Clinical trials: Nerve Block Duration
Rheumatoid Arthritis, Osteoarthritis
Low Dose Dexamethasone in Supraclavicular Blocks
Brachial plexus nerve blocks provide superior analgesia over opioids while avoiding unwanted side effects. Single shot blocks with local anesthetic alone usually do not last the duration of the acute post-surgical pain period.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Nerve Entrapment, Ligament Injury
- Trial name
- NCT02666443
- Testing
- Control intervention (no dexamethasone), Peri-neural Dexamethasone 1 mg, Intravenous Dexamethasone 1 mg
- Where
- Canada
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Postoperative Pain
The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability
The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve…
- Trial name
- NCT02829697
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Healthy
Perineural Dexmedetomidine for Ulnar Nerve Block.
The aim of this trial is to investigate if dexmedetomidine prolongs the duration of an ulnar nerve block. By using healthy volunteers the investigators can perform bilateral ulnar nerve blocks and thereby control for a systemic…
- Trial name
- NCT03222323
- Testing
- Dexmedetomidine perineurally, Ropivacaine 5mg/ml, Ropivacaine 7.5mg/ml
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Healthy
Does Perineural Dexmedetomidine Prolong Duration of a Nerve Block?
Brief Summary: The aim of this trial is to investigate if dexmedetomidine prolongs the duration of an adductor canal block. By using healthy volunteers the investigators can perform a bilateral adductor canal block and thereby…
- Trial name
- NCT02488473
- Testing
- Dexmedetomidine, Ropivacaine, Isotonic Saline
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Other Acute Postoperative Pain, Pain, Postoperative
Effects of Local Anaesthetic Infusion Rates on Nerve Block Duration
This trial is a part of the project: 'A novel technique for reliable, precise and safe postoperative pain management' (project no. 65-2014-3).
- Conditions
- Other Acute Postoperative Pain, Pain, Postoperative, Anaesthesia
- Trial name
- NCT02801799
- Testing
- Varying infusion rates of Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Analgesia, Pain, Acute
Duration of Analgesia With Dexmedetomidine and Ropivacaine in Brachial Plexus Block
This is a prospective, randomized, double blind study of adding dexmedetomidine to ropivacaine for Brachial plexus block and assessing the analgesia with VAS pain scales(0-10), Satisfaction scale by VAS scale(0-10) and time to…
- Conditions
- Analgesia, Pain, Acute, Peripheral Nerve Block
- Trial name
- NCT03385967
- Testing
- Dexmedetomidine, ropivacaine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Anesthesia, Analgesia
Near Remote Method to Guide Performance of Regional Anesthesia
Ultrasound-guided regional anesthesia/analgesia techniques (or simply, 'regional blocks') have gained popularity as they can reduce, and sometimes even eliminate, the need for opiate analgesics (and, consequently, their side…
- Conditions
- Anesthesia, Analgesia, Nerve Block, Delivery of Healthcare
- Trial name
- NCT05968261
- Testing
- Real time 'near remote' guidance of regional blocks
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Glenio Mizubuti (MD, PhD)
Shoulder Pain, Injury of Shoulder Region
Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
The purpose of this study is to determine the Finger Blood Glucose (sugar) when dexamethasone is added to a local anesthetic for a shoulder nerve block procedure.
- Conditions
- Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder, Disorder of Rotator Cuff
- Trial name
- NCT01538459
- Testing
- Dexamethasone, Bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lifespan
Anesthesia, Regional
Intra-individual Reproducibility in Nerve Block Duration
An interventional randomized controlled crossover trial, to illuminate if durations in nerve block durations are predictable within the same subject.
- Trial name
- NCT03310047
- Testing
- Infusion, Lidocaine, 0.5%, 5 mL, Infusion, Lidocaine, 0.5%, 10 mL
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Anesthesia, Local
Analgesia Duration of Dexamethasone, Buprenorphine, or Clonidine With Ropivacaine for Interscalene Nerve Block
This is a prospective randomized controlled triple-masked study looking at the duration of nerve block analgesia when using the listed adjuvants (dexamethasone, buprenorphine and clonidine) plus ropivacaine versus plain…
- Trial name
- NCT03117140
- Testing
- Ropivacaine 0.75%, Ropivacaine 0.75% + 300 mcg Buprenorphine, Ropivacaine 0.75% + 75 mcg clonidine
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Melinda Seering
Peripheral Nerve Block
Local Anesthetic Concentration and Nerve Block Duration
Background: Local anesthetic (LA) concentration and nerve block duration is sparsely described in a heterogenic study mass. Aim: To investigate the effect of LA concentration on peripheral nerve block duration in healthy…
- Trial name
- NCT03326609
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Nerve Block, Opioid Tolerance
Duration of Peripheral Nerve Blocks in Opioid Tolerant Individuals - A Volunteer Blinded Matched Case-control Study
Do peripheral nerve blocks work shorter if you are on opioids? Background: Peripheral nerve blocks effectively alleviate postoperative pain.
- Trial name
- OPITOBLOK (NCT06488768)
- Testing
- Radial nerve block
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charlotte Runge
Pain
Bupivacaine Digital Blocks: How Long is the Pain Relief and Temperature Elevation?
No one knows how long bupivacaine finger blocks last. Many use bupivacaine with and without epinephrine, but no one knows how the epinephrine affects the duration of the block.
- Trial name
- NCT01698593
- Testing
- Bupivacaine 0.5%, Bupivacaine 0.5% + Epinephrine (1:200,000)
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Lalonde, Donald H., M.D.
Healthy
The Effect of Different Doses (Mass) of Local Anesthetic on Duration of Adductor Canal Block in Healthy Volunteers - Part 2
To investigate whether increased dose of local anesthetic (lidocaine) increases duration of peripheral nerve block (adductor canal block) and to develop a model for assessing duration of peripheral nerve blockades.
- Trial name
- NCT02172729
- Testing
- Adductor canal block with 20 ml lidocaine, single bolus
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Postoperative, Anesthesia, Local
Comparison of Ultrasound-guided Brachial Plexus Blocks and Selective Distal Blocks in Terms of Anesthesia
Ultrasound-guided brachial plexus blocks (infraclavicular, axillary) can be applied as the main anesthetic method in hand and wrist surgeries, as well as single or combination block applications of the median, radial and ulnar…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Patient Satisfaction
- Trial name
- NCT05656625
- Testing
- descriptive
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Samsun University
Anesthesia, Local
Does Perineural Dexamethasone Increase the Duration of an Ulnar Nerve Block When Controlling for Systemic Effects?
Investigators will assess if perineural dexamethasone can increase the duration of an ulnar nerve block when controlling for systemic effects in healthy volunteers.
- Trial name
- NCT04817982
- Testing
- Perineural dexamethasone, Lidocaine, Systemic dexamethasone
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Pain
Dexamethasone With TAP Block Increasing the Duration of the Peripheral Nerve Block in Caesarian Section
Nowadays Cesarean sections became the most popular surgery worldwide with the consumption of the hospital resources and the continuous need to decrease the costs, work load and medical stuff engagement.
- Trial name
- NCT02440880
- Testing
- Dexamethasone in addition to TAP block in dose of 4 mg, Dexamethasone in combination with TAP block in dose of 8 mg, Dexamethasone intravenous 4mg+ TAP block
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Onset and Duration of a Digital Nerve Block
Determination of the Duration of Action of a Lidocaine and a Bupivacaine Digital Nerve Block in Human Volunteers
The duration of the autonomic (sympathetic) block will last longer than the sensory block. The duration of the increased perfusion index will last longer than either the sympathetic or sensory block.
- Trial name
- NCT01508832
- Testing
- Lidocaine Digital Nerve Block, Bupivacaine Digital Block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco