Clinical trials: Nerve Blocks
Failed Mechanical Induction
Efficacy of Ketorolac Buccal Infiltration on Success Rate of Inferior Alveolar Nerve Block
The aim of this study was to determine whether combining an intraoral injection of a non steroidal anti-inflammatory drug (Ketorolac), in association with conventional inferior alveolar nerve block, would improve the success rate…
- Trial name
- NCT02536430
- Testing
- Ketorolac Tromethamine
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nahid Mohammadzadeh Akhlaghi
Pulpitis - Irreversible
SCN9A Gene Expression and Inflammatory Cytokines
Voltage-gated sodium channels, especially Nav1.7 encoded by the SCN9A gene, are key regulators of nociceptive transmission. Upregulation of SCN9A has been associated with increased neuronal excitability and heightened pain…
- Trial name
- Gene Expressio (NCT07532200)
- Testing
- Inferior Alveolar Nerve Block
- Where
- India
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Migraine
A Research Study of Greater Occipital Nerve Block as a Treatment for Acute Migraine Attacks
Several observational studies have shown improvement in episodic migraine with the use of greater occipital nerve block as an acute therapy, and a recent placebo controlled trial did not show a decrease in frequency of episodic…
- Trial name
- NCT03159000
- Testing
- Saline, lidocaine/bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Saphenous Nerve Block
Saphenous Nerve Block for Foot and Ankle Surgery
Patients undergoing foot and ankle surgery have the option of having a nerve block administered by their Anesthesiologist. The nerve block numbs the foot and results in less post-operative nausea and vomiting, and better pain…
- Trial name
- NCT02382744
- Testing
- Ultrasound Guidance, Ultrasound guidance + nerve stimulation
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postoperative Pain, Nerve Block
Pain-relieving Methods After Laparoscopic Hemicolectomy
Effects of Transabdominal Plain Block and Quadratus Lumborum Block After Laparoscopic Hemicolectomy. The pain relief, bowel function and discharge.
- Trial name
- NCT05273281
- Testing
- Transabdominal plane block, Quadratus lumborum block
- Where
- Finland
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Onset and Duration of a Digital Nerve Block
Determination of the Duration of Action of a Lidocaine and a Bupivacaine Digital Nerve Block in Human Volunteers
The duration of the autonomic (sympathetic) block will last longer than the sensory block. The duration of the increased perfusion index will last longer than either the sympathetic or sensory block.
- Trial name
- NCT01508832
- Testing
- Lidocaine Digital Nerve Block, Bupivacaine Digital Block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Upper Limb Surgery
Ultrasound-guided Versus Blind Technique in Medial Brachial Cutaneous Nerve and Intercostobrachial Nerve Blocks
The axillary brachial plexus block is a technique of locoregional anesthesia indicated in the distal upper limb surgery : hand, forearm, the lower third of the arm including the elbow.
- Trial name
- ECHO_NCMB (NCT02940847)
- Testing
- medial brachial cutaneous nerve block and intercostobrachial nerve block with blind technique, medial brachial cutaneous nerve block and intercostobrachial nerve block with ultrasound-guided technique
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Breast Cancer, Mastectomy
Preoperative Regional Nerve Block for Acute and Chronic Post-Operative Pain Following Mastectomy
The purpose of this study is to see if pre-operative regional nerve blocks compared to a placebo nerve block can decrease chronic post mastectomy pain, immediate postoperative pain and postoperative narcotic consumption.
- Conditions
- Breast Cancer, Mastectomy, Anesthesia, Local, Narcotic Use
- Trial name
- RELIEF (NCT04019834)
- Testing
- regional nerve block with local anesthesia of bupivacaine with steroid
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pediatric Anesthesia, Local Anesthesia
Local Anesthesia With Needle-free Injection System
The purpose of this study was to compare the pain during needle insertion and injection in mandibular molars anesthetized with either traditional syringe (control) or Comfort in System (experimental).
- Trial name
- anesthesia (NCT04028271)
- Testing
- Comfort-in injection system, conventional injection with dental needle
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sinem yildirim
Healthy
The Impact of Local Anesthetic Dilution on Possible Blinding for Nerve Blocks
This study aims to determine the appropriate dosage of a placebo anesthetic to enable future placebo-controlled studies that can more accurately examine the effects of nerve blocks.
- Trial name
- NCT06668116
- Testing
- Ropivacaine 0,1%
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Arthropathy of Knee
Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Peripheral nerve blocks catheters of the femoral nerve have long been used for perioperative analgesia in total knee arthroplasty (TKA). These blocks provide effective analgesia and patient satisfaction for surgical pain relief.
- Trial name
- NCT03133481
- Testing
- Adductor Canal Nerve Block, Femoral Nerve Block
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Electrical Stimulation, Neuromodulation
Percutaneous High Frequency Alternating Current Stimulation in Healthy Volunteers
High-frequency alternating currents of greater than 1 kHz applied on peripheral nerves has been used in animal studies to produce a motor nerve block.
- Trial name
- NCT04346719
- Testing
- 10 kHz stimulation (Myomed 932, Enraf-Nonius), 20 kHz stimulation (Myomed 932, Enraf-Nonius)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Brachial Plexus Block
The Musculocutaneous Nerve in a High Resolution MRI
The investigators have made a favourable experience with the in 2006 published transarterial triple injection method [4]. This classic method combines the block effect of an axillary catheter injection (median nerve position)…
- Trial name
- NCT02305875
- Testing
- MCN scoring
- Where
- Norway
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Diakonhjemmet Hospital
Shoulder Disease
Catheter Over Needle (CON) vs Catheter Through Needle (CTN).
This is a randomized clinical trial with the objective of comparing the time of insertion of two types of perineural catheters in shoulder surgery.
- Trial name
- CONvsCTN (NCT05960799)
- Testing
- CON - Contiplex C™ (CC), CTN - Contiplex
- Where
- Chile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Pain Management, Anesthesia , Analgesia
Comparison Between External Oblique Intercostal Plane Block and Rectus Sheath Block Combined With Transversus Abdominis Plane Block
Effective perioperative pain management remains a cornerstone in enhancing recovery and improving patient outcomes in laparoscopic cholecystectomy.
- Conditions
- Pain Management, Anesthesia , Analgesia, Nerve Block
- Trial name
- NCT07384000
- Testing
- External intercostal plane puncture, control group (nalbuphine), the single-puncture technique of (rectus sheath block) combined with (Transversus abdominis plane block)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Hip Fractures
Comparison of Pericapsular Nerve Group Block With Suprainguinal Fascia Compartment Block in Hip Fractures
Ultrasound-guided Supra-inguinal Fascia Iliaca compartment Block (SIFCB) and Pericapsular Nerve Group Block (PENG) are increasingly being used for postoperative analgesia for hip surgery.
- Trial name
- NCT06169462
- Testing
- PENG block, PENG block+ SIFCB
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Strabismus
Effect of Neuromuscular Blockade on the Oculomotor by Not Squinting Child
Strabismus is a common condition (4-6% of the population) . The screening and treatment is a public health issue. Indeed, beyond the disfigurement, this disease is very supplier of amblyopia which is definitive if it is not…
- Trial name
- STRABO (NCT02360969)
- Testing
- Examination of the eye
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Meralgia Paresthetica
Comparing Ways to Freeze the Nerve That Provides Thigh Sensation
Background The sensation on the outside of portion of our thighs is provided by a nerve called the lateral femoral cutaneous nerve (LFCN).
- Trial name
- NCT02577510
- Testing
- Nerve Injection- Nerve Stimulator, Nerve Injection - Ultrasound
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Canadian Forces Health Services Centre Ottawa
Pain
A Novel Concept for Continuous Peripheral Nerve Block - Sciatic Nerve
To investigate the function of a novel catheter for continuous peripheral nerve blocks in the popliteal nerve: Two key issues are investigated 1) Successful primary placement and function of the catheter for continuous peripheral…
- Trial name
- NCT02456597
- Testing
- lidocainhydrochlorid, Isotonic Saline
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kai Henrik Wiborg Lange