Clinical trials: Nerve Pain
Cesarean Section, Post Operative Pain
Ilioinguinal Iliohypogastric Nerve Block as Adjunct to Spinal Anesthesia for Cesarean Section
The aim of the present controlled randomized study is to compare between ilioinguinal/iliohypogastric nerve block (IINB) and morphine as adjuncts to spinal anesthesia for cesarean section regarding quality of post-operative…
- Trial name
- NCT06108895
- Testing
- ilio-inguinal/ilio-hypogastric nerve block (IINB), intrathecal morphine
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Low Back Pain, Nerve Entrapment Syndrome
Ultrasound Localization and Guided Injection for Superior Cluneal Nerve Entrapment
Low back pain (LBP) is a common complaint in the clinical setting. Among all the differential diagnosis for LBP, superior cluneal nerve (SCN) entrapment is the commonly omitted one.
- Trial name
- NCT04478344
- Testing
- Ultrasound guided hydrodissection of superior cluneal nerve
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Fibromyalgia
Vagus Nerve Stimulation for Treating Adults With Severe Fibromyalgia
Fibromyalgia syndrome (FMS) is a long-term disorder that is characterized by widespread body pain and tender points in joints, muscles, tendons, and other soft tissues.
- Trial name
- NCT00294281
- Testing
- Vagus Nerve Stimulation (VNS) Therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Knee Pain
Genicular Nerve Block for Knee Pain in the ED
Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.
- Trial name
- NCT07158736
- Testing
- Genicular nerve block with bupivacaine and corticosteroids, Standard of Care
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
Experimental Pain in Healthy Human Subjects
Tonic Pain and Transauricular Vagal Nerve Stimulation
This study aims to explore the effect of burst-taVNS (electric stimulation of the concha cymba) on tonic (capsaicin-induced skin pain) and acute (pressure pain sensitivity) experimental pain and cardioception.
- Trial name
- NCT07325058
- Testing
- taVNS, Earlobe Stimulation
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Carpal Tunnel Syndrome, Pain, Chronic
Median Nerve Hydro-dissection Using Single Injection of Hyalase as a Novel Treatment of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline of the median nerve could offer symptoms and clinical improvement
- Trial name
- NCT03177915
- Testing
- Hylase, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Knee Osteoarthritis, Persistent Postsurgical Pain
Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain
Chronic knee pain remains a disabling disease despite current treatment strategies. There is an increase in the prevalence of osteoarthritis (OA) of the knee in the general population, presently affecting approximately 450,000…
- Conditions
- Knee Osteoarthritis, Persistent Postsurgical Pain, Chronic Knee Pain
- Trial name
- COGENIUS (NCT05407610)
- Testing
- Conventional Radiofrequency ablation of the genicular nerves, Cooled Radiofrequency ablation of the genicular nerves
- Where
- 15 sites in Belgium, Netherlands
- Volunteers
- 400 people
- Sponsor
- Ziekenhuis Oost-Limburg
Post Operative Pain
Ketamine and Dexmedetomidine Comparative Study
In this study, the investigators will compare the effect of adding ketamine and dexmedetomidine to bupivacaine in US-guided combined sciatic and femoral nerve blocks as regards the onset and duration of the block, postoperative…
- Trial name
- NCT06032624
- Testing
- combined ultra-sound guided femoral and sciatic nerve block.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Postoperative Pain
Ultrasound Guided Distal Peripheral Nerve Blocks and Postoperative Pain.
The aim of this clinical trial is to determinate if distal ultrasound guided peripheral nerve blocks on target nerves (radial and median nerve blocks at the elbow), using low volume and low concentration of long acting local…
- Trial name
- NCT01597479
- Testing
- Levobupivacaine
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Postoperative Pain
Dexmedetomidine vs. Tramadol With Ropivacaine in Ultrasound-Guided PENG Block for Hip Surgery
To compare the mean onset of sensory block and mean time to first rescue analgesia between ropivacaine with dexmedetomidine and ropivacaine with tramadol in ultrasound-guided pericapsular nerve group block for postoperative…
- Trial name
- NCT07863544
- Testing
- Pericapsular nerve group block
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Verteborgenic Low Back Pain, Back Pain Lower Back
A Prospective Cohort Study of Basivertebral Nerve Ablation Using the Stryker OptaBlate BVN System for the Treatment of Vertebrogenic Low Back Pain
The goal of this observational study is to evaluate patient outcomes following treatment of vertebrogenic low back pain using the Stryker OptaBlate BVN System.
- Trial name
- OptaBlate BVN (NCT07392333)
- Testing
- Basivertebral nerve ablation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stryker Instruments
Popliteal Nerve Block, Foot Surgery
Continuous Popliteal Nerve Blocks: Effect of Perineural Catheter Tip Location Relative to the Sciatic Nerve Bifurcation on Postoperative Analgesia
Research study to determine the relationship between perineural catheter tip location relative to the sciatic nerve bifurcation and postoperative analgesia for continuous popliteal nerve blocks.
- Conditions
- Popliteal Nerve Block, Foot Surgery, Ankle Surgery, Popliteal Bifurcation
- Trial name
- NCT01229696
- Testing
- Catheter Placed At Bifurcation, Catheter Placed 5cm Above Bifurcation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Diego
Arthritis Knee
Trial to Compare Femoral Nerve Block With Local Anaesthetic Injection for Post-operative Pain After Knee Replacement.
Pain after a knee replacement can impair recovery and use of the new knee. Having an injection to numb the femoral nerve is known to give good pain relief after the operation but may lead to slower mobilisation as it also…
- Trial name
- LIFT (NCT02288923)
- Testing
- Femoral nerve block, Local Infiltration Analgesia, Sub arachnoid analgesia
- Where
- United Kingdom
- Volunteers
- 199 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Nerve Compression Syndromes, Neuropathic Pain
The Effectiveness of Tibial Nerve Mobilization in Patients With Tarsal Tunnel Syndrome
This randomized, clinical, single-blinded, controlledstudywasinitiallyplannedtoinclude 35 patients diagnosed with tarsal tunnel who applied to Kütahya Health Sciences University, Evliya Çelebi Training and Research Hospital…
- Trial name
- NCT05307354
- Testing
- Tibial Nerve Mobilization, Foot-ankle range of motion exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Trigeminal Neuralgia
Phenytoin as Treatment for Acute Exacerbations of Trigeminal Neuralgia - a Prospective Systematic Study of 20 Patients
The nature of trigeminal neuralgia (TN) is fluctuating and patients can experience periods of complete remission of pain as well as periods with excessive pain.
- Trial name
- NCT03712254
- Testing
- Fosphenytoin
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Danish Headache Center
Postoperative Pain Management
The Efficacy of Combined Intrathecal Morphine and PENG Block on Postoperative Pain in Hip Arthroplasty
This study aims to compare the postoperative 48-hour period in terms of morphine consumption, postoperative pain, and quality of recovery scores by combining the Pericapsular Nerve Group (PENG) block with low-dose intrathecal…
- Trial name
- PENG (NCT06298370)
- Testing
- Pericapsular nerve group block plus intrathecal bupivacaine, Intrathecal bupivacaine and morphine, Pericapsular nerve group block plus intrathecal bupivacaine and morphine
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Bezmialem Vakif University
Mitral Regurgitation, Pain, Postoperative
Cryoablation of Intercostal Nerves for Pain Management in Early Postoperative Period in Patients With Minimally Invasive Mitral Valve Surgery
A single-center, pilot, prospective, randomized clinical trial with a 1:1 allocation ratio. The aim of our trial is to determine whether cryoablation of intercostal nerves provides a clinically significant analgesic effect, which…
- Trial name
- BLOCK (NCT06443931)
- Testing
- cryoablation of intercostal nerves
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Hip Fractures, Pain, Acute
Ultrasound Guided Nerve Block for Hip Fracture Pain Management at Emergency Department
The main objective is to determine if ultrasound guided suprainguinal iliac fascia block leads in better clinical outcomes such as pain management or time to home discharge.
- Conditions
- Hip Fractures, Pain, Acute, Ultrasound Therapy; Complications
- Trial name
- NCT05403073
- Testing
- Ultrasound guided Suprainguinal Iliac Fascia Nerve Block.
- Volunteers
- 72 people
- Sponsor
- Hospital San Carlos, Madrid
Opioid Use, Pain Postoperative
Comparison of Pain Relief After Arthroscopic Knee Surgery: Adductor Canal Block and Genicular Nerve Block
This prospective randomized study aims to compare the analgesic efficacy of Adductor Canal Block (ACB) and Genicular Nerve Block (GNB) groups to relieve postoperative pain in participants between ages of 18-72 undergoing…
- Conditions
- Opioid Use, Pain Postoperative, Arthroscopic Knee Surgeries
- Trial name
- NCT06909851
- Testing
- Adductor Canal Block (ACB), Genicular Nerve Block (GNB)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Pain, Anesthesia
Analgesic Effects of Rhomboid Block
Breast surgery is a common surgical procedure because of the prevalence of breast cancer. Postoperative analgesia management in breast surgery is difficult due to the content of the surgical procedure and the complex innervation…
- Trial name
- NCT03942003
- Testing
- rhomboid blocks, PEC blocks, Control groups
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital