. Current guidelines do not provide clear recommendations concerning the management of renal stones in patients with solitary kidney.
- Trial name
- NCT07730892
- Testing
- retrograde intra renal surgery (RIRS), percutaneous nephrolithotomy (PCNL)
- Where
- Egypt
- Volunteers
- 83 people
- Sponsor
- Mansoura University
Kidney Stones, Percutaneous Nephrolithotomy
Paravertebral Versus Caudal Block in Pediatric PCNL
To compare the efficacy of Ultrasound guided thoracic paravertebral block versus ultrasound guided caudal epidural block in pediatric patients undergoing percutaneous nephrolithotomy
- Trial name
- NCT05012215
- Testing
- Paravertebral, Caudal block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Urolithiasis
Radiation Dose of Pediatric Patients During Ureteroscopy
The purpose of this study is to quantify the radiation exposure from diagnostic testing and surgical treatment during routine endourologic procedures for symptomatic urolithiasis.
- Trial name
- NCT02895711
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Pittsburgh
Renal Stone
ROBOTIC PYELOLITHIOTOMY VERSUS PERCUTANEOUS NEPHROLITHOTOMY (PCNL).
Prospectively randomized study in patients with renal pelvic stones who are candidate to standard PCNL procedure. One to one, controlled clinical trial.
- Trial name
- NCT03046888
- Testing
- Robot assisted pyelolithotomy
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital
Stone;Renal, Stone, Urinary
Comparison Between Two Methods for Renal Stone Treatment Mini Percutaneous Nephrolithotomy and Flexible Ureteroscopy With Suction Sheath
This study aims to compare the efficacy and safety of two modern, minimally invasive surgical techniques for the removal of kidney stones: Mini-Percutaneous Nephrolithotomy (Mini-PCNL) and Flexible Ureteroscopy (FURS) with…
- Conditions
- Stone;Renal, Stone, Urinary, Stone, Kidney, Stone Clearance
- Trial name
- mini-PCNL/FANS (NCT07306819)
- Testing
- mini-percutaneous nephrolithotomy, Flexible Uerteroscopy with Tip-Bendable Suction Sheath
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Percutaneous Nephrolithotomy (PCNL)
Intrathecal Fentanyl and Dexmedetomidine Added to Bupivacaine for Subarachnoid Anaesthesia for Percutaneous Nephrolithotomy
Regular bupivacaine dosages are linked to considerable sympathetic block, as well as persistent and severe sensory and motor block, which may not be desired for certain individuals.
- Trial name
- NCT06957301
- Testing
- Intrathecal Fentanyl Group (F), intrathecal dexmedetomidine group(D)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Nephrolithiasis, Urinary Tract Infections
A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
When patients are going to have surgery to remove large kidney stones (percutaneous nephrolithotomy [PCNL]), it is not clear whether the patients benefit from a course of prophylactic preoperative oral antibiotics; currently both…
- Trial name
- NCT02384200
- Testing
- nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin
- Where
- 8 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Renal Calculi
The Influence of SMP on Renal Pelvic Pressure In Vivo
Percutaneous nephrolithotomy (PCNL) is a well-established treatment modality for renal stones. It offers a high stone free rates and less invasive than open surgery.
- Trial name
- NCT02760134
- Testing
- Super-Mini Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University