Clinical trials: Nervous System
Cerebral Palsy
Balance and Posture in Adults With Cerebral Palsy
The results of this study will have an impact upon public heath policy as adults with cerebral palsy (CP) present a growing and underserved population in the United States.
- Trial name
- NCT01585571
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Temple University
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Idiopathic Intracranial Hypertension
Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension
The proposed study aims to evaluate optic nerve head blood flow and microcirculation in patients with idiopathic intracranial hypertension.
- Trial name
- NCT06545981
- Testing
- Lumbar puncture and administration of medication
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Emergence Agitation, Nasal Surgery
Emergence Agitation
The impact of sugammadex on agitation upon emergence following adult nasal surgeries is an issue which needs to be studied that links anesthetic management with postoperative recovery.
- Trial name
- Sugamadex (NCT07253428)
- Testing
- Neostigmine + Atropine, Sugamadex
- Where
- Saudi Arabia
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Usher Syndrome Type 3
BF844 Safety and Pharmacokinetic Study in Healthy Volunteers
First-in-Human Phase-1 Clinical Trial to Assess Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Ascending Doses of BF844 when Administered Orally to Healthy Adult Participants.
- Trial name
- NCT06592131
- Testing
- BF844
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- EyeXCel Pty. Ltd.
Multiple Sclerosis, Sexual Dysfunction
Multiple Sclerosis Intimacy and Sexuality Questionnaire
Aims: This study aimed to psychometrically evaluate the Turkish version of the Multiple Sclerosis Intimacy and Sexuality Questionnaire (MSISQ-15) in women with MS. Methods: The study included 130 women with MS.
- Conditions
- Multiple Sclerosis, Sexual Dysfunction, Questionnaires
- Trial name
- NCT05374031
- Testing
- descriptive study
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Bozok University
Migraine, Headache
The Role of CGRPand Nociceptin in Migraine
The release of the neuropeptide calcitonin gene-related peptide (CGRP) is thought to play a causative role in migraine. Nociceptin immunoreactivity and ORL-1 mRNA have been detected in human trigeminal ganglia where it was…
- Trial name
- NCT00155129
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Quality of Life, Insomnia
The Efficacy of Group-based Unified Protocol (UP) Programme for Improving Sleep and Mental Health
Common mental disorders can be disabling and lead to a large burden of disease. Unified Protocol for Transdiagnostic Treatment of Emotional Disorders was developed to address emotional disorders with evidence-based…
- Conditions
- Quality of Life, Insomnia, Depression, Anxiety
- Trial name
- NCT05394753
- Testing
- Unified Protocol for mood disorders
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Fascia, Trigger Point Pain, Myofascial
Effects of Myofascial Induction Therapy on Pressure Pain and Ankle Range of Motion.
In this study, it will be assessed if there are changes in ankle dorsiflexion and pressure pain after performing the myofascial induction technique in the calf.
- Conditions
- Fascia, Trigger Point Pain, Myofascial, Range of Motion, Pain
- Trial name
- NCT05711745
- Testing
- Calf myofascial technique
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Post Operative Pain
Comparison Between Two Blocks in Analgesia After Knee Arthroplasty
Comparative Study between Adductor canal block combined with infiltration OF The interspace between popliteal artery and the capsule of the knee block versus genicular nerves Block combined with IPACK in Postoperative analgesia…
- Trial name
- NCT07046377
- Testing
- ACB - IPACK, GNB - IPACK
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain
The Effect of Warming and Vibration Applications on Pain in Newborns
This study aimed to determine the effects of warming and vibration applications on pain during heel blood collection in newborns. H1: Warming application has a positive effect on pain during heel blood collection in newborns.
- Trial name
- NCT06607575
- Testing
- Control group, Warming, Vibration
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Depression, Involutional
Function of Catecholamines in the Brain During Depression
This study will explore brain function related to depressive symptoms and will examine DNA for genes that may be involved in depressive disorders, particularly genes that regulate synthesis and metabolism of the brain…
- Trial name
- NCT00082030
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Hernia, Pain, Postoperative
Pilot Study: Rectus Sheath Blocks for Improving Abdominal Surgery Conditions
The purpose of this study is to show that the use of preoperative rectus sheath blocks can ultimately alleviate the need for using nondepolarizing muscle relaxants during certain abdominal procedures.
- Conditions
- Hernia, Pain, Postoperative, Abdominal Wall Relaxation After Rectus Sheath Block
- Trial name
- NCT02447965
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Vestibular Function Tests
Computerized Rotational Head Impulse Test-Vertical (crHIT-vertical)
The purpose of this research study is to test whether a Computerized Rotational Head Impulse Test-Vertical (crHIT-vertical) is able to reliably evaluate the vertical semicircular canals in patients with vestibular dysfunctions.
- Trial name
- NCT04087044
- Testing
- Computerized Rotational Head Impulse Test ( crHIT)-Vertical
- Where
- 3 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Neurolign
Intervertebral Disc Degeneration, Back Pain
Tissue Collection for Understanding Intervertebral Disc Degeneration and Back Pain
The purpose of the research is to collect and examine spinal disc and ligament tissues to see if there are any biological markers that can be correlated with MRI images to help us learn more about causes of back pain.
- Trial name
- NCT01633034
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Stroke, Seizures
Epilepsy Watch After Vascular Events: Frequency, Outcomes, and Risk Markers
This research aims to determine the frequency of seizures in patients following a stroke, identify risk factors associated with post-stroke seizures, and characterize EEG changes linked to these seizures.
- Conditions
- Stroke, Seizures, EEG Power Spectra, Serum Biomarkers
- Trial name
- EY-WAVEFORMS (NCT06922734)
- Where
- Slovenia
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Alzheimer's Disease, Dementia
A Study of Acupuncture for Patients With Behavioural and Psychological Symptoms of Dementia
The purpose of the study is to evaluate the safety and tolerability of acupuncture for patients with BPSD \& healthy volunteers.
- Trial name
- NCT01055561
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Aphasia, Language Disorders
Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis
The purpose of this investigation is to further develop and test a treatment for word-finding problems in aphasia. The treatment is designed to strengthen meaning associations within categories of words (e.g., animals, tools…
- Conditions
- Aphasia, Language Disorders, Speech Disorders
- Trial name
- NCT00125242
- Testing
- Semantic Feature Analysis (SFA)Training
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Aphasia
Effect of Communication Partner Training Program for the Management of Persons With Aphasia
Communication Partner Training (CPT) is an evidence-based intervention that teaches communication partners (e.g., family members, friends, healthcare workers) how to best support conversation and interaction for a person with…
- Trial name
- NCT05225922
- Testing
- Communication Partner Training, Usual Speech and language Therapy
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pain
Topical Local Anaesthesia and Cooling During Capsaicin 8% Patch Application
Aim of the study is to demonstrate superiority of a continuous cooling of the skin over topical EMLA or placebo in reducing the burning pain during the application of capsaicin 8% patch ("Qutenza").
- Trial name
- LACCA (NCT01523951)
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
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