Clinical trials: Nerve Pain
Gastrointestinal Diseases, Autonomic Nervous System Disease
Relationship of Cervical Region Tension With Vagal Function
The increase in the tension of the soft tissues around a nerve restricts the movement, affects the function of the nerve, and makes the nerve vulnerable to entrapment.
- Trial name
- NCT05325879
- Testing
- VAGUS-NDT
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Anterior Cutaneous Nerve Entrapment Syndrome
Effect of Abdominal Wall Injections on Abdominal Pain
This is a prospective cohort study of outpatient adults with chronic abdominal wall pain receiving abdominal wall injections, as part of their usual care, with lidocaine.
- Trial name
- NCT06121466
- Testing
- Abdominal wall injections with lidocaine 2%
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Painful Diabetic Neuropathy
Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve Compression
The UT Southwestern Medical Center at Dallas would like to give you information about a research study that is being done for patients with painful diabetic neuropathy and have not responded to medical treatment.
- Trial name
- DNND (NCT00703209)
- Testing
- Nerve Decompression
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Patient Satisfaction
Effect of VR on Pain and Patient Satisfaction in Adults Receiving GNRFA
The study team aims to investigate whether implementing virtual reality therapy (VRT) during Genicular nerve radiofrequency ablation (GNRFA) procedure will provide better alleviation of procedural pain and augmented satisfaction…
- Trial name
- NCT05468398
- Testing
- Soothe VR
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Labor Pain
Transcutaneous Electrical Nerve Stimulation for Labor Pain Control
Transcutaneous electrical nerve stimulation (TENS) is a non-invasive electro-physical modality used for several pain conditions including labor pain control.
- Trial name
- NCT04894539
- Testing
- DS5 electrical stimulator
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Postoperative Pain, Cesarean Section
Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression
At the end of your cesarean section surgery, which is started by applying medication to the spinal cavity from your waist, pain medication will be applied between the relevant muscle and its covering from your lower abdomen or…
- Conditions
- Postoperative Pain, Cesarean Section, Postpartum Depression
- Trial name
- NCT06221280
- Testing
- Nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Rotator Cuff Tears, Shoulder Pain
Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair
This study is a comparison of analgesia effect from peripheral nerve blockade (PNB) with liposomal bupivacaine combined with bupivacaine compared to PNB with ropivacaine combined with dexamethasone for arthroscopic rotator cuff…
- Trial name
- NCT04737980
- Testing
- Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Ropivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery Florida
Knee Osteoarthritis
Comparative Study Between Intra Articular Injection of Hyaluronic Acid (HA) With Platelet Rich Plasma (PRP) Versus Genicular Nerve Thermal Radiation in Management of Pain in Knee Osteoarthritis
Intraarticular injection (IAI) of Platelet rich plasma (PRP) with Hyaluronic acid (HA) Versus Radiofrequency (RF) of genicular nerve for pain reduction of of knee osteoarthritis , Improving daily activity and reduction analgesia…
- Trial name
- NCT04188561
- Testing
- Intra articular injection Group, Radiofrequency Group
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Pain
Bupivacaine Digital Blocks: How Long is the Pain Relief and Temperature Elevation?
No one knows how long bupivacaine finger blocks last. Many use bupivacaine with and without epinephrine, but no one knows how the epinephrine affects the duration of the block.
- Trial name
- NCT01698593
- Testing
- Bupivacaine 0.5%, Bupivacaine 0.5% + Epinephrine (1:200,000)
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Lalonde, Donald H., M.D.
Carpal Tunnel Syndrome
Effects of Kinesiotaping With and Without Active Release Technique in Patients With Carpal Tunnel Syndrome
The goal of this study is to compare the effects of Kinesiotaping and Active Release Technique in patients with CTS to see which method is better for improving Pain, Grip Strength, Range of Motion and functional disability.
- Trial name
- NCT05354011
- Testing
- Kinesiotape, Active Release Technique
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hand Osteoarthritis, Trigger Finger
Does Adding Lidocaine to Corticosteroid Injections Reduce Pain Intensity in Hand Surgery
The purpose of this study was to determine whether adding Lidocaine to Corticosteroid injections reduce pain intensity in hand surgery.
- Conditions
- Hand Osteoarthritis, Trigger Finger, Carpal Tunnel Syndrome
- Trial name
- NCT06188221
- Testing
- Lidocaine, Corticoids
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Ilioinguinal Nerve Section, Pain Prevention
Prophylactic Ilioinguinal Neurectomy During Open Tension-Free Inguinal Hernia Repair
postoperative chronic inguinal pain is a common postoperative complication after open inguinal hernia repair. Chronic inguinal pain is a common complication following open inguinal hernia repair.
- Conditions
- Ilioinguinal Nerve Section, Pain Prevention, Hernioplasty
- Trial name
- NCT06327763
- Testing
- ilioinguinal nerve section
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Vertebral Compression Fracture, Facet Joint Pain
Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures
The purpose of this study is to test the efficacy of radiofrequency ablation of the medial branch nerves (RFA-MBN) in relieving pain and improving physical function in patients with subacute and chronic vertebral compression…
- Trial name
- NCT03651804
- Testing
- Radiofrequency ablation of the medial branch nerves, Non-steroidal anti-inflammatory drugs, Bisphosphonates
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Pain
Preanalgesic Effect of Gabapentin in Total Knee Repair
The purpose of this study is to determine whether gabapentin, as a one time administration prior to a total knee replacement procedure, has opioid sparing effects and a reduction in pain scores.
- Trial name
- NCT00279487
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas Health Resources
Pain
The Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Lower Jaw Dental Injections
The inferior alveolar nerve block (shot) is the most frequently used injection technique for achieving local anesthesia (numbness) for the teeth in the lower jaw.
- Trial name
- NCT01574807
- Testing
- mepivacaine + lidocaine followed by lidocaine +lidocaine, lidocaine + lidocaine followed by mepivacaine + lidocaine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Neuropathic Pain
A Study to Investigate the Pharmacodynamic Effects of CT327 on Intra-dermal Nerve Growth Factor (NGF) and Evoked Pain Responses, in Healthy Male Volunteers
The primary objective of this study is to compare the effect of CT327 to placebo against experimental induced superficial, deep and hyperalgesic pain.
- Trial name
- NCT01243307
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Creabilis SA
Healthy, Nerve Block
HFAC Stimulation (30-50 Kilohertz) in Healthy Volunteers (High Frequency Alternating Current Stimulation)
High-frequency alternating current (HFAC) stimulation (between 1 kilohertz (kHz) and 100 kHz) on the peripheral nerve has been shown in basic animal research to produce a rapidly reversible nerve block without nerve damage.
- Conditions
- Healthy, Nerve Block, Pain
- Trial name
- HFA (NCT05230836)
- Testing
- High-frequency alternating current stimulation
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Post-operative Pain
Comparison of Preoperative Ultrasound Guided Pectoralis Nerve Block Placement Versus Intra-operative Placement: A Prospective Randomized Trial
This study investigates the use of post-operative on-Q pain catheters for tissue expander based breast reconstruction, versus conventional ultrasound-guided blocks placed pre-operatively.
- Trial name
- NCT03201809
- Testing
- On-Q, Ultrasound guided pectoral nerve block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital