Clinical trials: Nerve Compression Syndromes
Carpal Tunnel Syndrome (CTS)
Open vs. Ultrasound-Guided Carpal Tunnel Release
Carpal Tunnel Syndrome (CTS) is the most prevalent entrapment neuropathy. Open Surgical Carpal Tunnel Release (OSCTR) remains the gold standard, while minimally invasive Ultrasound-Guided Carpal Tunnel Release (USGCTR) offers…
- Trial name
- NCT07814547
- Testing
- Open Surgical Carpal Tunnel Release (OSCTR), Ultrasound-Guided Carpal Tunnel Release (USGCTR)
- Where
- 2 sites in Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AUVA General Trauma Hospital Salzburg
Carpal Tunnel Syndrome
Treatment of Carpal Tunnel Syndrome With Dynamic Splinting
The Purpose of this study is to examine the effect of using the Carpal Tunnel Dynasplint® System on patients diagnosed with CTS in a randomized, controlled, cross-over study.
- Trial name
- NCT00558116
- Testing
- Dynamic splinting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Advanced Centers for Orthopaedic Surgery and Sports Medicine
Carpal Tunnel Syndrome, Carpal Tunnel Syndrome Bilateral
Comparison of Interventions in Patients With Carpal Tunnel Syndrome
This study aims to compare two types of intervention (stretching and myofascial manipulation) in the treatment of individuals with bilateral idiopathic carpal tunnel syndrome.
- Trial name
- NCT04347746
- Testing
- stretching physiotherapy, Myofascial therapy
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
Carpal Tunnel Syndrome
Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome
This study applies the regenerative properties of autologous fat transfer to treat mild to moderate carpal tunnel syndrome in comparison to the current standard of care, corticosteroid treatment.
- Trial name
- NCT03722303
- Testing
- Fat Injection, Steroid Injection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anterior Cutaneous Nerve Entrapment Syndrome
Effect of Abdominal Wall Injections on Abdominal Pain
This is a prospective cohort study of outpatient adults with chronic abdominal wall pain receiving abdominal wall injections, as part of their usual care, with lidocaine.
- Trial name
- NCT06121466
- Testing
- Abdominal wall injections with lidocaine 2%
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Carpal Tunnel Syndrome
Decision Making in Hypothetical Carpal Tunnel Syndrome
Participants will be presented with a hypothetical scenario of carpal tunnel and asked to make a decision for that case.
- Trial name
- NCT03730376
- Testing
- Cost Information
- Where
- United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Stanford University
Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth Disease (CMT) Infant Scale (INC-6611)
The purpose of this study is to develop and validate a clinical outcome measure to evaluate disability and disease progression of children 3 years of age and younger (infants and toddlers) with various types of…
- Trial name
- NCT02979145
- Testing
- No intervention involved
- Where
- 4 sites in United States, Australia and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sydney Children's Hospitals Network
Carpal Tunnel, Carpal Tunnel Syndrome
Evaluation of Carpal Tunnel Syndrome in Pregnancy
Carpal tunnel syndrome (CTS) is a condition that happens when the median nerve in the wrist gets compressed, causing pain, numbness, and tingling in the hand and fingers.
- Trial name
- NCT05839769
- Testing
- Evaluation of median nerve with ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Thoracic Outlet Syndrome
The Effectiveness of Diagnosis and Treatment of Thoracic Outlet Syndrome
Thoracic Outlet Syndrome (TOS) is a condition causing numbness, tingling and weakness in patient's upper limbs. Symptoms are due to compression and restriction of the nerves and blood vessels (neurovascular bundle) that extend…
- Trial name
- NCT01342068
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Carpal Tunnel Syndrome
Median Nerve Function During Phalen's Test
This study will use electromyography and nerve conduction studies to evaluate median nerve function during the Phalen's wrist flexion test in different wrist positions.
- Trial name
- NCT05965791
- Testing
- Phalen's wrist flexion test
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Carpal Tunnel Syndrome
Role of Ultrasonography in the Diagnosis of Carpal Tunnel Syndrome
This prospective study aims to evaluate the median nerve in Carpal Tunnel Syndrome by high-frequency ultrasound and color Doppler in comparison with clinical and Nerve conduction studies.
- Trial name
- NCT04976998
- Testing
- imaging
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Carpal Tunnel Syndrome (CTS)
Diagnostic Value of Digital Infrared Thermographic Imaging in Diagnosing Carpal Tunnel Syndrome
The goal of this observational study is to evaluate skin temperature patterns measured by infrared thermography in patients with carpal tunnel syndrome (CTS).
- Trial name
- NCT07699289
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hereditary Spastic Paraplegia
Phenotypes, Biomarkers and Pathophysiology in Hereditary Spastic Paraplegias and Related Disorders
The aim of this study is to determine the clinical spectrum and natural progression of Hereditary Spastic Paraplegias (HSP) and related disorders in a prospective multicenter natural history study, identify digital, imaging and…
- Trial name
- HSP-PBP (NCT03981276)
- Testing
- Clinical rating scale to measure disease severity and progression, Next-Gen Sequencing (NGS)
- Where
- 13 sites in Austria, Germany and 1 more
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Dr. Rebecca Schule
Hand Osteoarthritis, Trigger Finger
Does Adding Lidocaine to Corticosteroid Injections Reduce Pain Intensity in Hand Surgery
The purpose of this study was to determine whether adding Lidocaine to Corticosteroid injections reduce pain intensity in hand surgery.
- Conditions
- Hand Osteoarthritis, Trigger Finger, Carpal Tunnel Syndrome
- Trial name
- NCT06188221
- Testing
- Lidocaine, Corticoids
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Chronic Kidney Disease, Renal Osteodystrophy
Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients
Sclerostin, the product of the SOST gene, located on chromosome 17, locus q11.2 in humans, was originally believed to be a non-classical Bone morphogenetic protein (BMP) antagonist.Sclerostin was recently identified as a…
- Conditions
- Chronic Kidney Disease, Renal Osteodystrophy, Left Ventricular Hypertrophy
- Trial name
- NCT01382966
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- RFM Renal Treatment Services
Alzheimer Disease, Cognitive Dysfunction, Cognitive Disorder
DIV-AD BARCELONA: Alzheimer's Blood-Based Biomakers for a Diverse Community
The DIV-AD study aims to find out whether levels of Alzheimer's disease markers in blood differ among the main ethnical groups living in central Barcelona.
- Conditions
- Alzheimer Disease, Cognitive Dysfunction, Cognitive Disorder, Dementia, Neurodegenerative Disease
- Trial name
- DIV-AD (NCT07521722)
- Where
- Spain
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Carpal Tunnel Syndrome, De Quervains Tenosynovitis
The SToICAL Study - The Soft Tissue Injection of Corticosteroid And Local Anaesthetic Study
Some hand conditions can be treated with a steroid injection. Some doctors mix the steroid with local anaesthetic in the hope that the patient will experience less pain after the injection. Some doctors do not do this.
- Conditions
- Carpal Tunnel Syndrome, De Quervains Tenosynovitis, Trigger Finger
- Trial name
- SToICAL (NCT04253457)
- Testing
- 1ml of triamcinolone (40mg/1ml)
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Carpal Tunnel Syndrome, Wound Infection
abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release
Carpal Tunnel Syndrome is a prevalent condition, up to 9% in women and 0.6% in men. Surgical decompression in the most effective treatment. After surgery, approximately 1,8% of the patients develop a wound infection.
- Conditions
- Carpal Tunnel Syndrome, Wound Infection, Suture, Complication
- Trial name
- SENSE (NCT05431101)
- Testing
- Carpal Tunnel Release
- Where
- 2 sites in Netherlands
- Volunteers
- 2,604 people, healthy volunteers welcome
- Sponsor
- Gelre Hospitals
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Vasculitic Neuropathy
Polyneuropathy, Impairments and Physical Activity - The PolyImPAct Study
The project aims to investigate the validity, and reliability of outcome measures of muscle strength, functioning (gait, balance, and fine motor skills), physical activity, and patient-reported outcome measures of functioning…
- Conditions
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Vasculitic Neuropathy, POEMS Syndrome, Multifocal Motor Neuropathy
- Trial name
- PolyImPAct (NCT06040567)
- Testing
- Validity and reliability of outcome measures in polyneuropathy, Healthy controls
- Where
- Denmark
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hereditary Spastic Paraplegia, SPG47
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biological samples (skin and/or blood and/or saliva) from male and female…
- Conditions
- Hereditary Spastic Paraplegia, SPG47, SPG50, SPG51
- Trial name
- HSP (NCT04712812)
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital