Clinical trials: Nerve Block/Methods, open to volunteers
Pain Management, Anesthesia , Analgesia
Comparison Between External Oblique Intercostal Plane Block and Rectus Sheath Block Combined With Transversus Abdominis Plane Block
Effective perioperative pain management remains a cornerstone in enhancing recovery and improving patient outcomes in laparoscopic cholecystectomy.
- Conditions
- Pain Management, Anesthesia , Analgesia, Nerve Block
- Trial name
- NCT07384000
- Testing
- External intercostal plane puncture, control group (nalbuphine), the single-puncture technique of (rectus sheath block) combined with (Transversus abdominis plane block)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Post Operative Analgesia, Total Knee Arthroplasty
Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques
Postoperative pain following total knee arthroplasty (TKA) is a significant clinical problem that delays early mobilization, reduces patient satisfaction, and increases analgesic requirements.
- Trial name
- NCT07242170
- Testing
- Adductor canal block, BiFeS Block (Biceps Femoris Short Head Block), IPACK block
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Erzincan University
Loco-regional Anesthesia
Comparison of Loco-regional Analgesic Techniques in Patients Undergoing Video Assisted Thoracoscopic Surgery (VATS)
This study aims to compare two loco-regional analgesic techniques: 1. Intercostal nerve block: Performed by the surgeon intraoperatively before final lung re-expansion, involving the administration of 20 mL of 0.5%…
- Trial name
- PRoGEVATS (NCT07102173)
- Testing
- Intercostal nerve block, Ultrasound-guided ESPB
- Volunteers
- 72 people
- Sponsor
- ASST Sette Laghi
Augmented Reality, Virtual Reality
Augmented Reality/Virtual Reality (AR/VR) for Ultrasound-guided Medical Procedures
The study seeks to assess the efficacy of incorporating augmented reality (AR) or virtual reality (VR) technology into ultrasound-guided medical procedures such as regional anesthesia and line placement.
- Trial name
- NCT06550193
- Testing
- Ultrasound-guided procedure using AR/VR technology
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Anesthesia, Analgesia
Near Remote Method to Guide Performance of Regional Anesthesia
Ultrasound-guided regional anesthesia/analgesia techniques (or simply, 'regional blocks') have gained popularity as they can reduce, and sometimes even eliminate, the need for opiate analgesics (and, consequently, their side…
- Conditions
- Anesthesia, Analgesia, Nerve Block, Delivery of Healthcare
- Trial name
- NCT05968261
- Testing
- Real time 'near remote' guidance of regional blocks
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Glenio Mizubuti (MD, PhD)
Shoulder Arthroscopy, Interscalene Nerve Block
Effect of Anesthesia Technique on Surgical View in Shoulder Arthroscopy
This prospective observational study evaluates the effect of the anesthesia method (general anesthesia versus regional anesthesia [interscalene nerve block/superficial cervical block] with sedation) on the operating clarity of…
- Conditions
- Shoulder Arthroscopy, Interscalene Nerve Block, Surgical View Quality, Surgeon Satisfaction
- Trial name
- NCT07343414
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Amasya University
Postoperative Pain, Delirium - Postoperative
Analgesia Methods and Early Mobilization in Geriatric ICU Patients After Major Surgery
This study looks at how different pain-control methods affect how quickly older adults get out of bed and start moving again after major surgery.
- Conditions
- Postoperative Pain, Delirium - Postoperative, Frailty, Postoperative Care in Geriatric Intensive Care Patients
- Trial name
- NCT07709975
- Testing
- Systemic Opioid Analgesia (± Multimodal), Epidural Analgesia, Peripheral Nerve Block (± Multimodal)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Caries, Dental, Local Anesthesia
Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients
This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children…
- Conditions
- Caries, Dental, Local Anesthesia, Inferior Alveolar Nerve Block, Dental Anxiety
- Trial name
- NCT07133919
- Testing
- AI-Assisted Child-Friendly Communication, Traditional Behavior Management Techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Arthroplasty Replacement, Knee, Anesthesia Conduction
Migration Rate for Continuous Adductor Canal Block Catheters After Primary Total Knee Arthroplasty Surgery: a Comparison Between Two Insertion Techniques
Continuous adductor canal block (CACB) is becoming increasingly popular for providing postoperative analgesia following knee arthroplasties.
- Trial name
- ISAFExOOPS (NCT07681622)
- Testing
- ISAFE technique for adductor canal catheter insertion, OOPS technique
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Pulmonary Dysfunction, Median Sternotomy Recovery
FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy
Background and Rationale: Open-heart surgery via a median sternotomy is associated with severe acute postoperative pain. This pain can impair a patient's ability to take deep breaths and cough effectively which increases the risk…
- Conditions
- Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
- Trial name
- FROST-STERN (NCT07637370)
- Testing
- Intercostal Nerve Cryoablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Arthroplasty, Replacement, Knee, Pain, Postoperative
BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia
The Biceps Femoris Short Head (BiFeS) block is a new fascial plane block technique targeting the sensory innervation of the posterolateral capsule of the knee while preserving motor function.
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Anesthesia, Regional
- Trial name
- NCT07360392
- Testing
- Biceps Femoris Short Head Block (BiFeS), Infiltration Between The Popliteal Artery and The Capsule of The Knee, Adductor Canal Block
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Amasya University
Analgesia Assessment, Above Knee Amputation
The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .
The aim of this study is to compare the analgesic efficacy and safety of dexmedetomidine versus fentanyl as adjuvants to bupivacaine in ultrasound-guided combined supra-inguinal fascia iliaca and proximal sciatic nerve blocks…
- Conditions
- Analgesia Assessment, Above Knee Amputation, Fentanyl vs Dexmedetomidine
- Trial name
- NCT07640516
- Testing
- Dexmedetomidine, Fentanyl (as Citrate)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Kasr El Aini Hospital
Cancer, Malignant Tumors, Abdominal Cancer
Neurolytic Block Techniques In Abdominal Visceral Cancer Pain
The neurolytic blocks of sympathetic chains are commonly used for the treatment of cancer-related pain. This study aims to compare celiac plexus neurolysis and splanchnic nerve neurolysis for the treatment of abdominal visceral…
- Conditions
- Cancer, Malignant Tumors, Abdominal Cancer, Cancer Pain, Visceral Pain
- Trial name
- CONCERN (NCT06978673)
- Testing
- Splanchnic nerve neurolysis - 5 ml of absolute alcohol (100%), Celiac Plexus Neurolysis - 5 ml of absolute alcohol (100%)
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Knee Osteoarthritis, Total Knee Arthroplasty
Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty
This study aims to compare the analgesic efficacy of surgeon-performed intraoperative adductor canal block (ACB) and ultrasound-guided anesthesiologist-performed ACB in patients undergoing bilateral total knee arthroplasty (TKA).
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Postoperative Pain, Peripheral Nerve Block
- Trial name
- NCT07506629
- Testing
- Surgeon-Performed Adductor Canal Block, Ultrasound-Guided Adductor Canal Block
- Volunteers
- 48 people
- Sponsor
- Yonsei University
Perineal Laceration, Tear, or Rupture During Delivery
Study on Fewer Tears (SOFT) - The Effect of Local Anesthesia on the Incidence of Perineal Tears in the First Vaginal Birth
The SOFT study investigates whether local anaesthesia during the second stage of labor decreases the incidence of perineal tears, including sphincter injuries, in women with their first vaginal birth (non-instrumental).
- Trial name
- SOFT (NCT07499752)
- Testing
- Perineal protection techniques
- Where
- Sweden
- Volunteers
- 1,350 people
- Sponsor
- Karolinska Institutet
Nerve Block, Neuromuscular Blockade
LIA vs. LIA + ACB-iPACK Block for Total Knee Arthroplasty
LIA is the mainstay of postoperative analgesia in patients having knee arthroplasty. The combination of ACB-iPACK blocks has also been proposed as an effective analgesic modality for total knee arthroplasty.
- Trial name
- NCT04808947
- Testing
- Local infiltration analgesia, Ultrasound-guided adductor canal block
- Volunteers
- 60 people
- Sponsor
- Women's College Hospital
Wrist Fracture
Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study)
The purpose of this study is to compare different types of local anesthesia-a supracondylar radial nerve block, a hematoma block, or a combination of the two-for reducing pain in people with a broken wrist (distal radius…
- Trial name
- NCT07268547
- Testing
- Supracondylar radial nerve block, Hematoma block, Combination of blocks
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Sarasota Memorial Health Care System
Knee Arthropathy, Hip Injuries
A Study to Evaluate Virtual Reality As Adjunct to Anesthesia During Orthopedic Surgery
The purpose of this study is to obtain feedback from patients and orthopedic surgeons who agree to use virtual reality (VR ) as an adjunct to standard of care in orthopedic cases under regional or central neuraxial nerve block.
- Trial name
- NCT05112302
- Testing
- Virtual reality
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Hemorrhoids, Postoperative Pain
Pudendal Nerve Block Techniques for Pain Control After Hemorrhoidectomy
Hemorrhoidectomy is frequently associated with severe postoperative pain despite multimodal analgesia. Ultrasound-guided pudendal nerve block has become an effective regional analgesic technique, but it remains unknown whether…
- Trial name
- PINPOINT (NCT07813338)
- Testing
- Transgluteal Pudendal Nerve Block, Transperineal pudendal nerve block
- Volunteers
- 140 people
- Sponsor
- Vinmec Healthcare System