Clinical trials: Nerve Block Assessment
Dento Facial Dysmorphism
Evaluation of Maxillary and Mandibulary Nerve Blocks on Morphine Consumption
Background and Objectives: Double-jaw surgery is one of the most painful oral surgery, requiring multimodal analgesia including controlled morphine pump and its secondary effects.
- Trial name
- NCT03299998
- Testing
- Maxillary and mandibular blocks, General anesthesia
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College
Hypertensive Leg Ulcer
To Assess Analgesia Provided by Continuous Sciatic Nerve Block in Patients With Hypertensive Leg Ulcer
Hypertensive leg ulcer, also called Martorell ulcer, represents 1 to 15% of leg ulcers in hospital. These ulcers are painful, long to heal, and hospitalization is sometimes necessary for analgesia and debridement of necrotic…
- Trial name
- ANGIOCATH (NCT01964911)
- Testing
- Ropivacaïne
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Nantes University Hospital
AI (Artificial Intelligence), Ultrasound-Guided Nerve Blocks
AI-Assisted Ultrasound-Guided Nerve Block: Model Development and Performance Assessment
This study intends to have experts with over 10 years of experience in ultrasound-guided regional anesthesia acquire 1,000 target images.
- Trial name
- AI (NCT07171502)
- Testing
- AI Annotation, manual annotation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Post-operative Pain, Anesthesia, Local
Evaluation of the Analgesic Benefit of Adding the Blocks of the Intermediate and Medial Femoral Cutaneous Nerves in Addition to the Femoral Triangle Block for Postoperative Analgesia After a Knee Replacement Surgery
Total knee replacement surgery can be associated with a significant postoperative pain burden and an inability to mobilize adequately, which can lead to the failure of the ambulatory course.
- Trial name
- NCT06038851
- Testing
- Para-Sartorial Compartments (PACS) Block, Femoral Triangle Block (FTB), Infiltration between popliteal artery and capsule of the knee (IPACK) block
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Diaphragm Paralysis
The Effect of Interscalene Peripheral Nerve Block With 0.25% Bupivacaine vs 0.125% Bupivacaine on Lung Function
Peripheral nerve blocks are used to provide post-operative pain relief. Nerve blocks in the neck, in the interscalene area, provide pain relief after shoulder surgery but can cause temporary weakness or paralysis of the…
- Trial name
- NCT01429584
- Testing
- interscalene nerve block with 0.25% bupivacaine, interscalene block with 0.125% bupivacaine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Foot Injury, Ankle Injury
Ideal Anatomic Location for Saphenous Nerve Blocks: A Prospective Clinical Evaluation
This research is being done to compare two different saphenous nerve block locations and will help to determine which site best maintains knee strength and pain control.
- Trial name
- NCT02645097
- Testing
- Saphenous Nerve Block
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Paul J. Juliano, M.D.
Breast Cancer, Breast Cancer Female
Study of Nerve Block Pain Management in Patients Undergoing a Double Mastectomy With Immediate Reconstruction
The purpose of this study is to determine if the injection site or sites used for administering pain medication (nerve blocks) before a double mastectomy with immediate reconstruction with tissue expanders reduce the need for…
- Trial name
- NCT04016376
- Testing
- PVB Protocol, PECS-1, Serratus
- Where
- United States
- Volunteers
- 1,507 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Postoperative Pain Following Knee Arthroplasty
Efficacy of Peripheral Nerve Blocks in Total Knee Arthroplasty
In total knee arthroplasty, the effectiveness of some peripheral nerve blocks in postoperative pain control has been investigated, with conflicting results reported.
- Trial name
- NCT07040709
- Testing
- Opioid Analgesic (tramadol hydrochloride), Prophylactic analgesia (intravenous paracetamol), Rescue analgesia (intramuscular diclofenac sodium)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Tokat Gaziosmanpasa University
Cleft Palate
Suprazygomatic Block in Cleft Palate Surgery in Children
Cleft palate (CP) is a common congenital malformation, with an incidence ranging from 0.1 to 1.1 per 1000 births depending on the population group (liau et al, 2010).
- Trial name
- NCT03412474
- Testing
- Bupivacaine, Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sciatic Nerve, Adductor Canal Syndrome
Evaluation of Local Anesthetic Diffusion to the Sciatic Nerve During Adductor Canal Block
Adductor canal block is an effective analgesic technique for major knee surgery. However, the saphenous nerve block is not sufficient to explain this block's efficiency.
- Trial name
- DiffuCAdd (NCT07301476)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Total Ankle Arthroplasty, Postsurgical Analgesia
Efficacy of EXPAREL vs. Bupivacaine
The goal of this clinical study is to learn about pain management strategies in subjects undergoing total ankle replacement. arthroplasty surgery The primary objective is to compare the magnitude of the analgesic effect following…
- Trial name
- NCT07212114
- Testing
- EXPAREL, 0.25% bupivacaine (HCl): 50 ml, 0.25% bupivacaine (HCl): 30 ml
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Emory University
Postoperative Pain
Modified Pectoral Nerves Block Versus Serratus Plane Block in Major Breast Cancer Surgery
The purpose of this study is to compare the analgesic profile of modified pectoral nerves block and serratus plane block in patients undergoing mastectomy.
- Trial name
- NCT02946294
- Testing
- Bupivacaine 0.25% with epinephrine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Acupuncture, Tumor, Brain
Evaluation of Acupuncture Effects for Complications After Surgery of Cerebellopontine Angle Tumor in Skull Base
Skull base tumors are a type of tumor that grow in the area of several skulls behind the cranial cavity. The incidence rate is 2 to 18 per 100,000 people per year; males and females are likely to have a proportional difference in…
- Conditions
- Acupuncture, Tumor, Brain, Skull Base Tumor, Cerebellopontine Angle Tumor
- Trial name
- NCT04249921
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Acute Pain, Post Operative Analgesia
Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy
Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid…
- Conditions
- Acute Pain, Post Operative Analgesia, Post Operative Pain, Acute, Breast Cancer
- Trial name
- PECS-TPVB (NCT07738770)
- Testing
- Combined PECS II and Superficial PIP Block, Thoracic paravertebral block (TPVB)
- Where
- Indonesia
- Volunteers
- 72 people
- Sponsor
- Dharmais National Cancer Center Hospital
Pulpitis - Irreversible
Evaluation of the Effect of Adding Dexamethasone to 2% Lidocaine
This randomized, double-blind clinical trial aimed at the evaluation of the effect of adding dexamethasone to 2% lidocaine, given as inferior alveolar nerve block in the endodontic management of symptomatic irreversible pulpitis.
- Trial name
- NCT05361291
- Testing
- Lidocaine Hydrochloride
- Where
- India
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Surgery of Arthroscopic Anterior Cruciate Ligament Repair
Assessment of Adductor Canal Blockade in Anterior Cruciate Ligament Surgery
Assessment of sensory and motor blockade of adductor canal blockade performed for anterior cruciate ligament repair in comparison with femoral nerve blockade.
- Trial name
- ACB (NCT02419261)
- Testing
- Analgesic nerve blockade (Ropivacaine), Arthroscopic surgical repair of the anterior cruciate ligament
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University of Liege
Cardiac Implantable Electronic Device, Nerve Block
PECs for Implantable Cardiac Electronic Device Insertion
The aim of this study is to evaluate the feasibility of the Pectoralis Nerve (PECS) block for CIED insertion.
- Conditions
- Cardiac Implantable Electronic Device, Nerve Block, Anesthesia, Analgesia
- Trial name
- NCT05528627
- Testing
- Pectoral Nerve (PECs) block
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Antalya Training and Research Hospital
Melanoma
Pilot Study of the Safety/Efficacy of Combination Checkpoint Blockade + External Beam Radiotherapy in Stage IV Melanoma
This is an ongoing, Phase 1, open-label, multicenter, pilot study of the checkpoint antibodies ipilimumab and nivolumab in combination with radiotherapy (RT) in 18 subjects with unresectable Stage IV melanoma.
- Trial name
- NCT02659540
- Testing
- Nivolumab, Ipilimumab, Radiotherapy
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Ludwig Institute for Cancer Research
Local Anesthesia
Buffered Anesthetic Solution in the Treatment of Mandibular Primary Molars
In a prospective, randomized clinical trial, triple-blind, split-mouth study, 40 children aged between 7 to 10 with bilateral mandibular primary molars were diagnosed with pulpitis.
- Trial name
- NCT05793905
- Testing
- Buffered lidocaine in inferior alveolar nerve block injection, lidocaine 2% in inferior alveolar nerve block injection
- Where
- Syria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Damascus University