Clinical trials: Nerve Examination
Neuroendocrine Tumors, Carcinoid Tumors
68Ga-Dotatoc Positron Emission Tomography (PET) for Somatostatin Receptor-Positive Neuroendocrine Tumors (NETs)
This study plans to demonstrate the safety and efficacy of [68Ga]-DOTA-tyr3-Octreotide ([68Ga]-DOTATOC) as an accurate imaging technique for diagnosis, staging, and monitoring of response to treatment in patients with…
- Trial name
- NCT02359500
- Testing
- 68Ga-DOTATOC PET
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Lale Kostakoglu
Neurofibromatosis 1
A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1
The goal of this fully decentralized, randomized controlled trial is to compare the efficacy of two educational interventions for individuals with Neurofibromatosis 1 (NF1).
- Trial name
- NCT06262113
- Testing
- Letters about NF1 Care (Content Type 1), Letters about NF1 Care (Content Type 2)
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Massachusetts General Hospital
Ultrasonography, Peroneal Neuropathies
High-resolution Ultrasound in Lower Extremity Nerves and Common Fibular Neuropathies.
This study establishes reference material of selected lower extremity nerves at pre-defined sites with high-resolution ultrasound.
- Trial name
- NCT03560505
- Testing
- Ultrasound protocol
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sándor Beniczky
Glioblastoma Multiforme
ExAblate Blood-Brain Barrier Disruption for Glioblastoma in Patients Undergoing Standard Chemotherapy
The purpose of this study is to evaluate the safety of the ExAblate Model 4000 Type 2.0 used as a tool to disrupt the BBB in patients with Glioblastoma undergoing standard of care therapy.
- Trial name
- NCT03712293
- Testing
- BBB Disruption with Chemotherapy Arm
- Where
- South Korea
- Volunteers
- 9 people
- Sponsor
- InSightec
Head and Neck Neoplasms, Accessory Nerve Injury
Therapeutic Resistance Group Exercise Training for Head & Neck Cancer Survivors
The investigators will conduct a randomized controlled trial examining 12-week, 24-week and one year outcomes from a combined therapeutic and physical exercise program that aims to bridge head-and-neck cancer survivors from acute…
- Conditions
- Head and Neck Neoplasms, Accessory Nerve Injury, Fatigue
- Trial name
- TARGET (NCT02647021)
- Testing
- Therapeutic Exercise, Therapeutic + Lower Body Exercise
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Melanoma
Retrospective Assessment of Adverse Events-related Healthcare Resource Utilization and Costs of Immune Checkpoint Inhibitor and Targeted Therapy for Adjuvant Treatment of Melanoma
This was a retrospective cohort study using the PharMetrics database. The analysis was conducted using the most recent 5 years of data from the database, January 1, 2015, to October 30, 2020.
- Trial name
- NCT05714371
- Testing
- Nivolumab, Ipilimumab + nivolumab, Pembrolizumab
- Where
- United States
- Volunteers
- 618 people
- Sponsor
- Novartis Pharmaceuticals
Ewing Sarcoma Family of Tumors
Assessment of MGMT Promoter Methylation in Advanced Ewing Sarcoma Treated With Temozolomide and Irinotecan
This is a biological study in patients with advanced Ewing Sarcoma who received, according, clinical practice, temozolomide and irinotecan The O6-methylguanine-DNA methyltransferase (MGMT) methylation status, will be correlated…
- Trial name
- MGMTLiberati (NCT03542097)
- Testing
- MGMT methylation evaluation
- Where
- 5 sites in Italy, United Kingdom
- Volunteers
- 82 people
- Sponsor
- Istituto Ortopedico Rizzoli
Mandibular Fracture Trauma, Mandible Fracture
Fixation of Fractures at Anterior Transition Zone Using Three Different Miniplates Configurations
Fractures involving the anterior transition zone of the mandible are frequently encountered and hold particular clinical significance due to the presence of the mental nerve.
- Trial name
- NCT07058597
- Testing
- Twinfork plate, 3D-interlocking plate, Miniplate
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Alexandria University
Glioblastoma
F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery
This early phase I trial studies how well F18 fluciclovine positron emission tomography (PET)/computed tomography (CT) works in assessing tumor volume and radiation therapy response in patients with glioblastoma undergoing…
- Trial name
- NCT03926507
- Testing
- Computed Tomography, Fluciclovine F18, Positron Emission Tomography
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- M.D. Anderson Cancer Center
Knee Osteoarthristis
Femoral Nerve Mobilization for Patients With Knee Osteoarthritis
Background: Knee osteoarthritis (KO) is considered as a cause of disability among the elderly, causing pain, reduced quality of life, and decreased functionality.
- Trial name
- RCT (NCT07329205)
- Testing
- traditional physical therapy, Femoral nerve mobilization
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Nerve Compression
Neurologic Examination of Wide and Narrow Tourniquets
Nerve injury is a serious potential complication associated with the clinical use of exsanguinating tourniquets in surgery. Recently, a novel narrow tourniquet has been proposed, with the claim that it may cause less compression…
- Trial name
- HEM (NCT02023476)
- Testing
- MRI
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Peripheral Nerve Injury
Comparing Primary With Secondary Repair of Based on Electrodiagnostic Assessment and Clinical Examination
The purpose of this study is to determine which surgical approach is better for clean transection injury in peripheral nerves in outcomes.
- Trial name
- NCT01116362
- Testing
- primary repair, secondary repair
- Where
- Iran
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anesthesia, Local
Pain Assessment During Mandibular Nerve Block Injection With the Aid of Dental Vibe Tool in Pediatric Dental Patients
The purpose of this study is to valuate the effectiveness of DentalVibe(DV) tool in pain reduction during local anesthetic injection compared to traditional injection without aid of DentalVibe in pediatric patients.
- Trial name
- NCT03790540
- Testing
- DentalVibe, Topical Benzocaine 20%
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Nourhan M.Aly
Overactive Bladder Syndrome
Physiotherapy in Overactive Bladder: Electrical Stimulation Treatment
To evaluate the efficacy of combined transvaginal electrical stimulation (ES) and transcutaneous tibial nerve electrical stimulation (TTNS) in the treatment of female overactive bladder syndrome (OAB).
- Trial name
- OAB (NCT03250650)
- Testing
- TTNS, ES+TTNS
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- University of Sao Paulo General Hospital
Glioma, Glioblastoma
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption
The purpose of this study is to evaluate the safety of the ExAblate Model 4000 Type 2 used as a tool to disrupt the BBB (blood brain barrier) in patients with high grade glioma undergoing standard of care therapy.
- Trial name
- NCT03551249
- Testing
- Focused ultrasound (FUS)
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- InSightec
Glioma, Radiation Therapy Patient
Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy
This trial studies the feasibility of monitoring step count as a measure of physical activity in patients with newly diagnosed glioma undergoing radiation therapy.
- Trial name
- NCT04186832
- Testing
- FitBit, Pedometer, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Nerve Block, Surgery
Ultrasound Guided Topographic Mapping of Medial Antebrachial Cutaneous Nerve
Blocking the medial antebrachial cutaneous nerve (MACN) during an axillary block often a subcutaneous wheal of local anesthetics is made what is described as painful.
- Conditions
- Nerve Block, Surgery, Anesthesia, Brachial Plexus Block
- Trial name
- NCT03211949
- Testing
- axillary block, Scandicaine
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Pain, Neck Pain
Electrical Stimulation in Individuals With Chronic Neck Pain
The primary objective of the study was to evaluate the effects of diadynamic current and transcutaneous electrical nerve stimulation on pain and function in participants with chronic neck pain.
- Conditions
- Pain, Neck Pain, Neck Pain Chronic, Pain Intensity Assessment
- Trial name
- NCT06911125
- Testing
- TENS, Diadinamic Current, Control grup
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Afyonkarahisar Health Sciences University
Bell's Palsy, Facial Nerve Paralysis
Validation of Artificial Intelligence-Based Facial Paralysis Assessment in Patients With Bell's Palsy
This observational study aims to assess the concurrent validity of an artificial intelligence (AI)-based facial paralysis assessment system in patients with unilateral Bell's palsy.
- Trial name
- AI-FACE (NCT07573358)
- Testing
- Sunnybrook Facial Grading System (FGS), AI-Based Facial Assessment
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Cairo University
Depression
Investigation to Understand and Optimize Psilocybin
This study will examine the effects of a single dose of psilocybin, administered with psychological support, on symptoms of depression.
- Trial name
- OPTIMIZE (NCT06512194)
- Testing
- Psilocybin, Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Charles Raison